Overexpression of ADC2 in Arabidopsis induces dwarfism and late-flowering through GA deficiency

Plant Journal

Volumn 43, Issue 3, 2005, Pages 425-436

  Alcázar, Rubén ^a   García Martínez, José L ^b   Cuevas, Juan C ^a   Tiburcio, Antonio F ^a   Altabella, Teresa ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Ciudad Politécnica de la Innovación   (Spain)

Author keywords

ADC2; Arabidopsis; Dwarfism; Gibberellin; Late flowering; Putrescine

Indexed keywords

AMINES; BIOSYNTHESIS; ENZYMES; GENES; METABOLISM;

ARGININE DECARBOXYLASE (ADC); GENES ENCODING; MICROARRAY ANALYSIS;

PLANTS (BOTANY);

ARABIDOPSIS PROTEIN; ARGININE DECARBOXYLASE; CARBOXYLYASE; GIBBERELLIN; PUTRESCINE; SPERMIDINE; SPERMINE;

ARABIDOPSIS; ARTICLE; BIOSYNTHESIS; FLOWER; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHENOTYPE; PROTEIN MICROARRAY; TRANSGENIC PLANT;

ARABIDOPSIS; ARABIDOPSIS PROTEINS; CARBOXY-LYASES; FLOWERS; GENE EXPRESSION REGULATION, PLANT; GIBBERELLINS; PHENOTYPE; PLANTS, GENETICALLY MODIFIED; PROTEIN ARRAY ANALYSIS; PUTRESCINE; SPERMIDINE; SPERMINE;

BIOSYNTHESIS; ENZYMES; GENES; METABOLISM; PLANTS; POLYAMINES;

ARABIDOPSIS; ARABIDOPSIS THALIANA;

EID: 27644480426     PISSN: 09607412     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-313X.2005.02465.x     Document Type: Article

References (61)

