Monitoring urinary orosomucoid in acute inflammation: Observations on urinary excretion of orosomucoid, albumin, α1-microglobulin, and IgG

Clinical Chemistry

Volumn 51, Issue 11, 2005, Pages 2052-2058

  Magid, Erik ^a   Guldager, Henrik ^a   Hesse, Dan ^a   Christiansen, Merete Skovdal ^a  

^a AMAGER HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; ALPHA 1 MICROGLOBULIN; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CREATINE; IMMUNOGLOBULIN G; OROSOMUCOID;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DISEASE MARKER; FEMALE; HUMAN; INFLAMMATION; MALE; MONITORING; PATHOPHYSIOLOGY; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEINURIA; QUANTITATIVE ANALYSIS; REFERENCE VALUE; SEPSIS; TURBIDIMETRY; URINALYSIS; URINARY EXCRETION;

ACUTE DISEASE; AGED; AGED, 80 AND OVER; ALBUMINS; ALPHA-GLOBULINS; C-REACTIVE PROTEIN; FEMALE; HUMANS; IMMUNOASSAY; IMMUNOGLOBULIN G; INFLAMMATION; MALE; MIDDLE AGED; NEPHELOMETRY AND TURBIDIMETRY; OROSOMUCOID; POSTOPERATIVE COMPLICATIONS; PROTEINURIA; REFERENCE VALUES; SEPSIS;

EID: 27444439927     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2005.055442     Document Type: Article

References (40)

