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Volumn 14, Issue 20, 2005, Pages 3047-3056

Juxtaposition of the HPFH2 enhancer is not sufficient to reactivate the γ-globin gene in adult erythropoiesis

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; DEOXYRIBONUCLEASE I; HEMOGLOBIN F;

EID: 27544485683     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddi337     Document Type: Article
Times cited : (4)

References (40)
  • 1
    • 0000831381 scopus 로고    scopus 로고
    • Hemoglobin switching
    • Stamatoyannopoulos, G., Majerus, P.W., Perlmutter, R.M. and Varmus, H. (eds), 3rd ed. W.B. Saunders Publishing Company, Philadelphia, PA
    • Stamatoyannopoulos, G. and Grosveld, F. (2001) Hemoglobin switching. In Stamatoyannopoulos, G., Majerus, P.W., Perlmutter, R.M. and Varmus, H. (eds), Molecular Basis of Blood Diseases. 3rd ed. W.B. Saunders Publishing Company, Philadelphia, PA, pp. 135-182.
    • (2001) Molecular Basis of Blood Diseases , pp. 135-182
    • Stamatoyannopoulos, G.1    Grosveld, F.2
  • 3
    • 0002128350 scopus 로고    scopus 로고
    • The Thalassemias
    • Stamatoyannopoulos, G., Majerus, P.W., Perlmutter, R.M. and Varmus, H. (eds), 3rd ed. W.B. Saunders Publishing Company, Philadelphia, PA
    • Weatherall, D.J. (2001) The Thalassemias. In Stamatoyannopoulos, G., Majerus, P.W., Perlmutter, R.M. and Varmus, H. (eds), Molecular Basis of Blood Diseases. 3rd ed. W.B. Saunders Publishing Company, Philadelphia, PA, pp. 183-226.
    • (2001) Molecular Basis of Blood Diseases , pp. 183-226
    • Weatherall, D.J.1
  • 4
    • 0024202810 scopus 로고
    • Globin gene expression in hereditary persistence of fetal haemoglobin and (delta beta) (0)-thalassaemia
    • Poncz, M., Henthorn, P., Stoeckert, C. and Surrey, S. (1988) Globin gene expression in hereditary persistence of fetal haemoglobin and (delta beta) (0)-thalassaemia. Oxf. Surv. Eukaryot. Genes, 5, 163-203.
    • (1988) Oxf. Surv. Eukaryot. Genes , vol.5 , pp. 163-203
    • Poncz, M.1    Henthorn, P.2    Stoeckert, C.3    Surrey, S.4
  • 5
    • 0029073038 scopus 로고
    • Use of yeast artificial chromosomes (YACs) in studies of mammalian development: Production of beta-globin locus YAC mice carrying human globin developmental mutants
    • Peterson, K.R., Li, Q.L., Clegg, C.H., Furukawa, T., Navas, P.A., Norton, E.J., Kimbrough, T.G. and Stamatoyannopoulos, G. (1995) Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants. Proc. Natl Acad. Sci. USA, 92, 5655-5659.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5655-5659
    • Peterson, K.R.1    Li, Q.L.2    Clegg, C.H.3    Furukawa, T.4    Navas, P.A.5    Norton, E.J.6    Kimbrough, T.G.7    Stamatoyannopoulos, G.8
  • 6
    • 0026649933 scopus 로고
    • A single point mutation is the cause of the Greek form of hereditary persistence of fetal haemoglobin
    • Berry, M., Grosveld, F. and Dillon, N. (1992) A single point mutation is the cause of the Greek form of hereditary persistence of fetal haemoglobin. Nature, 358, 499-502.