1. Bassie, L., Noury, M., Lepri, O., Lahaye, T., Christou, P. and Capell, T. (2000) Promoter strength influences polyamine metabolism and morphogenic capacity in transgenic rice tissues expressing the oat adc cDNA constitutively. Transgenic Res. 9, 33-42.
2. Bevan, M. (1984) Binary Agrobacterium vectors for plant transformation. Nucleic Acids Res. 12, 8711-8721.
3. Bhatnagar, P., Glasheen, B.M., Bains, S.K., Long, S.L., Minocha, R., Walter, C. and Minocha, S.C. (2001) Transgenic manipulation of the metabolism of polyamines in poplar cells. Plant Physiol. 125, 2139-2153.
4. Bouchereau, A., Aziz, A., Larher, F. and Martin-Tanguy, J. (1999) Polyamines and environmental challenges: recent development. Plant Sci. 140, 103-125.
5. Bouquin, T., Meier, C., Foster, R., Nielsen, M.E. and Mundy, J. (2001) Control of specific gene expression by gibberellin and brassinosteroid. Plant Physiol. 127, 450-458.
6. Capell, T., Escobar, C., Liu, H., Burtin, D., Lepri, O. and Christou, P. (1998) Over-expression of the oat arginine decarboxylase cDNA in transgenic rice (Oryza sativa L.) affects normal development patterns in vitro and results in putrescine accumulation in transgenic plants. Theor. Appl. Genet. 97, 246-254.
7. Chang, K.S., Lee, S.H., Hwang, S.B. and Park, K.Y. (2000) Characterization and translational regulation of the arginine decarboxylase gene in carnation (Dianthus caryophyllus L.). Plant J. 24, 45-56.
8. Clough, S.J. and Bent, A.F. (1998) Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana. Plant J. 16, 735-743.
9. Cohen, S.S. (1998) A Guide to the Polyamines. New York: Oxford University Press.
10. Derkx, M.P.M., Vermeer, E. and Karssen, C.M. (1994) Gibberellins in seeds of Arabidopsis thaliana: biological activities, identification and effects of light and chilling on endogenous levels. Plant Growth Regul. 15, 223-234.
11. DeScenzo, R.A. and Minocha, S.C. (1993) Modulation of cellular polyamines in tobacco by transfer and expression of mouse ornithine decarboxylase cDNA. Plant Mol. Biol. 22, 113-127.
12. Feirer, R.P., Hocking, K.L. and Woods, P.J. (1998) Involvement of arginine decarboxylase in the response of Arabidopsis thaliana to osmotic stress. J. Plant Physiol. 153, 733-738.
13. García-Martínez, J.L., Santes, C., Croker, S.J. and Hedden, P. (1991) Identification, quantification and distribution of gibberellins in fruits of Pisum saticum L. cv. Alaska during pod development. Planta, 184, 53-60.
14. García-Martínez, J.L., Lopez-Díaz, I., Sánchez-Beltrán, M.J., Phillips, A.L., Ward, D.A., Gaskin, P. and Hedden, P. (1997) Isolation and transcript analysis of gibberellin 20-oxidase genes in pea and bean in relation to fruit development. Plant Mol. Biol. 33, 1073-1084.
15. Halmekytö, M., Alhonen, L., Alakuijala, L. and Janne, J. (1993) Transgenic mice over-producing putrescine in their tissues do not convert the diamine into higher polyamines. Biochem. J. 291, 505-508.
16. Hanfrey, C., Sommer, S., Mayer, M.J., Burtin, D. and Michael, A.J. (2001) Arabidopsis polyamine biosynthesis: absence of ornithine decarboxylase and the mechanism of arginine decarboxylase activity. Plant J. 27, 551-560.
17. Hanzawa, Y., Takahashi, T. and Komeda, Y. (1997) ACL5: an Arabidopsis gene required for internodal elongation after flowering. Plant J. 12, 863-874.
18. Hanzawa, Y., Takahashi, T., Michael, A.J., Burtin, D., Long, D., Pineiro, M., Coupland, G. and Komeda, Y. (2000) ACAULIS5, an Arabidopsis gene required for stem elongation, encodes a spermine synthase. EMBO J. 19, 4248-4256.
19. Hedden, P. and Kamiya, Y. (1997) Gibberellin biosynthesis: enzymes, genes and their regulation. Annu. Rev. Plant Physiol. Plant Mol. Biol. 48, 431-460.
20. Hedden, P. and Phillips, A.L (2000) Gibberellin metabolism: new insights revealed by the genes. Trends Plant Sci. 5, 523-530.
