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Volumn 33, Issue 11, 2005, Pages 1717-1722

Role of CYP2E1 in deramciclane metabolism

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2E1; DERAMCICLANE FUMARATE; DIETHYLTHIOCARBAMATE; ISONIAZID;

EID: 27544446293     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.105.003772     Document Type: Article
Times cited : (5)

References (20)
  • 2
    • 0042480445 scopus 로고
    • Psychopharmacology of a new anxiolytic agent EGYT-3886
    • Gacsályi I, Gyertyán I, Petöcz L, and Budai Z (1988) Psychopharmacology of a new anxiolytic agent EGYT-3886. Pharmacol Res Commun 20 (Suppl I):115-116.
    • (1988) Pharmacol Res Commun , vol.20 , Issue.1 SUPPL. , pp. 115-116
    • Gacsályi, I.1    Gyertyán, I.2    Petöcz, L.3    Budai, Z.4
  • 3
    • 0026035519 scopus 로고
    • Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight suspects
    • Guengerich FP, Kim D-H, and Iwasaki M (1991) Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight suspects. Chem Res Toxicol 4:168-179.
    • (1991) Chem Res Toxicol , vol.4 , pp. 168-179
    • Guengerich, F.P.1    Kim, D.-H.2    Iwasaki, M.3
  • 4
    • 0024418697 scopus 로고
    • The specificity of inhibition of debrisoquine 4-hydoxylase activity by quinidine and quinine in the rat is the inverse of that in man
    • Kobayashi S, Murray S, Watson D, Sesardic D, Davies DS, and Boobis AR (1989) The specificity of inhibition of debrisoquine 4-hydoxylase activity by quinidine and quinine in the rat is the inverse of that in man. Biochem Pharmacol 38:2795-2799.
    • (1989) Biochem Pharmacol , vol.38 , pp. 2795-2799
    • Kobayashi, S.1    Murray, S.2    Watson, D.3    Sesardic, D.4    Davies, D.S.5    Boobis, A.R.6
  • 5
    • 0024511395 scopus 로고
    • Inhibition of high-affinity synaptosomal uptake of γ-aminobutyric acid by a bicyclo-heptane derivative
    • Kovács I, Maksay G, and Simonyi M (1989) Inhibition of high-affinity synaptosomal uptake of γ-aminobutyric acid by a bicyclo-heptane derivative. Arzneim-Forsch/Drug Res 39:295-297.
    • (1989) Arzneim-Forsch/Drug Res , vol.39 , pp. 295-297
    • Kovács, I.1    Maksay, G.2    Simonyi, M.3
  • 6
    • 1542407204 scopus 로고    scopus 로고
    • Effect of the novel anxiolytic drug deramciclane on cytochrome P450 2D6 activity as measured by desipramine pharmacokinetics
    • Laine K, De Bruyn S, Björklund H, Rouru J, Hanninen J, Scheinin H, and Anttila M (2004) Effect of the novel anxiolytic drug deramciclane on cytochrome P450 2D6 activity as measured by desipramine pharmacokinetics. Eur J Clin Pharmacol 59:893-898.
    • (2004) Eur J Clin Pharmacol , vol.59 , pp. 893-898
    • Laine, K.1    De Bruyn, S.2    Björklund, H.3    Rouru, J.4    Hanninen, J.5    Scheinin, H.6    Anttila, M.7
  • 9
    • 0001415920 scopus 로고    scopus 로고
    • Drug metabolizing enzymes
    • Maurel P (1998) Drug metabolizing enzymes. Curr Opin Crit Care 4:213-218.
    • (1998) Curr Opin Crit Care , vol.4 , pp. 213-218
    • Maurel, P.1
  • 10
    • 0023873591 scopus 로고
    • Tolbutamide hydroxylation by human liver microsomes. Kinetic characterisation and relationship to other cytochrome P450 dependent xenobiotic oxidations
    • Miners JO, Smith KJ, Robson RA, McManus ME, Veronese ME, and Birkett DJ (1988) Tolbutamide hydroxylation by human liver microsomes. Kinetic characterisation and relationship to other cytochrome P450 dependent xenobiotic oxidations. Biochem Pharmacol 37:1137-1144.
