Salivary sIgA and cortisol: Markers for functional dependence in older adults

Special Care in Dentistry

Volumn 25, Issue 5, 2005, Pages 242-252

  Lawrence, Herenia P ^a   Fillery, Edward D ^a   Matear, David W ^a,b   Paterson, Leslie ^a   Hawkins, Robert J ^a   Locker, David ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b BAYCREST CENTRE FOR GERIATRIC CARE   (Canada)

Author keywords

Activities of daily living; Aged; Functional ability; Functional dependence; Nutrition; Psychological stress; Saliva; Salivary cortisol; Secretory immunoglobulin A

Indexed keywords

EID: 27344460547     PISSN: 02751879     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1754-4505.2005.tb01657.x     Document Type: Article

References (60)

1. Statistics Canada. Statistical report on the health of Canadians. Ottawa, ON: Minister of Supply and Services, 1999. Available at www.stat-can.ca/ english/freepub/82-570-XIE/parta.htm
2. National Institute on Aging, National Institutes of Health (NIH). Aging America poses unprecedented challenge, says new census, Aging Institute report. Bethesda, MD: National Institute on Aging, NIH, Press Release Archive, May 20, 1996. Available at www.nia.nih.gov/news/pr/1996/05-20.htm
3. Hubert HB, Bloch DA, Oehlert JW, Fries JF. Lifestyle habits and compression of morbidity. J Gerontol A Biol Sci Med Sci 2002; 57:347-51.
4. Jette AM, Feldman HA, Douglass C. Oral disease and physical disability in community-dwelling older persons. J Am Geriatr Soc 1993; 41:1102-8.
5. Mojon P, Rentsch A, Budtz-Jørgensen E, Baehni PC. Effects of an oral health program on selected clinical parameters and salivary bacteria in a long-term care facility. Eur J Oral Sci 1998; 106:827-34.
6. Avlund K, Holm-Pedersen P, Schroll M. Functional ability and oral health among older people: a longitudinal study from age 75 to 80. J Am Geriatr Soc 2001; 49:954-62.
7. Shimazaki Y, Soh I, Saito T, Yamashita Y, Koga T, Miyazaki H, Takehara T. Influence of dentition status on physical disability, mental impairment, and mortality in institutionalized elderly people. J Dent Res 2001; 80:340-5.
8. Morishita M, Takaesu Y, Miyatake K, Shinsho F, Fujioka M. Oral health care status of homebound elderly in Japan. J Oral Rehab 2001; 28:717-20.
9. Nordenram G, Ljunggren G. Oral status, cognitive and functional capacity versus oral treatment need in nursing home residents: a comparison between assessments by dental and ward staff. Oral Dis 2002; 8:296-302.
10. Avlund K, Holm-Pedersen P, Morse DE, Viitanen M, Winblad B. Tooth loss and caries prevalence in very old Swedish people: the relationship to cognitive function and functional ability. Gerodontology 2004; 21:17-26.
11. Dwyer JT, Coleman KA, Krall E, et al. Changes in relative weight among institutionalized elderly adults. J Gerontol 1987; 42:246-51.
12. Sullivan DH, Patch GA, Walls RC, Lipschitz DA. Impact of nutrition status on morbidity and mortality in a select population of geriatric rehabilitation patients. Am J Clin Nutr 1990; 51:749-58.
13. Guigoz Y, Vellas B, Garry PJ. Assessing the nutritional status of the elderly: the Mini Nutritional Assessment as part of the geriatric evaluation. Nutr Rev 1996; 54:S59-65.
14. Incalzi RA, Capparella O, Gemma A, et al. Inadequate caloric intake: a risk factor for mortality of geriatric patients in the acute-care hospital. Age Ageing 1998; 27:303-10.
15. Griep M, Mets T, Collys K, Ponjaert-Kristoffersen I, Massart D. Risk of malnutrition in retirement homes elderly persons measured by the "mini-nutritional assessment". J Gerontol 2000; 55:57-63.
16. Mestecky J. Saliva as a manifestation of the common mucosal immune system. Ann N Y Acad Sci 1993; 694:184-94.
17. Williams RC, Gibbons RJ. Inhibition of bacterial adherence by secretory immunoglobulin A: a mechanism of antigen disposal. Science 1972; 177:697-9.