21. Hedden, P. and Proebsting, W.M. (1999) Genetic analysis of gibberellin biosynthesis. Plant Physiol. 119, 365-370.
22. Heljasvaara, R., Veress, I., Halmekyto, M., Alhonen, L., Janne, J., Laajala, P. and Pajunen, A. (1997) Transgenic mice overexpressing ornithine and S-adenosylmethionine decarboxylases maintain a physiological polyamine homeostasis in their tissues. Biochem. J. 323, 457-462.
23. Hiatt, A.C. and Malmberg, R.L. (1988) Utilization of putrescine in tobacco cell lines resistant to inhibitors of polyamine synthesis. Plant Physiol. 86, 441-446.
24. Imai, A., Akiyama, T., Kato, T., Sato, S., Tabata, S., Yamamoto, K.T. and Takahashi, T. (2004a) Spermine is not essential for survival of Arabidopsis. FEBS Lett. 556, 148-152.
25. Imai, A., Matsuyama, T., Hanzawa, Y. et al. (2004b) Spermidine synthase genes are essential for survival of Arabidopsis. Plant Physiol. 135, 1565-1573.
26. Janowitz, T., Kneifel, H. and Piotrowski, M. (2003) Identification and characterization of plant agmatine iminohydrolase, the last missing link in polyamine biosynthesis of plants. FEBS Lett. 544, 258-261.
27. Kauppinen, R.A. and Alhonen, L.I. (1995) Transgenic animals as models in the study of the neurobiological role of polyamines. Prog. Neurobiol. 47, 545-563.
28. 4 in vegetative shoots of Zea mays, Oryza sativa, and Arabidopsis thaliana. Plant Physiol. 102, 379-386.
29. Koornneef, M. and Vander Veen, J.H. (1980) Induction and analysis of gibberellin-sensitive mutants in Arabidopsis thaliana (L.) Heynh. Theor. Appl. Genet. 58, 257-263.
30. Kumar, A. and Minocha, S.C. (1998) Transgenic manipulation of polyamine metabolism. In Transgenic Plant Research (Lindsey, K., ed.). Amsterdam: Harwood, pp. 187-199.
31. Kumar, A., Taylor, M.A., Mad Arif, S.A. and Davis, H.V. (1996) Potato plants expressing antisense and sense SAMDC transgenes show altered levels of polyamines and ethylene: antisense plants display abnormal phenotypes. Plant J. 9, 147-158.
32. Kumar, A., Altabella, T., Taylor, M.R. and Tiburico, A.F. (1997) Recent advances in polyamine research. Trends Plant Sci. 2, 124-130.
33. Magome, H., Yamaguchi, S., Hanada, A., Kamiya, Y. and Oda, K. (2004) Dwarf and delayed-flowering 1, a novel Arabidopsis mutant deficient in gibberellin biosynthesis because of overexpression of a putative AP2 transcription factor. Plant J. 37, 720-729.
34. Malmberg, R.L., Watson, M.B., Galloway, G.L. and Yu, W. (1998) Molecular genetic analyses of plant polyamines. Crit. Rev. Plant Sci. 17, 199-224.
35. Marcé, M., Brown, D.S., Capell, T., Figueras, X. and Tiburcio, A.F. (1995) Rapid high-performance liquid Chromatographic method for quantitation of polyamines as their dansyl derivatives: application to plant and animal tissues. J. Chromatogr. B. Biomed. Appl. 666, 329-333.
36. Martin-Tanguy, J. (1997) Conjugated polyamines and reproductive development: biochemical, molecular and physiological approaches. Physiol. Plant. 100, 675-688.
37. Martin-Tanguy, J. (2001) Metabolism and function of polyamines in plants: recent development (new approaches). Plant Growth Regul. 34, 135-148.
38. Masgrau, C., Altabella, T., Farràs, R., Flores, D., Thompson, A.J., Besford, R.T. and Tiburcio, A.F. (1997) Inducible overexpression of oat arginine decarboxylase in transgenic tobacco plants. Plant J. 11, 465-473.
39. Minocha, R., Long, S., Magill, A.M., Aber, J. and McDowell, W.H. (2000) Foliar free polyamine and inorganic ion content in relation to soil and soil solution chemistry in two fertilized forest stands at the Harvard Forest, Massachusetts. Plant Soil, 222, 119-137.
40. Murashige, T. and Skoog, F. (1962) A revised medium for rapid growth and bioassays with tobacco tissue culture. Physiol. Plant. 15, 473-497.
