Antibiotic prescribing in response to bacterial isolates in the Intensive Care Unit

Anaesthesia and Intensive Care

Volumn 33, Issue 5, 2005, Pages 571-577

  Buising, K L ^a   Thursky, K A ^a   Bak, N ^a   Skull, S ^a   Street, A ^a   Presneill, J J ^a   Cade, J F ^a   Brown, G V ^a  

^a ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

Adult; Antibiotics; Drug utilization; Intensive care unit; Therapeutics

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC AGENT; CEFTRIAXONE; CEPHALOSPORIN DERIVATIVE; IMIPENEM; METICILLIN; PENICILLIN DERIVATIVE; VANCOMYCIN;

ACCESS TO INFORMATION; ACINETOBACTER; ADOLESCENT; ADULT; AGED; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTICLE; AUSTRALIA; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; COHORT ANALYSIS; CONTROLLED STUDY; DECISION SUPPORT SYSTEM; DRUG EFFICACY; ENTEROBACTERIACEAE; ENTEROCOCCUS; FEMALE; HOSPITAL ADMISSION; HOSPITAL INFECTION; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; PRESCRIPTION; PROSPECTIVE STUDY; PSEUDOMONAS; STAPHYLOCOCCUS AUREUS; STENOTROPHOMONAS; SURGICAL INFECTION; VENTILATOR ASSOCIATED PNEUMONIA;

EID: 27544464162     PISSN: 0310057X     EISSN: None     Source Type: Journal    
DOI: 10.1177/0310057x0503300504     Document Type: Article

References (35)