    • (1988) Biochem Pharmacol , vol.37 , pp. 1137-1144
    • Miners, J.O.1    Smith, K.J.2    Robson, R.A.3    McManus, M.E.4    Veronese, M.E.5    Birkett, D.J.6
  • 12
    • 0030056594 scopus 로고    scopus 로고
    • Specificity of substrates and inhibitor probes for cytochrome P450s: Evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes
    • Ono S, Hatanaka T, Hotta H, Satoh T, Gonzalez FJ, and Tsutsui M (1996) Specificity of substrates and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes. Xenobiotica 26:681-693.
    • (1996) Xenobiotica , vol.26 , pp. 681-693
    • Ono, S.1    Hatanaka, T.2    Hotta, H.3    Satoh, T.4    Gonzalez, F.J.5    Tsutsui, M.6
  • 14
    • 0022117289 scopus 로고
    • p-Nitrophenol hydroxylation: A microsomal oxidation which is highly inducible by ethanol
    • Reinke LA and Moyer MJ (1985) p-Nitrophenol hydroxylation: a microsomal oxidation which is highly inducible by ethanol. Drug Metab Dispos 13:548-552.
    • (1985) Drug Metab Dispos , vol.13 , pp. 548-552
    • Reinke, L.A.1    Moyer, M.J.2
  • 15
    • 0030834058 scopus 로고    scopus 로고
    • Human cytochrome P450 enzymes: A status report summarizing their reactions, substrates, inducers and inhibitors
    • Rendic S and Di Carlo FJ (1997) Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers and inhibitors. Drug Metab Rev 29:413-580.
    • (1997) Drug Metab Rev , vol.29 , pp. 413-580
    • Rendic, S.1    Di Carlo, F.J.2
  • 16
    • 0027281051 scopus 로고
    • Formation of ligand and metabolite complexes as a means for selective quantitation of cytochrome P450 isozymes
    • Roos PH, Golub-Ciosk B, Kallweit P, Kauczinski D, and Hanstein WG (1993) Formation of ligand and metabolite complexes as a means for selective quantitation of cytochrome P450 isozymes. Biochem Pharmacol 45:2239-2250.
    • (1993) Biochem Pharmacol , vol.45 , pp. 2239-2250
    • Roos, P.H.1    Golub-Ciosk, B.2    Kallweit, P.3    Kauczinski, D.4    Hanstein, W.G.5
  • 18
    • 0028842375 scopus 로고
    • Heterogenous effects of natural flavonoids on monooxygenase activities in human and rat liver microsomes
    • Siess M-H, Leclerc J, Canivenc-Lavier M-C, Rat P, and Suschetet M (1995) Heterogenous effects of natural flavonoids on monooxygenase activities in human and rat liver microsomes. Toxicol Appl Pharmacol 130:73-78.
    • (1995) Toxicol Appl Pharmacol , vol.130 , pp. 73-78
    • Siess, M.-H.1    Leclerc, J.2    Canivenc-Lavier, M.-C.3    Rat, P.4    Suschetet, M.5
  • 19
    • 0041662013 scopus 로고    scopus 로고
    • Some aspects of interindividual variations in the metabolism of xenobiotics
    • Tamási V, Vereczkey L, Falus A, and Monostory K (2003) Some aspects of interindividual variations in the metabolism of xenobiotics. Inflamm Res 52:322-333.
    • (2003) Inflamm Res , vol.52 , pp. 322-333
    • Tamási, V.1    Vereczkey, L.2    Falus, A.3    Monostory, K.4
  • 20
    • 0016174577 scopus 로고
    • Preparation and properties of partially purified cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase from rabbit liver microsomes
    • van der Hoeven TA and Coon MJ (1974) Preparation and properties of partially purified cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase from rabbit liver microsomes. J Biol Chem 249:6302-6310.
    • (1974) J Biol Chem , vol.249 , pp. 6302-6310
    • Van Der Hoeven, T.A.1    Coon, M.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.