Parent-of-origin transmission of thrombophilic alleles to intrauterine growth-restricted newborns and transmission-ratio distortion in unaffected newborns

American Journal of Epidemiology

Volumn 162, Issue 9, 2005, Pages 891-897

  Infante Rivard, Claire ^a   Weinberg, Clarice R ^b  

^a MCGILL UNIVERSITY   (Canada)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Alleles; Factor XIII; Fetal development; Fetal growth retardation; Genomic imprinting; Polymorphism, genetic; Thrombophilia

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); BLOOD CLOTTING FACTOR 13; BLOOD CLOTTING FACTOR 5 LEIDEN; LEUCINE; PROTHROMBIN; VALINE;

HEALTH AND DISEASE;

ALLELE; ARTICLE; BIRTH WEIGHT; DISEASE TRANSMISSION; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOME IMPRINTING; GESTATIONAL AGE; HUMAN; INTRAUTERINE GROWTH RETARDATION; MAJOR CLINICAL STUDY; MALE; NEWBORN; SEGREGATION DISTORTION; SURVIVAL; THROMBOPHILIA;

ALLELES; CANADA; CASE-CONTROL STUDIES; FACTOR V; FEMALE; FETAL GROWTH RETARDATION; GENOMIC IMPRINTING; HUMANS; INFANT, NEWBORN; INFANT, SMALL FOR GESTATIONAL AGE; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); POLYMORPHISM, GENETIC; PROTHROMBIN;

EID: 27544473743     PISSN: 00029262     EISSN: 14766256     Source Type: Journal    
DOI: 10.1093/aje/kwi293     Document Type: Article

References (29)

1. American College of Obstetricians and Gynecologists. Intrauterine growth restriction. Clinical management guidelines for obstetrician-gynecologists. Int J Gynaecol Obstet 2001;72:85-96.
2. Barker DJP. Fetal programming of coronary heart disease. Trends Endocrinol Metabol 2002;13:364-68.
3. Infante-Rivard C, Lévy E, Rivard GE, et al. Small babies receive the cardiovascular protective apolipoprotein 2 allele less frequently than expected. J Med Genet 2003;40:626-9.
4. Tripodi A, Mannucci PM. Laboratory investigation of thrombophilia. Clin Chem 2001;47:1597-606.
5. Lane DA, Grant PJ. Role of hemostatic gene polymorphisms in venous and arterial thrombotic disease. Blood 2000;95:1517-32.
6. Nordt TK, Lohrmann J, Bode C. Regulation of PAI-1 expression by genetic polymorphisms: impact on atherogenesis. Thromb Res 2001;103(suppl 1):S1-5.
7. Ariëns RAS, Philippou H, Nagaswami C, et al. The factor XIII V34L polymorphism accelerates thrombin activation of factor XIII and affects cross-linked fibrin structure. Blood 2000;96:988-95.
8. Alexander BT. Placental insufficiency leads to development of hypertension in growth-restricted offspring. Hypertension 2003;41:457-62.
9. Infante-Rivard C, Rivard GE, Yotov WV, et al. Absence of association of thrombophilia polymorphisms with intrauterine growth restriction. N Engl J Med 2002;347:19-25.
10. Infante-Rivard C, Rivard GE, Guiguet M, et al. Thrombophilic polymorphisms and intrauterine growth restriction. Epidemiology 2005;16:281-7.
11. Hitchins MP, Moore GE. Genomic imprinting in fetal growth and development. Expert Rev Mol Med 2002;May 9:1-19. (http://www.expertreviews.org/ 0200457Xh.htm).
12. Costancia M, Kelsey G, Reik W. Resourceful imprinting. Nature 2004;432:53-7.
13. Wilkins JF, Haig D. What good is genomic imprinting: the function of parent-specific gene expression. Nat Rev Genet 2003;4:359-68.
14. Naumova AK, Greenwood CMT, Morgan K. Imprinting and deviation from Mendelian transmission ratios. Genome 2001;44:311-20.
15. Zöllner S, Wen X, Hanchard NA, et al. Evidence for extensive transmission distortion in the human genome. Am J Hum Genet 2004;74:62-72.
16. Arbuckle TE, Wilkins R, Sherman GJ. Birth weight percentiles by gestational age in Canada. Obstet Gynecol 1993;81:39-48.
17. Elbaz A, Poirier O, Canaple S, et al. The association between the Val34Leu polymorphism in the factor XIII gene and brain infarction. The GÉNIC Investigators. Blood 2000;95:586-91.
18. Anderson JL, Muhlestein JB, Habashi J, et al. Lack of association of a common polymorphism of the plasminogen activator inhibitor-1 gene with coronary artery disease and myocardial infarction. J Am Coll Cardiol 1999;34:1778-83.
19. Dawson SJ, Wiman B, Hamsten A, et al. The two allele sequences of a common polymorphism in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene respond differently to interleukin-1 in HepG2 cells. J Biol Chem 1993;268:10739-45.
20. Weinberg CR. Methods for detection of parent-of-origin effects in genetic studies of case-parents triads. Am J Hum Gen 1999;66:229-35.
21. Weinberg CR, Wilcox AJ, Lie RT. A log-linear approach to case-parent triad data: assessing effects of disease genes that act either directly or through maternal effects and that may be subject to parental imprinting. Am J Hum Genet 1998;62:969-78.
22. van den Oord EJCG, Vermunt JK. Testing for linkage disequilibrium, maternal effects, and imprinting with (in)complete case-parent triads, by use of the program LEM. Am J Hum Gen 2000;66:335-8.
23. Sinsheimer JS, Palmer CGS, Woodward JA. The maternal-fetal genotype incompatibility test: detecting genotype combinations that increase risk for disease. Genet Epidemiol 2003;24:1-13.
24. Ariëns RAS, Lai TS, Weisel JW, et al. Role of factor XIII in fibrin clot formation and effects of genetic polymorphisms. Blood 2002;100:743-54.
25. Sobel BE, Taatjes DJ, Schneider DJ. Intramural plasminogen activator inhibitor type-1 and coronary atherosclerosis. Arterioscler Thromb Vasc Biol 2003;23:1979-89.
26. Haig D, Westoby M. Parent-specific gene expression and the triploid endosperm. Am Nat 1989;134:147-55.
27. Le Stunff C, Fallin D, Bougnères P. Paternal transmission of the very common class I INS VNTR alleles predisposes to childhood obesity. Nat Genet 2001;29:96-9.
28. Greer IA. Thrombophilia: implications for pregnancy outcome. Thromb Res 2003;109:73-81.
29. Isotalo PA, Wells GA, Donnelly JG. Neonatal and fetal methylenetetrahydrofolate reductase genetic polymorphisms: an examination of C677Tand A1298C mutations. Am J Hum Genet 2000;67:986-90.