1. Alberti C, Brun-Buisson C, Burchardi H et al. Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study. Intensive Care Med 2002; 28:108-121.
2. Richards M, Thursky K, Buising K. Epidemiology of ICU infections; Sites, prevalence and risk factors. Sem Resp Crit Care Med 2003; 24:3-23.
3. Dupont H, Mentec H, Sollet JP, Bleichner G. Impact of appropriateness of initial antibiotic therapy on the outcome of ventilator-associated pneumonia. Intensive Care Med 2001; 27:355-362.
4. Leibovici L, Shraga I, Drucker M et al. The benefit of appropriate empirical antibiotic treatment in patients with bloodstream infection. J Intern Med 1998; 244:379-386.
5. Kollef MH. Inadequate antimicrobial treatment: an important determinant of outcome for hospitalized patients. Clin Infect Dis 2000; 31, Suppl 4:S131-138.
6. Fridkin SK. Increasing prevalence of antimicrobial resistance in intensive care units. Crit Care Med 2001; 29(Suppl 4):N64-68.
7. Gaynes R. The impact of antimicrobial use on the emergence of antimicrobial- resistant bacteria in hospitals. Infect Dis Clin North Am 1997; 11:757-765.
8. Fridkin SK, Edwards JR, Courval JM et al. The effect of vancomycin and third-generation cephalosporins on prevalence of vancomycin-resistant enterococci in 126 U.S. adult intensive care units. Ann Intern Med 2001; 135:175-183.
9. Fridkin SY, Edwards JR, Tenover FC et al. Antimicrobial resistance prevalence rates in hospital antibiograms reflect prevalence rates among pathogens associated with hospital-acquired infections. Clin Infect Dis 2001; 33:324-330.
10. Demey HE, Jansens H, Van Laer F et al. Strategies for selecting antibiotics in intensive care units. Clin Microbiol Infect 1999; 5 Suppl 1:S29-S34.
11. http://www.cdc.gov/drugresistance/healthcare/ha/12steps_HA_htm Accessed July 19, 2005
12. Bellomo R, Bersten AD, Boots RJ et al. The use of antimicrobials in ten Australian and New Zealand intensive care units Anaesth Intensive Care 1998; 26:648-653.
13. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992; 20:864-874.
14. US Department of Health and Human Services CfDCaP. NNIS Manual; 1994.
15. StataCorp. Stata Statistical Software. In. Release 6.0 ed. College Station, TX: Stata Corporation; 1997.
16. Chamot E, Boffi El Amari E, Rohner P, Van Delden C. Effectiveness of combination antimicrobial therapy for Pseudomonas aeruginosa bacteremia. Antimicrob Agents Chemother 2003; 47:2756-2764.
17. Endimiani A, Tamborini A, Luzzaro F, Lombardi G, Toniolo A. A two-year analysis of risk factors and outcome in patients with bloodstream infection. Jpn J Infect Dis 2003; 56:1-7.
18. Ibrahim EH, Sherman G, Ward S, Fraser VJ, Kollef MH. The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting. Chest 2000; 118:146-155.
19. Kang CI, Kim SH, Kim HB et al. Pseudomonas aeruginosa bacteremia: risk factors for mortality and influence of delayed receipt of effective antimicrobial therapy on clinical outcome. Clin Infect Dis 2003; 37:745-751.
20. Leone M, Bourgoin A, Cambon S et al. Empirical antimicrobial therapy of septic shock patients: adequacy and impact on the outcome. Crit Care Med 2003; 31:462-467.
21. Kollef MH, Sherman G, Ward S, Fraser VJ. Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients. Chest 1999; 115:462-474.
22. Zaragoza R, Artero A, Camarena JJ et al. The influence of inadequate empirical antimicrobial treatment on patients with bloodstream infections in an intensive care unit. Clin Microbiol Infect 2003; 9:412-418.
23. McGowan JE, Jr. Increasing threat of Gram-positive bacterial infections in the intensive care unit setting. Crit Care Med 2001; 29(Suppl 4):N69-74.
24. Allegranzi B, Luzzati R, Luzzani A et al. Impact of antibiotic changes in empirical therapy on antimicrobial resistance in intensive care unit-acquired infections. J Hosp Infect 2002; 52:136-140.
25. Archibald L, Phillips L, Monnet D et al. Antimicrobial resistance in isolates from inpatients and outpatients in the United States: increasing importance of the intensive care unit. Clin Infect Dis 1997; 24:211-215.
26. Kollef MH. Optimizing antibiotic therapy in the intensive care unit setting. Crit Care 2001; 5:189-195.
27. Bergmans DC, Bonten MJ, Gaillard CA et al. Indications for antibiotic use in ICU patients: a one-year prospective surveillance. J Antimicrob Chemother 1997; 39:527-535.
28. Vincent JL, Bihari DJ, Suter PM et al. The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee. JAMA 1995; 274:639-644.
29. Leibovici L, Gitelman V, Yehezkelli Y, et al. Improving empirical antibiotic treatment: prospective, nonintervention testing of a decision support system. J Intern Med 1997; 242:395-400.
30. Rintala E, Kairisto V, Eerola E et al. Antimicrobial therapy of septicemic patients in intensive care units before and after blood culture reporting. Scand J Infect Dis 1991; 23:341-346.
31. Sintchenko V, Iredell JR, Gilbert GL, Coiera E. What do physicians think about evidence-based antibiotic use in critical care? A survey of Australian intensivists and infectious disease practitioners. Intern Med J 2001; 31:462-469.
32. Fluckiger U, Zimmerli W, Sax H, Frei R, Widmer AF. Clinical impact of an infectious disease service on the management of bloodstream infection. Eur J Clin Microbiol Infect Dis 2000; 19:493-500.
33. Evans RS, Pestotnik SL, Classen DC et al. A computer-assisted management program for antibiotics and other antiinfective agents. N Engl J Med 1998; 338:232-238.
34. Bailey TC, Troy McMullin S. Using information systems technology to improve antibiotic prescribing. Crit Care Med 2001; 29(Suppl 4):N87-91.
35. Watson DA. Antibiotic guidelines: improved implementation is the challenge. Med J Aust 2002; 176:513-514.