41. Panicot, M., Masgrau, C., Borrell, A., Cordeiro, A., Tiburcio, A.F. and Altabella, T. (2002) Effects of putrescine accumulation in tobacco transgenic plants with different expression levels of oat arginine decarboxylase. Physiol. Plant. 114, 281-287.
42. Peirson, S.N., Butler, J.N. and Foster, R.G. (2003) Experimental validation of novel and conventional approaches to quantitative real-time PCR data analysis. Nucleic Acids Res. 31, e73.
43. Pérez-Amador, M.A., León, J., Green, P.J. and Carbonell, J. (2002) Induction of the arginine decarboxylase ADC2 gene provides evidence for the involvement of polyamines in the wound response in Arabidopsis. Plant Physiol. 130, 1454-1463.
44. Piotrowski, M., Janowitz, T. and Kneifel, H. (2003) Plant C-N hydrolases and the identification of a plant N-carbamoylputrescine amidohydrolase involved in polyamine biosynthesis. J. Biol. Chem. 278, 1708-1712.
45. Reichel, C., Mathur, J., Eckes, P., Langenkemper, K., Koncz, C., Schell, J., Reiss, B. and Maas, C. (1996) Enhanced green fluorescence by the expression of an Aequorea victoria green fluorescent protein mutant in mono- and dicotyledonous plant cells. Proc. Natl Acad. Sci. USA, 93, 5888-5893.
46. Rochester, D.E., Winer, J.A. and Shah, D.M. (1986) The structure and expression of maize genes encoding the major heat shock protein hsp70. EMBO J. 5, 451-458.
47. 1 biosynthesis in pea. Plant J. 21, 547-552.
48. Roy, M. and Wu, R. (2001) Arginine decarboxylase transgene expression and analysis of environmental stress tolerance in transgenic rice. Plant Sci. 160, 869-875.
49. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor: Cold Spring Harbor Laboratory Press.
50. Soyka, S. and Heyer, A.G. (1999) Arabidopsis knockout mutation of ADC2 reveals inducibility by osmotic stress. FEBS Lett. 458, 219-223.
51. Tabor, C.W. and Tabor, H. (1985) Polyamines in microorganisms. Microbiol. Rev. 49, 81-99.
52. Talón, M., Koornneef, M. and Zeevaart, J.A. (1990) Endogenous gibberellins in Arabidopsis thaliana and possible steps blocked in the biosynthetic pathways of the semidwarf ga4 and ga5 mutants. Proc. Natl Acad. Sci. USA, 87, 7983-7987.
53. Tassoni, A., van Buuren, M., Franceschetti, M., Fornalè, S. and Bagni, N. (2000) Polyamine content and metabolism in Arabidopsis thaliana and effect of spermidine on plant development. Plant Physiol. Biochem. 38, 383-393.
54. Tiburcio, A.F., Kaur-Sawhney, R. and Galston, A.W. (1988) Polyamine biosynthesis during vegetative and floral bud differentiation in thin layer tissue cultures. Plant Cell Physiol. 29, 1241-1249.
55. Tiburcio, A.F., Kaur-Sawhney, R. and Galston, A.W. (1990) Polyamine metabolism. In The Biochemistry of Plants, Intermediary Nitrogen Metabolism, Vol. 16 (Mifflin, B.J. and Lea, P.J., eds). New York: Academic Press, pp. 283-325.
56. Tiburcio, A.F., Altabella, T., Borrell, A. and Masgrau, C. (1997) Polyamine metabolism and its regulation. Physiol. Plant. 100, 664-674.
57. Tichopad, A., Dilger, M., Schwarz, G. and Pfaffl, M.W. (2003) Standardized determination of real-time PCR efficiency from a single reaction set-up. Nucleic Acids Res. 31, e122.
58. Urano, K., Yoshiba, Y., Nanjo, T., Igarashi, Y., Seki, M., Sekiguchi, F., Yamaguchi-Shinozaki, K. and Shinozaki, K. (2003) Characterization of Arabidopsis genes involved in biosynthesis of polyamines in abiotic stress responses and developmental stages. Plant Cell Environ. 26, 1917-1926.
59. Van Huizen, R., Ozga, J.A. and Reinecke, D.M. (1997) Seed and hormonal regulation of gibberellin 20-oxidase expression in pea pericarp. Plant Physiol. 115, 123-128.
60. Walden, R., Cordeiro, A. and Tiburcio, A.F. (1997) Polyamines: small molecules triggering pathways in plant growth and development. Plant Physiol. 113, 1009-1013.
61. Wilson, R.N., Heckman, J.W. and Somerville, C.R. (1992) Gibberellin is required for flowering in Arabidopsis thaliana under short days. Plant Physiol. 100, 403-408.