Double dioxygenation by mouse 8S-lipoxygenase: Specific formation of a potent peroxisome proliferator-activated receptor α agonist

Biochemical and Biophysical Research Communications

Volumn 338, Issue 1, 2005, Pages 136-143

  Jisaka, Mitsuo ^a   Iwanaga, Chitose ^a   Takahashi, Nobuyuki ^b   Goto, Tsuyoshi ^b   Kawada, Teruo ^b   Yamamoto, Tatsuyuki ^a   Ikeda, Izumi ^a   Nishimura, Kohji ^a   Nagaya, Tsutomu ^a   Fushiki, Tohru ^b   Yokota, Kazushige ^a  

^a SHIMANE UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

15S Lipoxygenase 2; 8S Lipoxygenase; 1H NMR; Arachidonic acid; Bacterial expression; DiHPETE; Kinetics; Multifunction; PPAR

Indexed keywords

8 HYDROXYPEROXYEICOSATETRAENOIC ACID; 8,15 DIHYDROPEROXYARACHIDONIC ACID; ARACHIDONATE 8 LIPOXYGENASE; ARACHIDONIC ACID DERIVATIVE; LIPOXYGENASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; UNCLASSIFIED DRUG;

AGONIST; ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; CATALYSIS; CONTROLLED STUDY; DEOXYGENATION; ENZYME ACTIVATION; ENZYME METABOLISM; ENZYME PURIFICATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; SUBSTITUTION REACTION;

ANIMALS; ARACHIDONATE 15-LIPOXYGENASE; HUMANS; HYDROXYEICOSATETRAENOIC ACIDS; KINETICS; LIPOXYGENASE; MICE; OXYGEN; PPAR ALPHA; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 27544463883     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.08.029     Document Type: Article

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