18. Mestecky J, Russell MW. Mucosal immunoglobulins and their contribution to defense mechanisms: an overview (review). Biochem Soc Trans 1997; 25:457-62.
19. Brandtzaeg P, Farstad IN, Johansen FE, Morion HC, Norderhaug IN, Yamanaka T. The B-cell system of human mucosae and exocrine glands (review). Immunol Rev 1999; 171:45-87.
20. Epstein JB, Kimura LH, Menard TW, Truelove EL, Pearsall NN. Effects of specific antibodies on the interaction between the fungus Candida albicans and human oral mucosa. Arch Oral Biol 1982; 27:469-74.
21. Vudhichamnong K, Walker DM, Ryley HC. The effect of secretory immunoglobulin A on the in-vitro adherence of the yeast Candida albicans to human oral epithelial cells. Arch Oral Biol 1982; 27:617-21.
22. Smith DJ, Taubman MA, Ebersole JL. Ontogeny and senescence of salivary immunity. J Dent Res 1987; 66:451-6.
23. Butler JE, Spradling JE, Peterman JH, Joshi KS, Satam M, Challacombe SJ. Humoral immunity in root caries in an elderly population. I. Oral Microbiol Immunol 1990; 5:98-107.
24. Butler JE, Spradling JE, Rowat J, Ekstrand J, Challacombe SJ. Humoral immunity in root caries in an elderly population. II. Oral Microbiol Immunol 1990; 5:113-20.
25. Smith DJ, Joshipura K, Kent R, Taubman MA. Effect of age on immunoglobulin content and volume of human labial gland saliva. J Dent Res 1992; 71:1891-4.
26. Tenovuo J. Oral defense factors in the elderly (review). Endod Dent Traumatol 1992; 8:93-8.
27. Challacombe SJ. Immunologic aspects of oral candidiasis. Oral Surg Oral Med Oral Pathol 1994; 78:202-10.
28. Challacombe SJ, Percival RS, Marsh PD. Age-related changes in immunoglobulin isotypes in whole and parotid saliva and serum in healthy individuals. Oral Microbiol Immunol 1995; 10:202-7.
29. Närhi TO, Tenovuo J, Ainamo A, Vilja P. Antimicrobial factors, sialic acid, and protein concentration in whole saliva of the elderly. Scand J Dent Res 1994; 102:120-5.
30. Percival RS, Marsh PD, Challacombe SJ. Age-related changes in salivary antibodies to commensal oral and gut biota. Oral Microhiol Immunol 1997; 12:57-63.
31. Pajukoski H, Meurman JH, Snellman-Gröhn S, Keinänen S, Sulkava R. Salivary flow and composition in elderly patients referred to an acute care geriatric ward. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997; 84:265-71.
32. Lockhart SR, Joly S, Vargas K, Swails-Wenger J, Enger L, Soll DR. Natural defenses against Candida colonization breakdown in the oral cavities of the elderly. J Dent Res 1999; 78:857-68.
33. Jeganathan S, Ufomata D, Hobkirk JA, Ivanyi L. Immunoglobulin A1 and A2 subclass of salivary antibodies to Candida albicans in patients with oral candidosis. Clin Exp Immunol 1987; 70:316-21.
34. Ahl T, Reinholdt J. Subclass distribution of salivary secretory immunoglobulin A antibodies to oral streptococci. Infect Immunity 1991; 59:3619-25.
35. Denny PC, Denny PA, Klauser DK, Hong SH, Navazesh M, Tabak LA. Age-related changes in mucins from whole saliva. J Dent Res 1991; 70:1320-7.
36. Navazesh M, Mulligan RA, Kipnis V, Denny PA, Denny PC. Comparison of whole saliva flow rates and mucin concentrations in healthy Caucasian young and aged adults. J Dent Res 1992; 71:1275-8.
37. Valdimarsdottir HB, Stone AA. Psychosocial factors and secretory immunoglobulin A (review). Crit Rev Oral Biol Med 1997; 8:461-74.
38. Henningsen GM, Hurrell JJ Jr Baker F, Douglas C, MacKenzie BA, Robertson SK, Phipps FC. Measurement of salivary immunoglobulin A as an immunologic biomarker of job stress. Scand J Work Environ Health 1992; 18(Suppl 2):133-6.
39. Yang Y, Koh D, Ng V, Lee CY, Chan G, Dong F, Goh SH, Anantharaman V, Chia SE. Self perceived work related stress and the relation with salivary IgA and lysozyme among emergency department nurses. Occup Environ Med 2002; 59:836-41.
