The Streptomyces lividans cytoplasmic signal recognition particle receptor FtsY is involved in protein secretion

Journal of Molecular Microbiology and Biotechnology

Volumn 9, Issue 1, 2005, Pages 57-62

  Palomino, Carmen ^a   Mellado, Rafael P ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

FtsY (SRP receptor); Protein secretion; Signal recognition particle; Streptomyces lividans

Indexed keywords

DOCKING PROTEIN; MEMBRANE PROTEIN; PEPTIDASE; TRANSLOCON;

ARTICLE; BACTERIAL STRAIN; BACTERIUM; CELL MEMBRANE; CYTOPLASM; GENETIC CODE; GRAM POSITIVE BACTERIUM; IMMUNOPRECIPITATION; MAMMAL; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN SECRETION; STREPTOMYCES LIVIDANS;

BACTERIAL PROTEINS; CELL MEMBRANE; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOPRECIPITATION; MODELS, BIOLOGICAL; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL RECOGNITION PARTICLE; STREPTOMYCES LIVIDANS;

BACTERIA (MICROORGANISMS); MAMMALIA; NEGIBACTERIA; POSIBACTERIA; STREPTOMYCES LIVIDANS;

EID: 27544503052     PISSN: 14641801     EISSN: None     Source Type: Journal    
DOI: 10.1159/000088147     Document Type: Article

References (22)

1. Angelini S, Deitermann S, Koch HG: FtsY, the bacterial signal recognition particle receptor, interacts functionally and physically with the SecYEG translocon. EMBO Rep 2005;6:1-6.
2. Beck K, Wu LF, Brunner J, Muller M: Discrimination between SRP- and SecA/SecB-dependent substrates involves selective recognition of nascent chains by SRP and trigger factor. EMBO J 2000;19:134-143.
3. Beha D, Deitermann S, Müller M, Koch HG: Export of beta-lactamase is independent of the signal recognition particle. J Biol Chem 2003;278:22161-22167.
4. Bibi E, Herskovits AA, Bochkareva E, Zelazny A: Putative integral membrane SRP receptors. Trends Biochem Sci 2001;26:15-16.
5. Bunai K, Takamatsu H, Horinaka T, Oguro A, Nakamura K, Yamane K: Bacillus subtilis Ffh, a homologue of mammalian SRP54, can intrinsically bind to the precursors of secretory proteins. Biochem Biophys Res Commun 1996;227:762-767.
6. Bunai K, Yamada K, Hayashi K, Nakamura K, Yamane K: Enhancing effect of Bacillus subtilis Ffh, a homologue of the SRP54 subunit of the mammalian signal recognition particle, on the binding of SecA to precursors of secretory proteins in vitro. J Biochem 1999;125:151-159.
7. Chater KF: Taking a genetic scalpel to the Streptomyces colony. Microbiology 1998;144:1465-1478.
8. Fekkes P, Driessen AJM: Protein targeting to the bacterial cytoplasmic membrane. Microbiol Mol Rev 1999;63:161-173.
9. Gilbert M, Morosoli R, Shareck F, Kluepfel D: Production and secretion of proteins by streptomycetes. Crit Rev Biotechnol 1995;15:13-39.
10. Hirose I, Sano K, Shioda I, Kumano M, Nakamura K, Yamane K: Proteome analysis of Bacillus subtilis extracellular proteins: a two-dimensional protein electrophoretic study. Microbiology 2000;146:65-75.
11. Nakamura K, Nishiguchi M, Honda K, Yamane K: The Bacillus subtilis SRP54 homologue, Ffh, has an intrinsic GTPases activity and forms a ribonucleoprotein complex with small cytoplasmic RNA in vivo. Biochem Biophys Res Commun 1994;199:1394-1399.
12. Oguro A, Kakeshita H, Honda K, Tkamatsu H, Nakamura K, Yamane K: srb: a Bacillus subtilis gene encoding a homologue of the alpha-subunit of the mammalian signal recognition particle receptor. DNA Res 1995;2:95-100.
13. Oguro A, Kakeshita H, Takamatsu H, Nakamura K, Yamane K: The effect of Srb, a homologue of the mammalian SRP receptor alpha-subunit, on Bacillus subtilis growth and protein translocation. Gene 1996;172:17-24.
14. Palacín A, de la Fuente R, Valle I, Rivas LA, Mellado RP: Streptomyces lividans contains a minimal functional signal recognition particle that is involved in protein secretion. Microbiology 2003;149:2435-2442.
15. Palacín A, Parro V, Geukens N, Anné J, Mellado RP: SipY is the Streptomyces lividans type I signal peptidase exerting a major effect on protein secretion. J Bacteriol 2002;184:4875-4880.
16. Rabindran SK, Haroun RI, Wisniewski J, Wu C: Regulation of heat shock factor trimer formation: role of a conserved leucine zipper. Science 1993;259:230-234.
17. Seluanov A, Bibi E: FtsY, the prokaryotic signal recognition particle receptor homologue is essential for biogenesis of membrane proteins. J Biol Chem 1997;272:2053-2055.
18. Song W, Raden D, Mandon E, Gilmore R: Role of Sec61α in the regulated transfer of the ribosome-nascent chain complex from the signal recognition particle to the translocation channel. Cell 2000;100:333-343.
19. Ulbrandt ND, Newitt JA, Bernstein HD: The E. coli signal recognition particle is required for the insertion of a subset of inner membrane proteins. Cell 1997;88:187-196.
20. Van Mellaert L, Anné J: Protein secretion in Gram-positive bacteria with high GC-content. Recent Res Dev Microbiol 1994;3:324-340.
21. van Wely KHM, Swaving J, Freudl R, Driessen AJM: 2001. Translocation of proteins across the cell envelope of Gram-positive bacteria. FEMS Microbiol Rev 2001;25:437-454.
22. Walter P, Johnson AE: Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane. Annu Rev Cell Biol 1994;10:87-119.