Creation of a P450 array toward high-throughput analysis

Analytical Chemistry

Volumn 77, Issue 21, 2005, Pages 7080-7083

  Sakai Kato, Kumiko ^a   Kato, Masaru ^b,c   Homma, Hiroshi ^d   Toyo'oka, Toshimasa ^b   Utsunomiya Tate, Naoko ^a  

^a MUSASHINO UNIVERSITY   (Japan)

^b UNIVERSITY OF SHIZUOKA   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d KITASATO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ENTITIES; DRUG DISCOVERY; HIGH-THROUGHPUT ANALYSIS; METABOLIC REACTION;

DRUG PRODUCTS; METABOLISM; MIXTURES; REACTION KINETICS; SILICA; THROUGHPUT;

PROTEINS;

CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 3A4; ETHOXYRESORUFIN; FLUORESCEIN; FLUORESCEIN DERIVATIVE; ISOENZYME; NANOPARTICLE; RESORUFIN; SILICATE; SILICON DIOXIDE; TESTOSTERONE; TESTOSTERONE DERIVATIVE;

AQUEOUS SOLUTION; ARTICLE; ASSAY; ENZYME ACTIVITY; ENZYME IMMOBILIZATION; FILM; FLUORESCENCE; GEL; HIGH THROUGHPUT SCREENING; HUMAN; HYDROGEL; METABOLISM; MICROASSAY; MICROSOME; TRANSMISSION ELECTRON MICROSCOPY;

CYTOCHROME P-450 ENZYME SYSTEM; ENZYMES, IMMOBILIZED; HUMANS; MICROSOMES; PROTEIN ARRAY ANALYSIS; SUBSTRATE SPECIFICITY;

EID: 27544432578     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac050714y     Document Type: Article

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