Lancifodilactone F: A novel nortriterpenoid possessing a unique skeleton from Schisandra lancifolia and its anti-HIV activity

Organic Letters

Volumn 7, Issue 7, 2005, Pages 1263-1266

  Xiao, Wei Lie ^a,d   Li, Rong Tao ^a   Li, Sheng Hong ^a   Li, Xiao Li ^a,d   Sun, Han Dong ^a   Zheng, Yong Tang ^b   Wang, Rui Rui ^b,d   Lu, Yang ^c   Wang, Cheng ^c   Zheng, Qi Tai ^c  

^a KUNMING INSTITUTE OF BOTANY   (China)

^b KUNMING INSTITUTE OF ZOOLOGY   (China)

^c INSTITUTE OF MATERIA MEDICA   (China)

^d UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

LANCIFODILACTONE F; TRITERPENOID; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANTI-HIV AGENTS; CRYSTALLOGRAPHY, X-RAY; DRUG SCREENING ASSAYS, ANTITUMOR; DRUGS, CHINESE HERBAL; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PLANT LEAVES; PLANT STEMS; PLANTS, MEDICINAL; SCHISANDRA; TRITERPENES;

EID: 20244381825     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0473187     Document Type: Article

References (17)

1. Chen, Y. G. Ph.D. Thesis, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China, 1998, pp 76-81.
2. Hanche, J. L.; Burgos, R. A.; Ahamada, F. Fitoterapia 1999, 70, 451-471.
3. Kuo, Y. H.; Kuo, L. Y.; Chen, C. F. J. Org. Chem. 1997, 62, 3242-3245.
4. Chen, D. F.; Zhang, S. X.; Wang, H. K.; Zhang, S. Y.; Sun, Q. Z.; Cosentino, M.; Lee, K. H. J. Nat. Prod. 1999, 62, 94-97.
5. Sun, H. D.; Qiu, S. X.; Lin, L. Z.; Wang, Z. Y.; Lin, Z. W.; Pengsuparp, T.; Pezzuto, J. M.; Fong, H. J. Nat. Prod. 1996, 59, 525-527.
6. Li, L. N.; Xue, H. Planta Med. 1986, 52, 492-493.
7. Li, L. N.; Xue, H.; Kangouri, K.; Ikeda, A.; Omura, S. Planta Med. 1989, 55, 294-296.
8. Kangouri, K.; Miyoshi, T.; Kawashima, A.; Ikeda, A.; Mizutani, T.; Omura, S.; Li, L. N.; Xue, H. Planta Med. 1989, 55, 297-299.
9. Li, L. N.; Xue, H.; Ge, D. L.; Kangouri, K.; Miyoshi, T.; Omura, S. Planta Med. 1989, 55, 300-302.
10. Li, R. T.; Zhao, Q. S.; Li, S. H.; Han, Q. B.; Sun, H. D.; Lu, Y.; Zhang, L. L.; Zheng, Q. T. Org. Lett. 2003, 5, 1023-1026.
11. Li, R. T.; Li, S. H.; Zhao, Q. S.; Lin, Z. W.; Sun, H. D.; Lu, Y. Wang, C.; Zheng, Q. T. Tetrahedron Lett. 2003, 44, 3531-3534.
12. Li, R. T.; Xiang, W.; Li, S. H.; Lin, Z. W.; Sun, H. D. J. Nat. Prod. 2004, 67, 94-97.
13. Li, R. T.; Shen, Y. H.; Xiang, W.; Sun, H. D. Eur. J. Org. Chem. 2004, 807-811.
14. 6 435.2746.
15. 2). The crystal structure (1) was solved by direct methods using SHELX-86 (Sheldrich, G. M.; University of Gottingen: Gottingen, Germany, 1985) and expanded using difference Fourier techniques, refined by the program and method NOMCSDP (Lu, Y.; Wu, B. M. Chin. Chem. Lett. 1992, 3, 637-640) and full-matrix least-squares calculations. Crystallographic data for the structure of 1 have been deposited at the Cambridge Cristallographic Data Centre (deposition number: CCDC 254747). Copies of these data can be obtained free of charge via the Internet at www.ccdc.cam.ac.uk/ conts/retrieving.html (or from the Cambridge Crystallographic Data Centre, 12, Union Road, Cambridge CB21EZ, UK; fax: (+44) 1223-336-033; or deposit@ccdc.cam.ac.uk).
16. Zheng, Y. T.; Ben, K. L.; Zhang, W. F.; Wang, J. H. Immunopharmacol. Immunotoxicol. 1995, 17, 69-79.
17. Zheng, Y. T.; Ben, K. L.; Jin, S. W. Acta Pharmacol. Sin. 1999, 20, 239-243.