Ruling in and ruling out: Implications of molecular genetic diagnoses for disease classification

Social Science and Medicine

Volumn 61, Issue 12, 2005, Pages 2536-2545

  Miller, Fiona Alice ^a,b,c   Ahern, Catherine ^a   Ogilvie, Jacqueline ^a   Giacomini, Mita ^a,b   Schwartz, Lisa ^b  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c HAMILTON HEALTH SCIENCES   (Canada)

Author keywords

Canada; Diagnosis; Disease classification (nosology); Genetic counsellors; Genetics

Indexed keywords

HEALTH AND DISEASE;

ARTICLE; DIAGNOSTIC PROCEDURE; DISEASE CLASSIFICATION; GENE EXPRESSION; GENETIC COUNSELING; HUMAN; INTERVIEW; MOLECULAR GENETICS; QUALITATIVE ANALYSIS; SOCIAL ASPECT;

CLINICAL COMPETENCE; COMMUNICATION; DISEASE; GENETIC COUNSELING; GENETIC DISEASES, INBORN; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; HUMANS; INTERVIEWS; MOLECULAR BIOLOGY; ONTARIO; PROFESSIONAL-PATIENT RELATIONS; UNCERTAINTY;

EID: 27644577952     PISSN: 02779536     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.socscimed.2005.04.043     Document Type: Article

References (30)

1. R.A. Aronowitz Making sense of illness: Science, society and disease 1998 Cambridge University Press Cambridge
2. R.L. Bennett, H.L. Hampel, J.B. Mandell, and J.H. Marks Genetic counselors: Translating genomic science into clinical practice Journal of Clinical Investigation 112 9 2003 1274 1279
3. A. Bharadwaj Uncertain risk: genetic screening for susceptibility to haemochromatosis Health, Risk and Society 4 3 2002 227 240
4. B.B. Biesecker, and K. Peters Process studies in genetic counseling: Peering into the black box American Journal of Medical Genetics 106 2001 191 198
5. G.C. Bowker, and S.L. Star Sorting things out: Classification and its consequences 1999 The MIT Press Cambridge, MA and London, England
6. L.J. Ciarleglio, R.L. Bennett, J. Williamson, J.B. Mandell, and J.H. Marks Genetic counseling throughout the life cycle Journal of Clinical Investigation 112 9 2003 1280 1286
7. F.S. Collins, E.D. Green, A.E. Guttmacher, and M.S. Guyer A vision for the future of genomics research Nature 422 6934 2003 835 847
8. C. Feudtner A disease in motion: Diabetes history and the new paradigm of transmuted disease Perspectives in Biology and Medicine 39 2 1996 158 170
9. L. Fleck Genesis and development of a scientific fact 1979 The University of Chicago Press Chicago
10. L. Gannett What's in a cause? The pragmatic dimensions of genetic explanations Biology and Philosophy 14 1999 349 374
11. Haigh, B.H., Huq, M., & Hayden, M.R. (2004). Huntington Disease: GeneReviews.
12. N. Hallowell Doing the right thing: genetic risk and responsibility Sociology of Health and Illness 21 5 1999 597 621
13. A.M. Hedgecoe Expansion and uncertainty: Cystic fibrosis, classification and genetics Sociology of Health and Illness 25 1 2003 50 70
14. A.M. Hedgecoe A reply to Anne Kerr Sociology of Health and Illness 26 1 2004 107 109
15. G. Hesslow What is a genetic disease? On the relative importance of causes L. Nordenfelt &B.I.B. Lindahl Health, Disease, and Causal Explanations in Medicine 1984 Reidel Dordrecht 183 193
16. A. Kerr (Re)constructing genetic disease: The clinical continuum between Cystic Fibrosis and male infertility Social Studies of Science 30 6 2000 847 894
17. A. Kerr Giving up on geneticization: a comment on Hedgecoe's 'Expansion and uncertainty: cystic fibrosis, classification and genetics' Sociology of Health and Illness 26 1 2004 102 106
18. A. Kerr, and S. Cunningham-Burley On ambivalence and risk: Reflexive modernity and the new human genetics Sociology 34 2 2000 283 304
19. Kitcher, P. (1997). Fascinating Genetalk, The Lives to Come (pp. 329-269): Touchstone Books.
20. V.A. McKusick On lumpers and splitters, or the nosology of genetic disease Perspectives in Biology and Medicine 1969 298 312
21. Moskowitz, S.M., Gibson, R.L., Sternen, D.L., Cheng, E., & Cutting, G.R. (2004). CFTR-Related Disorders: GeneReviews.
22. Northrup, H., & Au, K.-S. (2004). Tuberous Sclerosis Complex: GeneReviews.
23. C. Novas, and N. Rose Genetic risk and the birth of the somatic individual Economy and Society 29 4 2000 485 513
24. A. Robertson Embodying risk, embodying political rationality: Women's accounts of risks for breast cancer Health, Risk and Society 2 2 2000 219 235
25. B.J. Rosenstein Cystic fibrosis diagnosis: New dilemmas for an old disorder Pediatric Pulmonology 33 2002 83 84
26. L. Sachs, A. Taube, and C. Tishelman Risk in numbers - Difficulties in the transformation of genetic knowledge from research to people Acta Oncologica 40 4 2001 445 453
27. C.R. Scriver, and P.J. Waters Monogenic traits are not simple: lessons from phenylketonuria Trends in Genetics 15 7 1999 267 272
28. M. Severinsen Principles behind definitions of disease - a criticism of the principle of disease mechanism and the development of a pragmatic alternative Theoretical Medicine and Bioethics 22 2001 319 336
29. K. Wailoo Drawing Blood: Technology and Disease Identity in Twentieth Century America 1997 Johns Hopkins University Press Baltimore, MD
30. C. Wang, R. Gonzalez, and S.D. Merajver Assessment of genetic testing and related counseling services: current research and future directions Social Science and Medicine 58 2004 1427 1442