Kadlongilactones A and B, two novel triterpene dilactones from Kadsura longipedunculata possessing a unique skeleton

Organic Letters

Volumn 7, Issue 22, 2005, Pages 5079-5082

  Pu, Jian Xin ^a,c   Xiao, Wei Lie ^a   Lu, Yang ^b   Li, Rong Tao ^a,d   Li, Hong Mei ^d   Zhang, Li ^b   Huang, Sheng Xiong ^a   Li, Xian ^a   Zhao, Qin Shi ^a   Zheng, Qi Tai ^b   Sun, Han Dong ^a  

^a KUNMING INSTITUTE OF BOTANY   (China)

^b INSTITUTE OF MATERIA MEDICA   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^d KUNMING UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

KADLONGILACTONE A; KADLONGILACTONE B; LACTONE; TRITERPENE;

ARTICLE; CELL STRAIN K 562; CHEMICAL STRUCTURE; CHEMISTRY; DRUG SCREENING; HUMAN; IC 50; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SCHISANDRACEAE; TUMOR CELL LINE; X RAY CRYSTALLOGRAPHY;

CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INHIBITORY CONCENTRATION 50; K562 CELLS; LACTONES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; SCHISANDRACEAE; TRITERPENES;

EID: 27644549035     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol052161j     Document Type: Article

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15. -1. NMR data can be found in Table 1.
16. 3. The crystal structure (1) was solved by the direct method SHELX-86 (Sheldrich, G. M. University of Gottingen: Gottingen, Germany, 1985) and expanded using difference Fourier techniques, refined by the program and method NOMCSDP (Lu, Y.; Wu, B. M. Chin. Chem. Lett. 1992, 3, 637-640) and the full-matrix least-squares calculations. Crystallographic data for the structure of 1 has been deposited in the Cambridge Crystallographic Data Centre (deposition number: CCDC 278406). Copies of these data can be obtained free of charge via www.ccdc.cam.ac.uk/conts/retrieving.html (or from the Cambridge Crystallographic Data Centre, 12, Union Road, Cambridge CB21EZ, UK; fax: (+44) 1223-336-033; or deposit@ccdc.cam.ac.uk)
17. -1. NMR data can be found in Table 1.
18. Niu, X. M.; Li, M. L.; Zhao, Q. S.; Mei, S. X.; Na, Z.; Wang, S. J.; Lin, Z. W.; Sun, H. D. Planta Med. 2002, 68, 528-33.