    • (1992) Nature , vol.358 , pp. 499-502
    • Berry, M.1    Grosveld, F.2    Dillon, N.3
  • 7
    • 0027443260 scopus 로고
    • Use of yeast artificial chromosomes (YACs) for studying control of gene expression: Correct regulation of the genes of a human beta-globin locus YAC following transfer to mouse erythroleukemia cell lines
    • Peterson, K.R., Zitnik, G., Huxley, C., Lowrey, C.H., Gnirke, A., Leppig, K.A., Papayannopoulou, T. and Stamatoyannopoulos, G. (1993) Use of yeast artificial chromosomes (YACs) for studying control of gene expression: Correct regulation of the genes of a human beta-globin locus YAC following transfer to mouse erythroleukemia cell lines. Proc. Natl Acad. Sci. USA, 90, 11207-11211.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11207-11211
    • Peterson, K.R.1    Zitnik, G.2    Huxley, C.3    Lowrey, C.H.4    Gnirke, A.5    Leppig, K.A.6    Papayannopoulou, T.7    Stamatoyannopoulos, G.8
  • 8
    • 0031863008 scopus 로고    scopus 로고
    • Developmental specificity of the interaction between the locus control region and embryonic or fetal globin genes in transgenic mice with an HS3 core deletion
    • Navas, P.A., Peterson, K.R., Li, Q., Skarpidi, E., Rohde, A., Shaw, S.E., Clegg, C.H., Asano, H. and Stamatoyannopoulos, G. (1998) Developmental specificity of the interaction between the locus control region and embryonic or fetal globin genes in transgenic mice with an HS3 core deletion. Mol. Cell. Biol., 18, 4188-4196.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 4188-4196
    • Navas, P.A.1    Peterson, K.R.2    Li, Q.3    Skarpidi, E.4    Rohde, A.5    Shaw, S.E.6    Clegg, C.H.7    Asano, H.8    Stamatoyannopoulos, G.9
  • 9
    • 1842344882 scopus 로고
    • Different 3′ end points of deletions causing delta beta-thalassemia and hereditary persistence of fetal hemoglobin: Implications for the control of gamma-globin gene expression in man
    • Tuan, D., Feingold, E., Newman, M., Weissman, S.M. and Forget, B.G. (1983) Different 3′ end points of deletions causing delta beta-thalassemia and hereditary persistence of fetal hemoglobin: implications for the control of gamma-globin gene expression in man. Proc. Natl Acad. Sci. USA, 80, 6937-6941.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 6937-6941
    • Tuan, D.1    Feingold, E.2    Newman, M.3    Weissman, S.M.4    Forget, B.G.5
  • 10
    • 0030895077 scopus 로고    scopus 로고
    • High levels of human gamma-globin gene expression in adult mice carrying a transgene of deletion-type hereditary persistence of fetal hemoglobin
    • Arcasoy, M.O., Romana, M., Fabry, M.E., Skarpidi, E., Nagel, R.L. and Forget, B.G. (1997) High levels of human gamma-globin gene expression in adult mice carrying a transgene of deletion-type hereditary persistence of fetal hemoglobin. Mol. Cell. Biol., 17, 2076-2089.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2076-2089
    • Arcasoy, M.O.1    Romana, M.2    Fabry, M.E.3    Skarpidi, E.4    Nagel, R.L.5    Forget, B.G.6
  • 12
    • 0024452772 scopus 로고
    • The breakpoint of a large deletion causing hereditary persistence of fetal hemoglobin occurs within an erythroid DNA domain remote from the beta-globin gene cluster
    • Feingold, E.A. and Forget, B.G. (1989) The breakpoint of a large deletion causing hereditary persistence of fetal hemoglobin occurs within an erythroid DNA domain remote from the beta-globin gene cluster. Blood, 74, 2178-2186.
    • (1989) Blood , vol.74 , pp. 2178-2186
    • Feingold, E.A.1    Forget, B.G.2
  • 13
    • 0142214623 scopus 로고    scopus 로고
    • Persistent gamma-globin expression in adult transgenic mice is mediated by HPFH-2, HPFH-3, and HPFH-6 breakpoint sequences
    • Katsantoni, E.Z., Langeveld, A., Wai, A.W., Drabek, D., Grosveld, F., Anagnou, N.P. and Strouboulis, J. (2003) Persistent gamma-globin expression in adult transgenic mice is mediated by HPFH-2, HPFH-3, and HPFH-6 breakpoint sequences. Blood, 102, 3412-3419.
