Isolation and synthesis of a new aromatic compound, brefelamide, from Dictyostelium cellular slime molds and its inhibitory effect on the proliferation of astrocytoma cells

Journal of Organic Chemistry

Volumn 70, Issue 22, 2005, Pages 8854-8858

  Kikuchi, Haruhisa ^a   Saito, Yoshinori ^a   Sekiya, Jun'ichi ^a   Okano, Yumiko ^a   Saito, Masaki ^a   Nakahata, Norimichi ^a   Kubohara, Yuzuru ^b   Oshima, Yoshiteru ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b GUNMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DRUG PRODUCTS; METABOLITES; METHANOL; NUCLEAR MAGNETIC RESONANCE; STRUCTURE (COMPOSITION); SYNTHESIS (CHEMICAL);

ASTROCYTOMA CELLS; BREFELAMIDE; DICTYOSTELIUM CELLULAR SLIME MOLDS; DRUG DEVELOPMENT;

AROMATIC COMPOUNDS;

AROMATIC COMPOUND; BREFELAMIDE; EREBUSINONE; UNCLASSIFIED DRUG;

ARTICLE; ASTROCYTOMA CELL; BIOSYNTHESIS; CARBON NUCLEAR MAGNETIC RESONANCE; CELL CYCLE; CELL PROLIFERATION; CHEMICAL STRUCTURE; DICTYOSTELIUM; DRUG ISOLATION; ELECTROSPRAY MASS SPECTROMETRY; FRUITING BODY; GROWTH INHIBITION; HUMAN; HUMAN CELL; MOULD; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE;

AMIDES; ANIMALS; ASTROCYTOMA; CELL LINE, TUMOR; CELL PROLIFERATION; DICTYOSTELIIDA; DICTYOSTELIUM; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PHENOLS;

EID: 27444447651     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo051352x     Document Type: Article

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