Localized unresectable non-rhabdo soft tissue sarcomas of the extremities in pediatric age: Results from the Italian studies

Cancer

Volumn 104, Issue 9, 2005, Pages 2006-2012

  Cecchetto, Giovanni ^a   Alaggio, Rita ^a   Dall'Igna, Patrizia ^a   Bisogno, Gianni ^a   Ferrari, Andrea ^b   Gigante, Cosimo ^a   Casanova, Michela ^b   Sotti, Guido ^c   Zanetti, Ilaria ^a   Carli, Modesto ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

^c UNIVERSITY HOSPITAL OF PADOVA   (Italy)

Author keywords

Childhood sarcoma; Extremity soft tissue sarcomas; Nonrhabdo soft tissue sarcoma; Surgery; Tumor grade

Indexed keywords

CYCLOPHOSPHAMIDE; DACTINOMYCIN; DOXORUBICIN; ETOPOSIDE; IFOSFAMIDE; VINCRISTINE;

ADJUVANT CHEMOTHERAPY; ALVEOLAR SOFT PART SARCOMA; ARTICLE; CANCER GRADING; CANCER LOCALIZATION; CHEMOSENSITIVITY; CHILDHOOD CANCER; CLEAR CELL SARCOMA; EPITHELIOID SARCOMA; EWING SARCOMA; FEMALE; FIBROSARCOMA; HEMANGIOPERICYTOMA; HUMAN; ITALY; LEIOMYOSARCOMA; LIPOSARCOMA; MAJOR CLINICAL STUDY; MALE; NERVE SHEATH TUMOR; NEUROECTODERM TUMOR; PERIPHERAL NERVE TUMOR; PRACTICE GUIDELINE; PRIORITY JOURNAL; RELAPSE; RHABDOMYOSARCOMA; SOFT TISSUE SARCOMA; SYNOVIAL SARCOMA; TUMOR VOLUME;

ADOLESCENT; AGE FACTORS; CHEMOTHERAPY, ADJUVANT; CHILD; EXTREMITIES; FEMALE; HUMANS; ITALY; MALE; NEOADJUVANT THERAPY; SARCOMA; SURVIVAL ANALYSIS;

EID: 27244459792     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/cncr.21412     Document Type: Article

References (24)