    • (2003) Blood , vol.102 , pp. 3412-3419
    • Katsantoni, E.Z.1    Langeveld, A.2    Wai, A.W.3    Drabek, D.4    Grosveld, F.5    Anagnou, N.P.6    Strouboulis, J.7
  • 14
    • 0028918945 scopus 로고
    • Sequences located 3′ to the breakpoint of the hereditary persistence of fetal hemoglobin-3 deletion exhibit enhancer activity and can modify the developmental expression of the human fetal A gamma-globin gene in transgenic mice
    • Anagnou, N.P., Perez-Stable, C., Gelinas, R., Costantini, F., Liapaki, K., Constantopoulou, M., Kosteas, T., Moschonas, N.K. and Stamatoyannopoulos, G. (1995) Sequences located 3′ to the breakpoint of the hereditary persistence of fetal hemoglobin-3 deletion exhibit enhancer activity and can modify the developmental expression of the human fetal A gamma-globin gene in transgenic mice. J. Biol. Chem., 270, 10256-10263.
    • (1995) J. Biol. Chem. , vol.270 , pp. 10256-10263
    • Anagnou, N.P.1    Perez-Stable, C.2    Gelinas, R.3    Costantini, F.4    Liapaki, K.5    Constantopoulou, M.6    Kosteas, T.7    Moschonas, N.K.8    Stamatoyannopoulos, G.9
  • 15
    • 0033558362 scopus 로고    scopus 로고
    • Deletion of a region that is a candidate for the difference between the deletion forms of hereditary persistence of fetal hemoglobin and deltabeta-thalassemia affects beta- but not gamma-globin gene expression
    • Calzolari, R., McMorrow, T., Yannoutsos, N., Langeveld, A. and Grosveld, F. (1999) Deletion of a region that is a candidate for the difference between the deletion forms of hereditary persistence of fetal hemoglobin and deltabeta-thalassemia affects beta- but not gamma-globin gene expression. Embo. J., 18, 949-958.
    • (1999) Embo J. , vol.18 , pp. 949-958
    • Calzolari, R.1    McMorrow, T.2    Yannoutsos, N.3    Langeveld, A.4    Grosveld, F.5
  • 17
    • 0019312359 scopus 로고
    • Physical mapping of the globin gene deletion in hereditary persistence of foetal haemoglobin (HPFH)
    • Bernards, R. and Flavell, R.A. (1980) Physical mapping of the globin gene deletion in hereditary persistence of foetal haemoglobin (HPFH). Nucleic Acids Res., 8, 1521-1534.
    • (1980) Nucleic Acids Res. , vol.8 , pp. 1521-1534
    • Bernards, R.1    Flavell, R.A.2
  • 18
    • 0033853988 scopus 로고    scopus 로고
    • Intergenic transcription and developmental remodeling of chromatin subdomains in the human beta-globin locus
    • Gribnau, J., Diderich, K., Pruzina, S., Calzolari, R. and Fraser, P. (2000) Intergenic transcription and developmental remodeling of chromatin subdomains in the human beta-globin locus. Mol. Cell, 5, 377-386.
    • (2000) Mol. Cell , vol.5 , pp. 377-386
    • Gribnau, J.1    Diderich, K.2    Pruzina, S.3    Calzolari, R.4    Fraser, P.5
  • 20
    • 0033602445 scopus 로고    scopus 로고
    • Effects of altered gene order or orientation of the locus control region on human beta-globin gene expression in mice
    • Tanimoto, K., Liu, Q., Bungert, J. and Engel, J.D. (1999) Effects of altered gene order or orientation of the locus control region on human beta-globin gene expression in mice. Nature, 398, 344-348.
    • (1999) Nature , vol.398 , pp. 344-348
    • Tanimoto, K.1    Liu, Q.2    Bungert, J.3    Engel, J.D.4
  • 23
    • 7444246171 scopus 로고    scopus 로고
    • Transcriptional potentials of the beta-like globin genes at different developmental stages in transgenic mice and hemoglobin switching
    • Li, Q., Han, H., Ye, X., Stafford, M., Barkess, G. and Stamatoyannopoulos, G. (2004) Transcriptional potentials of the beta-like globin genes at different developmental stages in transgenic mice and hemoglobin switching. Blood Cells Mol. Dis., 33, 318-325.
