Neural mechanisms of hyperalgesia after tissue injury

Johns Hopkins APL Technical Digest (Applied Physics Laboratory)

Volumn 26, Issue 1, 2005, Pages 56-66

  Meyer, Richard A ^a,b,c   Ringkamp, Matthias ^d   Campbell, James N ^d,e,f   Raja, Srinivasa N ^g,h  

^a APL   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Research Committee   (United States)

^d Medical School   (United States)

^e Blaustein Pain Treatment Center   (United States)

^f American Pain Foundation   (United States)

^g Department of Anesthesiology   (United States)

^h Department of Anesthesiology

Author keywords

[No Author keywords available]

Indexed keywords

CENTRAL NERVOUS SYSTEM; HYPERALGESIA; PAIN SENSATION; TISSUE INJURY;

DISEASES; PATIENT TREATMENT; TISSUE;

NEUROLOGY;

EID: 27544457701     PISSN: 02705214     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Ali, Z., Meyer, R. A., and Campbell, J. N., "Secondary Hyperalgesia to Mechanical but Nut Heat Stimuli Following a Capsaicin Injection in Hairy Skin," Pain 68(2-3), 401-411 (1996).
2. Raja, S. N., Campbell, J. N., and Meyer, R. A., "Evidence for Different Mechanisms of Primary and Secondary Hyperalgesia Following Heat Injury to the Glabrous Skin," Brain 107, 1179-1188 (1984).
3. Meyer, R. A., and Campbell, J. N., "Myelinated Nociceptive Afferents Account for the Hyperalgesia That Follows a Burn to the Hand," Science 213, 1527-1529 (1981).
4. Meyer, R. A., Walker, R. E., and Mountcastle, V. B., "A Laser Stimulator for the Study of Cutaneous Thermal Pain Sensation," IEEE Trans. Biomed. Eng. 23, 54-60 (1976).
5. Davis, K. D., Meyer, R. A., Turnquist, J. L., Filloon, T. G., Pappagallo, M., and Campbell, J. N., "Cutaneous Injection of the Capsaicin Analog, NE-21610, Produces Analgesia to Heat but Not to Mechanical Stimuli in Man," Pain 62, 17-26 (1995).
6. Meyer, R. A., and Campbell, J. N., "Peripheral Neural Coding of Pain Sensation," Johns Hopkins APL Tech. Dig. 2, 164-171 (1981).
7. Peng, Y. B., Ringkamp, M., Meyer, R. A., and Campbell, J. N., "Fatigue and Paradoxical Enhancement of Heat Response in C-Fiber Nociceptors from Cross-Modal Excitation," J. Neurosci. 23(11), 4766-4774 (2003).
8. Campbell, J. N., Khan, A. A., Meyer, R. A., and Raja, S. N., "Responses to Heat of C-Fiber Nociceptors in Monkey Are Altered by Injury in the Receptive Field but Not by Adjacent Injury," Pain 32, 327-332 (1988).
9. Schmelz, M., Schmidt, R., Ringkamp, M., Forster, C., Handwerker, H. O., and Torebjörk, H. E., "Limitation of Sensitization to Injured Parts of Receptive Fields in Human Skin C-Nociceptors," Exp. Brain Res. 109(1), 141-147 (1996).
10. LaMotte, R. H., Shain, C. N., Simone, D. A., and Tsai, E.-F.P., "Neurogenic Hyperalgesia: Psychophysical Studies of Underlying Mechanisms," J. Neurophysiol. 66, 190-211 (1991).
11. Magerl, W., Fuchs, P. N., Meyer, R. A., and Treede, R-D., "Roles of Capsaicin-Insensitive Nociceptors in Cutaneous Pain and Secondary Hyperalgesia," Brain 124(Pt. 9), 1754-1764 (2001).
12. Schneider, W., Slugg, R. M., Turnquist, B. P., Meyer, R. A., and Campbell, J. N., "An Electromechanical Stimulator System for Neurophysiological and Psychophysical Studies of Pain," J. Neurosci. Methods 60, 61-68 (1995).
13. Slugg, R. M., Meyer, R. A., and Campbell, J. N., "Response of Cutaneous A- and C-Fiber Nociceptors in the Monkey to Controlled-Force Stimuli," J. Neurophysiol. 83(4), 2179-2191 (2000).
14. Nolano, M., Simone, D. A., Wendelschafer-Crabb, G., Johnson, T., Hazen, E., and Kennedy, W. R., "Topical Capsaicin in Humans: Parallel Loss of Epidermal Nerve Fibers and Pain Sensation," Pain 81(1-2), 135-145 (1999).
15. Fuchs, P. N., Campbell, J. N., and Meyer, R. A., "Secondary Hyperalgesia Persists in Capsaicin Desensitized Skin," Pain 84(2-3), 141-149 (2000).
16. Ziegler, E. A., Magerl, W., Meyer, R. A., and Treede, R-D., "Secondary Hyperalgesia to Punctate Mechanical Stimuli: Central Sensitization to A-Fibre Nociceptor Input," Brain 122(Pt. 12), 2245-2257 (1999).