1. Rao BN, Rodriguez-Calindo C. Local control in childhood extremity sarcomas: salvaging limbs and sparing function. Med Pediatr Oncol. 2003;41:584-587.
2. Rao BN. Nonrhabdomyosarcoma in children: prognostic factors influencing survival. Sem Surg Oncol. 1993;9:524-531.
3. Okcu MF, Munsell M, Treuner J, et al. Synovial sarcoma of childhood and adolescence: a multicenter multivariate analysis and outcome. J Clin Oncol. 2003;21:1602-1612.
4. Spunt SL, Poquette CA, Hurt YS, et al. Prognostic factors for children and adolescents with surgically resected nonrhabdomyosarcoma soft tissue sarcoma: an analysis of 121 patients treated at St. Jude Children's Research Hospital. J Clin Oncol. 1999;17:3697-3705.
5. Hosalkar HS, Dormans JP. Limb sparing surgery for pediatric musculoskeletal tumors. Pediatr Blood Cancer. 2004;42:295-310.
6. Spunt SL, Hill DA, Motosue AM, et al. Clinical features and outcome of initially unresected non metastatic pediatric non-rhabdomyosarcoma soft tissue sarcoma J Clin Oncol. 2002;20:3225-3235.
7. Cecchetto G, Carli M, Alaggio R, et al. Fibrosarcoma in pediatric patients: results of the Italian Cooperative Group studies (1975-1995). J Surg Oncol. 2001;78:225-231.
8. Parham DM, Webber BL Jenkins JJ 3rd, et al. Nonrhabdomyosarcomatous sarcomas of childhood: formulation of simplified system for grading. Mod Pathol. 1995;8:705-710.
9. Carli M, Bisogno G, Mattke A, et al. Malignant peripheral nerve sheath tumors in childhood. A combined experience of the Italian and German Co-operative study Groups. Proceedings of the XXXIII SIOP Meeting. Med Pediatr Oncol. 2001;37:184.
10. Pister PW, Patel SR, Varma DG, et al. Preoperative chemotherapy for Stage IIIB extremity soft tissue sarcoma: long term results from a single institution. J Clin Oncol. 1997;15:3481-3487.
11. Gortzak E, Azzarelli A, Buesa J, et al. A randomized phase II study on neoadjuvant chemotherapy for "high risk" adult soft tissue sarcoma. Eur J Cancer. 2001;37:1096-1103.
12. Meric F, Hess KR, Varma DG, et al. Impact of neoadjuvant therapy on local control of soft tissue sarcoma. [Abstract 2215] Proc Am Soc Clin Oncol. 2000;19:558a.
13. DeLancy TF, Spiro IJ, Suit HD. Neoadjuvant chemotherapy and radiotherapy for large extremity soft-tissue sarcomas. Int J Radiat Oncol Biol Phys. 2003;6:915-916.
14. Carli M, Cecchetto G, Sotti G, Alaggio R, Stevens MCG. Soft tissue sarcomas. In: Pinkerton R, Plowman PN, Pieters R, editors. Paediatric oncology, 3rd ed. London: Arnold, 2004: 339-370.
15. Lejeune FJ, Pujol N, Lienard D, et al. Limb salvage by neoadjuvant isolated perfusion with TNFa and melphalan for non resectable soft tissue sarcoma of the extremities. Eur J Surg Oncol. 2000;26:669-678.
16. Hohenberger P, Tunn PU. Isolated limb perfusion with rhTNF-alpha and melphalan for locally recurrent childhood synovial sarcoma of the limb. J Pediatr Hematol Oncol. 2003;25:905-909.
17. Cecchetto G, Guglielmi M, Bisogno G, et al. Localized soft tissue sarcomas of extremities: the experience of the Italian studies. Proceedings of the XXXIV IPSO Meeting. Med Pediatr Oncol. 2002;39:220.
18. Blakely ML, Spurbeck WW, Pappo AS, et al. The impact of margin of resection on outcome in pediatric nonrhabdomyosarcoma soft tissue sarcoma. J Pediatr Surg. 1999;34:672-675.
19. Antoniello L, Cecchetto G, Carli M, et al. Role of mutilating surgery in the treatment of non-chemosensitive pediatric soft tissue sarcomas. Experience of the Italian Cooperative Group Studies RMS-79 and RMS-88. Pediatr Med Chir. 2003;25:255-260.
20. Hayes-Jordan AA, Spunt SL, Poquette CA, et al. Nonrhabdomyosarcoma soft tissue sarcomas in children: is age at diagnosis an important variable? J Pediatr Surg. 2000;35:948-954.
21. Ariel IM. Incidence of metastases to lymph nodes from soft tissue sarcomas. Semin Surg Oncol. 1988;4:27-29.
22. Van Glabble M, Van Oosterom AT, Oosteruis JW, et al. Prognostic factors for the outcome of chemotherapy in advanced soft tissue sarcoma. An analysis of 2,185 patients treated with antracycline containing first line regimen - A European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Study. J Clin Oncol. 1999;17:150-157.
23. Pisters PW, Leung DH, Woodruff J, et al. Analysis of prognostic factors in 1,041 patients with localized soft tissue sarcomas of the extremities. J Clin Oncol. 1996;14:1679-1689.
24. Pratt CB, Maurer HM, Gieser P, et al. Treatment of unresectable or metastatic pediatric soft tissue sarcomas with surgery, irradiation and chemotherapy: a Pediatric Oncology Group Study. Med Pediatr Oncol. 1998;30:201-209.