Histone acetylase inhibitor trichostatin A induces acetylcholinesterase expression and protects against organophosphate exposure

Journal of Cellular Biochemistry

Volumn 96, Issue 4, 2005, Pages 839-849

  Curtin, Bryan F ^a   Tetz, Lauren M ^a   Compton, Jaimee R ^a   Doctor, Bhupendra P ^a   Gordon, Richard K ^a   Nambiar, Madhusoodana P ^a,b  

^a WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Acetylcholinesterase; Gene expression; Neuronal cell lines; Neuroprotection; Organophosphates; Transcriptional inducers

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; CHEMICAL WARFARE AGENT; DYFLOS; ENZYME INHIBITOR; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE INHIBITOR; HISTONE DEACETYLASE; NEUROTRANSMITTER; ORGANOPHOSPHATE; SARIN; SCAVENGER; SOMAN; TRANSCRIPTION FACTOR; TRICHOSTATIN A; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHEMICAL WARFARE; CHROMATIN; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME PURIFICATION; EPILEPTIC STATE; HEART FAILURE; HYDROLYSIS; LD 50; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RESPIRATORY FAILURE; RNA SYNTHESIS;

ACETYLCHOLINESTERASE; ANIMALS; CELL LINE, TUMOR; CHROMATOGRAPHY, AFFINITY; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HISTONE ACETYLTRANSFERASES; HYDROXAMIC ACIDS; ISOFLUROPHATE; MICE; NEUROPROTECTIVE AGENTS; PHOSPHORIC ACID ESTERS; PROCAINAMIDE; RNA, MESSENGER; TIME FACTORS; TRANSCRIPTION, GENETIC; UP-REGULATION;

ANIMALIA; BOVINAE; PRIMATES; RODENTIA;

EID: 27644498534     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.20591     Document Type: Article

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