    • (2004) Blood Cells Mol. Dis. , vol.33 , pp. 318-325
    • Li, Q.1    Han, H.2    Ye, X.3    Stafford, M.4    Barkess, G.5    Stamatoyannopoulos, G.6
  • 24
    • 0025891950 scopus 로고
    • Human gamma-globin genes silenced independently of other genes in the beta-globin locus
    • Dillon, N. and Grosveld, F. (1991) Human gamma-globin genes silenced independently of other genes in the beta-globin locus. Nature, 350, 252-254.
    • (1991) Nature , vol.350 , pp. 252-254
    • Dillon, N.1    Grosveld, F.2
  • 25
    • 0033231034 scopus 로고    scopus 로고
    • Transgenic analysis of a 100-kb human beta-globin cluster-containing DNA fragment propagated as a bacterial artificial chromosome
    • Kaufman, R.M., Pham, C.T. and Ley, T.J. (1999) Transgenic analysis of a 100-kb human beta-globin cluster-containing DNA fragment propagated as a bacterial artificial chromosome. Blood, 94, 3178-3184.
    • (1999) Blood , vol.94 , pp. 3178-3184
    • Kaufman, R.M.1    Pham, C.T.2    Ley, T.J.3
  • 26
    • 0030709312 scopus 로고    scopus 로고
    • The human beta globin locus introduced by YAC transfer exhibits a specific and reproducible pattern of developmental regulation in transgenic mice
    • Porcu, S., Kitamura, M., Witkowska, E., Zhang, Z., Mutero, A., Lin, C., Chang, J. and Gaensler, K.M. (1997) The human beta globin locus introduced by YAC transfer exhibits a specific and reproducible pattern of developmental regulation in transgenic mice. Blood, 90, 4602-4609.
    • (1997) Blood , vol.90 , pp. 4602-4609
    • Porcu, S.1    Kitamura, M.2    Witkowska, E.3    Zhang, Z.4    Mutero, A.5    Lin, C.6    Chang, J.7    Gaensler, K.M.8
  • 27
    • 0033861846 scopus 로고    scopus 로고
    • Beta-globin gene switching and DNase I sensitivity of the endogenous beta-globin locus in mice do not require the locus control region
    • Bender, M.A., Bulger, M., Close, J. and Groudine, M. (2000) Beta-globin gene switching and DNase I sensitivity of the endogenous beta-globin locus in mice do not require the locus control region. Mol. Cell, 5, 387-393.
    • (2000) Mol. Cell , vol.5 , pp. 387-393
    • Bender, M.A.1    Bulger, M.2    Close, J.3    Groudine, M.4
  • 29
    • 0026704374 scopus 로고
    • Inactivation of the human beta-globin gene by targeted insertion into the beta-globin locus control region
    • Kim, C.G., Epner, E.M., Forrester, W.C. and Groudine, M. (1992) Inactivation of the human beta-globin gene by targeted insertion into the beta-globin locus control region. Genes Dev., 6, 928-938.
    • (1992) Genes Dev. , vol.6 , pp. 928-938
    • Kim, C.G.1    Epner, E.M.2    Forrester, W.C.3    Groudine, M.4
  • 30
    • 0026516916 scopus 로고
    • Mechanism of DNase I hypersensitive site formation within the human globin locus control region
    • Lowrey, C.H., Bodine, D.M. and Nienhuis, A.W. (1992) Mechanism of DNase I hypersensitive site formation within the human globin locus control region. Proc. Natl Acad. Sci. USA, 89, 1143-1147.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1143-1147
    • Lowrey, C.H.1    Bodine, D.M.2    Nienhuis, A.W.3
  • 31
    • 0027174299 scopus 로고
    • An enhancer/locus control region is not sufficient to open chromatin
    • Reitman, M., Lee, E., Westphal, H. and Felsenfeld, G. (1993) An enhancer/ locus control region is not sufficient to open chromatin. Mol. Cell. Biol., 13, 3990-3998.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3990-3998
    • Reitman, M.1    Lee, E.2    Westphal, H.3    Felsenfeld, G.4
  • 32
    • 0034854577 scopus 로고    scopus 로고
    • Distinct mechanisms control RNA polymerase II recruitment to a tissue-specific locus control region and a downstream promoter
    • Johnson, K.D., Christensen, H.M., Zhao, B. and Bresnick, E.H. (2001) Distinct mechanisms control RNA polymerase II recruitment to a tissue-specific locus control region and a downstream promoter. Mol. Cell, 8, 465-471.