40. Bosch JA, Brand HS, Ligtenberg TJ, Bermond B, Hoogstraten J, Nieuw Amerongen AV. Psychological stress as a determinant of protein levels and salivary-induced aggregation of Streptococcus gordonii in human whole saliva. Psychosom Med 1996; 58:374-82.
41. Esterling BA, Kiecolt-Glaser JK, Glaser R. Psychosocial modulation of cytokine-induced natural killer cell activity in older adults. Psychosom Med 1996; 58:264-72.
42. Schulz P, Kirschbaum C, Prüssner J, Hellhammer D. Increased free cortisol secretion after awakening in chronically stressed individuals due to work overload. Stress Med 1998; 14:91-7.
43. Kirschbaum C, Read GF, Hellhammer DH. Assessment of Hormones and Drugs in Saliva in Biobehavioral Research. Seattle: Hogrefe & Huber; 1993.
44. Locker D, Matcar D, Stephens M, Lawrence H, Payne B. Comparison of the GOHAI and OHIP-14 as measures of the oral health-related quality of life of the elderly. Communilv Dent Oral Epidemiol 2001; 29:373-81.
45. Katz RV. Assessing root caries in populations: the evaluation of the Root Caries Index. J Public Health Dent 1980; 40:7-16.
46. Proctor GB, Carpenter GH. Chewing stimulates secretion of human salivary secretory immunoglobulin A. J Dent Res 2001; 80:909-13.
47. Fitzsimmons SP, Evans MK, Pearce CL, Sheridan MJ, Wientzen R, Cole MF. Immunoglobulin A subclasses in infants' saliva and in saliva and milk from their mothers. J Pediatr 1994; 124:566-73.
48. Cole MF, Bryan S, Evans MK, Pearce CL, Sheridan MJ, Sura PA, Wientzen RL, Bowden GH. Humoral immunity to commensal oral bacteria in human infants: salivary secretory immunoglobulin A antibodies reactive with Streptococcus mitis biovar 1, Streptococcus oralis, Streptococcus mutans, and Enterococcus faecalis during the first two years of life. Infect Immun 1999; 67:1878-86
49. Bosy A, Fillery ED. Correlations of microbiological and clinical data from a halitosis clinic population. Abstract presented at the 5th International Society for Breath Odor Research (ISBOR) Conference, Tokyo, Japan July 1-2, 2001. Available at www.dent.niigata-u.ac.jp/ICBO/
50. Dormenval V, Budtz-Jørgensen E, Mojon P, Bruyere A, Rapin C-H. Nutrition, general health status and oral health status in hospitalised elders. Gerodontology 1995; 12:73-80.
51. Katz S, Ford AB, Moskowitz RW, et al. Studies of illness in the aged. The index of ADL: a standardized measure of biological and psychosocial function. JAMA 1963; 185:914-9.
52. Leake JL. An index of chewing ability. J Public Health Dent 1990; 50:262-7.
53. Levenstein S, Prantera C, Varvo V, et al. Development of the Perceived Stress Questionnaire: a new tool for psychosomatic research. J Psychosom Res 1993; 37:19-32.
54. Bergdahl M, Bergdahl J. Low unstimulated salivary flow and subjective oral dryness: association with medication, anxiety, depression, and stress. J Dent Res 2000; 79:1652-8.
55. Ship JA, Fischer DJ. Metabolic indicators of hydration status in the prediction of parotid salivary-gland function. Arch Oral Biol 1999; 44:343-50.
56. Morita T, Tei Y, Tsunoda J, Inoue S, Chihara S. Determinants of the sensation of thirst in terminally ill cancer patients. Support Care Cancer 2001; 9:177-86.
57. Percival RS, Challacombe SJ, Marsh PD. Flow rates of resting whole and stimulated parotid saliva in relation to age and sex. J Dent Res 1994; 73:1416-20.
58. Miletic ID, Schiffman SS, Miletic VD, Sattely-Miller EA. Salivary IgA secretion rate in young and elderly persons. Physiol Behav 1996; 60:243-8.
59. Tanida T, Ueta E, Tobiume A, Hamada T, Rao F, Osaki T. Influence of aging on candidal growth and adhesion regulatory agents in saliva. J Oral Pathol Med 2001; 30:328-35.
60. Lawrence HP. Salivary markers of systemic disease: noninvasive diagnosis of disease and monitoring of general health. J Can Dent Assoc 2002; 68:170-4.