A thiolate ligand on a cytochrome P-450 mimic permits the use of simple environmentally benign oxidants for biomimetic steroid hydroxylation in water

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 24, 2005, Pages 5463-5466

  Fang, Zhenglai ^a   Breslow, Ronald ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Cyclodextrin; Hydrophobic binding; Porphyrins

Indexed keywords

CYTOCHROME P450; HYDROGEN PEROXIDE; HYPOCHLORITE SODIUM; IODOSOBENZENE; OXIDIZING AGENT; STEROID; THIOL DERIVATIVE; WATER;

ARTICLE; BIOMIMETICS; CATALYST; CHEMICAL PROCEDURES; COVALENT BOND; OXIDATION; STEROID HYDROXYLATION;

CYTOCHROME P-450 ENZYME SYSTEM; HYDROGEN PEROXIDE; HYDROXYLATION; LIGANDS; OXIDANTS; SODIUM HYPOCHLORITE; STEROIDS; SULFHYDRYL COMPOUNDS; WATER;

EID: 27644481318     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.08.090     Document Type: Article

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