Diode or tunnel-diode characteristics? Resolving the catalytic consequences of proton coupled electron transfer in a multi-centered oxidoreductase

Journal of the American Chemical Society

Volumn 127, Issue 43, 2005, Pages 14964-14965

  Gwyer, James D ^a   Richardson, David J ^a   Butt, Julea N ^a  

^a UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

OXIDOREDUCTASE;

ARTICLE; CATALYSIS; CRYSTALLIZATION; DIODE; ELECTROCHEMISTRY; ELECTRON TRANSPORT; ENZYME ACTIVE SITE; ENZYME ACTIVITY; MOLECULAR INTERACTION; OXIDATION REDUCTION REACTION; POTENTIOMETRY;

CATALYSIS; CYTOCHROME C GROUP; CYTOCHROMES A1; CYTOCHROMES C1; ELECTRON SPIN RESONANCE SPECTROSCOPY; ELECTRON TRANSPORT; ESCHERICHIA COLI; HYDROGEN-ION CONCENTRATION; MODELS, BIOLOGICAL; NITRATE REDUCTASES; OXIDATION-REDUCTION; OXIDOREDUCTASES; PROTONS;

EID: 27544467818     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja054160s     Document Type: Article

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11. This analogy is made due to the similar current-potential characteristics of the systems. To date, PFV has failed to detect catalytic oxidation by nitrite reductase. Thus, net current flow through the enzyme appears unidirectional, and diodes show a similar propensity to support substantial currents in one direction only. Tunnel-diodes show a region of negative resistance to this flow of current, as seen in the current-profile of nitrite reductase at pH 8 but not at pH 4. Streetman, B. G. Solid State Electronic Devices, 2nd ed.; Prentice-Hall: New Jersey, 1980.
12. H+.
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