1. Jensen H, Henriksen K. Proteinuria in non-renal infectious diseases. Acta Med Scand 1974;196:75-82.
2. Gosling P, Sutcliffe AJ. Proteinuria following trauma. Ann Clin Biochem 1986;23(Pt 6):681-5.
3. Shearman CP, Gosling P, Walker KJ. Is low proteinuria an early predictor of severity of acute pancreatitis? J Clin Pathol 1989;42:1132-5.
4. Wood PR, Gosling P, Cook MC. Microalbuminuria following anaphylaxis with general anaesthesia. Br J Anaesth 2000;84:808-10.
5. Poortmans J, Haralambie G. Biochemical changes in a 100 km run: proteins in serum and urine. Eur J Appl Physiol 1979;40:245-54.
6. Pang JX, Ginanni N, Dongre AR, Hefta SA, Opitek GJ. Biomarker discovery in urine by proteomics. J Proteome Res 2002;1:161-9.
7. Waller KV, Ward KM, Mahan JD, Wismatt DK. Current concepts in proteinuria. Clin Chem 1989;35:755-65.
8. Gosling P, Brudney S, McGrath L, Riseboro S, Manji M. Mortality prediction at admission to intensive care: a comparison of microalbuminuria with acute physiology scores after 24 hours. Crit Care Med 2003;31:98-103.
9. Molnar Z, Szakmany T, Heigl P. Microalbuminuria does not reflect increased systemic capillary permeability in septic shock. Intensive Care Med 2003;29:391-5.
10. Molnar Z, Szakmany T, Koszegi T. Prophylactic N-acetylcysteine decreases serum CRP but not PCT levels and microalbuminuria following major abdominal surgery: a prospective, randomised, double-blinded, placebo-controlled clinical trial. Intensive Care Med 2003;29:749-55.
11. Weber MH, Verwiebe R. Alpha 1-microglobulin (protein HC): features of a promising indicator of proximal tubular dysfunction. Eur J Clin Chem Clin Biochem 1992;30:683-91.
12. Yu H, Yanagisawa Y, Forbes MA, Cooper EH, Crockson RA, MacLennan IC. Alpha-1-microglobulin: an indicator protein for renal tubular function. J Clin Pathol 1983;36:253-9.
13. Fournier T, Medjoubi N, Porquet D. Alpha-1-acid glycoprotein. Biochim Biophys Acta 2000;1482:157-71.
14. Haraldsson B, Rippe B. Orosomucoid as one of the serum components contributing to normal capillary permselectivity in rat skeletal muscle. Acta Physiol Scand 1987;129:127-35.
15. Nielsen SH, Jensen JE, Magid E. Episodic albuminuria in acute ischaemic heart disease. Lancet 1994;343:732.
16. Nielsen SH, Petersen JS, Magid E. Albuminuria in ischemic heart disease. Scand J Clin Lab Invest Suppl 1999;230:143-52.
17. Christiansen MS, Hommel E, Magid E, Feldt-Rasmussen B. Orosomucoid in urine predicts cardiovascular and over-all mortality in patients with type II diabetes. Diabetologia 2002;45:115-20.
18. Christiansen MS, Hommel E, Magid E, Feldt-Rasmussen B. Orosomucoid in urine is a powerful predictor of cardiovascular mortality in normoalbuminuric patients with type 2 diabetes at five years of follow-up. Diabetologia 2005;48:386-93.
19. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference Committee. Chest 1992;101:1644-55.
20. Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med 1985;13:818-29.
21. Christiansen MS, Blirup-Jensen S, Foged L, Larsen M, Magid E. A particle-enhanced turbidimetric immunoassay for quantitative determination of orosomucoid in urine: development, validation and reference values. Clin Chem Lab Med 2004;42:1168-77.
22. Mogensen CE, Keane WF, Bennett PH, Jerums G, Parving HH, Passa P, et al. Prevention of diabetic renal disease with special reference to microalbuminuria. Lancet 1995;346:1080-4.
23. Thorevska N, Sabahi R, Upadya A, Manthous C, Amoateng-Adjepong Y. Microalbuminuria in critically ill medical patients: prevalence, predictors, and prognostic significance. Crit Care Med 2003;31:1075-81.
24. De Gaudio AR, Spina R, Di Filippo A, Feri M. Glomerular permeability and trauma: a correlation between microalbuminuria and injury severity score. Crit Care Med 1999;27:2105-8.
25. MacKinnon KL, Molnar Z, Lowe D, Watson ID, Shearer E. Use of microalbuminuria as a predictor of outcome in critically ill patients. Br J Anaesth 2000;84:239-41.
26. Szakmany T, Molnar Z. Increased glomerular permeability and pulmonary dysfunction following major surgery: correlation of microalbuminuria and PaO/FiO ratio. Acta Anaesthesiol Scand 2004;48:704-10.
27. Poortmans JR, Engels MF, Sellier M, Leclercq R. Urine protein excretion and swimming events. Med Sci Sports Exerc 1991;23:831-5.
28. Dziedzic T, Slowik A, Szczudlik A. Urine albumin excretion in acute ischaemic stroke is related to serum interleukin-6. Clin Chem Lab Med 2004;42:182-5.
29. Pedersen LM, Bergmann OJ. Urinary albumin excretion and its relationship to C-reactive protein and proinflammatory cytokines in patients with cancer and febrile neutropenia. Scand J Infect Dis 2003;35:491-4.
30. Pedersen LM, Sorensen PG. Mediators of inflammation correlate with microalbuminuria in patients with non-Hodgkin's lymphoma. Br J Haematol 2003;121:275-9.
31. Pedersen BK, Steensberg A, Fischer C, Keller C, Keller P, Plomgaard P, et al. Searching for the exercise factor: is IL-6 a candidate? J Muscle Res Cell Motil 2003;24:113-9.
32. Eiskjaer H, Mogensen CE, Schmitz A, Pedersen EB. Enhanced urinary excretion of albumin and β2 microglobulin in essential hypertension induced by atrial natriuretic peptide. Scand J Clin Lab Invest 1991;51:359-66.
33. McCarthy ET, Sharma R, Sharma M, Li JZ, Ge XL, Dileezpan KN, et al. TNF-α increases albumin permeability of isolated rat glomeruli through the generation of superoxide. J Am Soc Nephrol 1998;9:433-8.
34. Deen WM, Lazzara MJ. Glomerular filtration of albumin: how small Is the sieving coefficient? Kidney Int Suppl 2004;S63-S64.
35. Haraldsson B, Sorensson J. Why do we not all have proteinuria? An update of our current understanding of the glomerular barrier. News Physiol Sci 2004;19:7-10.
36. Russo LM, Osicka TM, Brammar GC, Candido R, Jerums G, Comper WD. Renal processing of albumin in diabetes and hypertension in rats: possible role of TGF-β1. Am J Nephrol 2003;23:61-70.
37. Carrigan SD, Scott G, Tabrizian M. Toward resolving the challenges of sepsis diagnosis. Clin Chem 2004;50:1301-14.
38. Paisley KE, Beaman M, Tooke JE, Mohamed-Ali V, Lowe GD, Shore AC. Endothelial dysfunction and inflammation in asymptomatic proteinuria. Kidney Int 2003;63:624-33.
39. Stehouwer CD, Gall MA, Twisk JW, Knudsen E, Emeis JJ, Parving HH. Increased urinary albumin excretion, endothelial dysfunction, and chronic low-grade inflammation in type 2 diabetes: progressive, interrelated, and independently associated with risk of death. Diabetes 2002;51:1157-65.
40. Tencer J, Thysell H, Grubb A. Analysis of proteinuria: reference limits for urine excretion of albumin, protein HC, immunoglobulin G, kappa- and lambda-immunoreactivity, orosomucoid and α1-antitrypsin. Scand J Clin Lab Invest 1996;56:691-700.