Advances in diabetes for the millennium: Toward a cure for diabetes CME

MedGenMed Medscape General Medicine

Volumn 6, Issue 3 SUPPL., 2004, Pages

  Vinik, Aaron I ^b   Pittenger, Gary ^a   Fishwick, David Taylor ^a  

^a Strelitz Diabetes Research Institutes   (United States)

^b EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN; GLUCOKINASE; GLUCOSE TRANSPORTER 2; HEXOKINASE; IMMUNOSUPPRESSIVE AGENT; INSULIN; INTERLEUKIN 2 RECEPTOR ANTIBODY; LECTIN; LYMPHOCYTE ANTIBODY; MONOCLONAL ANTIBODY; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; RAPAMYCIN; STEROID; STREPTOZOCIN; TACROLIMUS;

ARTIFICIAL PANCREAS; AUTOIMMUNITY; BIOMEDICAL ENGINEERING; BONE MARROW TOXICITY; CELL FUNCTION; CELL PROTECTION; CELL TRANSPLANTATION; CONTINUING EDUCATION; DIABETES MELLITUS; DRUG MECHANISM; FUTUROLOGY; GASTROINTESTINAL TOXICITY; GRAFT REJECTION; HUMAN; MEDICAL EDUCATION; NEPHROTOXICITY; PANCREAS ISLET BETA CELL; PANCREAS TRANSPLANTATION; REVIEW; TREATMENT PLANNING; PANCREAS ISLET TRANSPLANTATION;

DIABETES MELLITUS; HUMANS; ISLETS OF LANGERHANS TRANSPLANTATION; PANCREAS TRANSPLANTATION;

EID: 27444440380     PISSN: None     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (19)

1. Sutherland DE, Gruessner RW, Dunn DL, et al. Lessons learned from more than 1,000 pancreas transplants at a single institution. Ann Surg. 2001;233:463-501.
2. Ciancio G, Miller J, Burke GW. The use of intravenous tacrolimus and mycophenolate mofetil as induction and maintenance immunosuppression in simultaneous pancreas -- kidney recipients with previous transplants. Clin Transplant. 2001;15:142-145.
3. Mele TS, Halloran PF. The use of mycophenolate mofetil in transplant recipients. Immunopharmacology. 2000;47:215-245.
4. Plosker GL, Foster RH. Tacrolimus: a further update of its pharmacology and therapeutic use in the management of organ transplantation. Drugs. 2000;59:323-389.
5. Tang AW, Walker RG, Nicholls KM, Becker GJ. Sirolimus does not potentiate indices of chronic cyclosporin nephrotoxicity. Transplant Proc. 2001;33:1061-1063.
6. Hesse UJ, Troisi R, Jacobs B, et al. A single center's clinical experience with quadruple immunosuppression including ATG or IL2 antibodies and mycophenolate mofetil in simultaneous pancreas-kidney transplants. Clin Transplant. 2000;14:340-344.
7. Sun Y, Ma X, Zhou D, Vacek I, Sun AM. Normalization of diabetes in spontaneously diabetic cynomologus monkeys by xenografts of microencapsulated porcine islets without immunosuppression. J Clin Invest. 1996;98:1417-1422.
8. Suzuki K, Bonner-Weir S, Trivedi N, et al. Function and survival of macroencapsulated syngeneic islets transplanted into streptozocin-diabetic mice. Transplantation. 1998;66:21-28.
9. Shapiro AMJ, Lakey JRT, Ryan EA, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med. 2000;343:230-238.
10. Ryan EA, Lakey JRT, Rajotte RV, et al. Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. Diabetes. 2001;50:710-719.
11. Bouwens L, Kloppel G. Islet cell neogenesis in the pancreas. Virchows Arch. 1996;427:553-560.
12. Wilkin TJ. Neogenesis of islet cells. Diabetes Metab Rev. 1998;14:331-333.
13. Al-Abdullah IH, Ayala T, Panigrahi D, Kumar RM, Kumar MS. Neogenesis of pancreatic endocrine cells in copper-deprived rat models. Pancreas. 2000;21:63-68.
14. Bonner-Weir S. Beta-cell turnover: its assessment and implications. Diabetes. 2001;50(suppl1):S20-S24.
15. Cheung AT, Dayanandan B, Lewis JT, et al. Glucose-dependent insulin release from genetically engineered K cells. Science. 2000;290:1959-1962.
16. Lee HC, Kim SJ, Kim KS, Shin HC, Yoon JW. Remission in models of type 1 diabetes by gene therapy using a single-chain insulin analogue. Nature. 2000;408:483-488.
17. Daniloff GY. Continuous glucose monitoring: long-term implantable sensor approach. Diabetes Technol Ther. 1999;1:261-266.
18. Kobayashi S, Akiyama T, Nata K, et al. Identification of a receptor for reg (regenerating gene) protein, a pancreatic beta-cell regeneration factor. J Biol Chem. 2000;275:10723-10726.
19. Rafaeloff R, Pittenger GL, Barlow SW, et al. Cloning and sequencing of the pancreatic islet neogenesis associated protein (INGAP) gene and its expression in islet neogenesis in hamsters. J Clin Invest. 1997;99:2100-2109.