    • (2001) Mol. Cell , vol.8 , pp. 465-471
    • Johnson, K.D.1    Christensen, H.M.2    Zhao, B.3    Bresnick, E.H.4
  • 35
    • 23344450922 scopus 로고    scopus 로고
    • Synergistic and additive properties of the beta-globin LCR revealed by 5′HS3 deletion mutations: Implication for LCR chromatin architecture
    • Fang, X., Sun, J., Xiang, P., Yu, M., Navas, P.A., Peterson, K.R., Stamatoyannopoulos, G. and Li, Q. (2005) Synergistic and additive properties of the beta-globin LCR revealed by 5′HS3 deletion mutations: Implication for LCR chromatin architecture. Mol. Cell. Biol., 25, 7033-7041.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 7033-7041
    • Fang, X.1    Sun, J.2    Xiang, P.3    Yu, M.4    Navas, P.A.5    Peterson, K.R.6    Stamatoyannopoulos, G.7    Li, Q.8
  • 36
    • 0030826364 scopus 로고    scopus 로고
    • Intergenic transcription and transinduction of the human beta-globin locus
    • Ashe, H.L., Monks, J., Wijgerde, M., Fraser, P. and Proudfoot, N.J. (1997) Intergenic transcription and transinduction of the human beta-globin locus. Genes Dev., 11, 2494-2509.
    • (1997) Genes Dev. , vol.11 , pp. 2494-2509
    • Ashe, H.L.1    Monks, J.2    Wijgerde, M.3    Fraser, P.4    Proudfoot, N.J.5
  • 37
    • 0026482145 scopus 로고
    • Transcription of the hypersensitive site HS2 enhancer in erythroid cells
    • Tuan, D., Kong, S. and Hu, K. (1992) Transcription of the hypersensitive site HS2 enhancer in erythroid cells. Proc. Natl Acad. Sci. USA, 89, 11219-11223.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 11219-11223
    • Tuan, D.1    Kong, S.2    Hu, K.3
  • 38
    • 0028065129 scopus 로고
    • Position independence and proper developmental control of gamma-globin gene expression require both a 5′ locus control region and a downstream sequence element
    • Li, Q. and Stamatoyannopoulos, J.A. (1994) Position independence and proper developmental control of gamma-globin gene expression require both a 5′ locus control region and a downstream sequence element. Mol. Cell. Biol., 14, 6087-6096.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 6087-6096
    • Li, Q.1    Stamatoyannopoulos, J.A.2
  • 39
    • 0033569326 scopus 로고    scopus 로고
    • Structural analysis and mapping of DNase I hypersensitivity of HS5 of the beta-globin locus control region
    • Li, Q., Zhang, M., Duan, Z. and Stamatoyannopoulos, G. (1999) Structural analysis and mapping of DNase I hypersensitivity of HS5 of the beta-globin locus control region. Genomics, 61, 183-193.
    • (1999) Genomics , vol.61 , pp. 183-193
    • Li, Q.1    Zhang, M.2    Duan, Z.3    Stamatoyannopoulos, G.4
  • 40
    • 0037117575 scopus 로고    scopus 로고
    • Developmental specificity of recruitment of TBP to the TATA box of the human gamma-globin gene
    • Duan, Z.J., Fang, X., Rohde, A., Han, H., Stamatoyannopoulos, G. and Li, Q. (2002) Developmental specificity of recruitment of TBP to the TATA box of the human gamma-globin gene. Proc. Natl Acad. Sci. USA, 99, 5509-5514.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 5509-5514
    • Duan, Z.J.1    Fang, X.2    Rohde, A.3    Han, H.4    Stamatoyannopoulos, G.5    Li, Q.6


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