Prognostic factors for the outcome of chemotherapy in advanced soft tissue sarcoma: An analysis of 2,185 patients treated with anthracycline- containing first-line regimens - A European organization for research and treatment of cancer soft tissue and bone sarcoma group study

Journal of Clinical Oncology

Volumn 17, Issue 1, 1999, Pages 150-157

  Van Glabbeke, Martine ^a   Van Oosterom, A T ^a   Oosterhuis, J W ^a   Mouridsen, H ^a   Crowther, D ^a   Somers, R ^a   Verweij, J ^a   Santoro, A ^a   Buesa, J ^a   Tursz, T ^a  

^a EORTC DATA CENTER   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; CYCLOPHOSPHAMIDE; DACARBAZINE; DOXORUBICIN; EPIRUBICIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IFOSFAMIDE; VINCRISTINE;

ADULT; ADVANCED CANCER; ARTICLE; DOSE RESPONSE; HUMAN; LIVER METASTASIS; MAJOR CLINICAL STUDY; OSTEOSARCOMA; PRIORITY JOURNAL; PROGNOSIS; SOFT TISSUE SARCOMA; TREATMENT OUTCOME;

EID: 0032952928     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/jco.1999.17.1.150     Document Type: Article

References (33)

1. Pinedo H, Bramwell VHC, Mouridsen HT, et al: CYVADIC in advanced soft tissue sarcoma: A randomized study comparing two schedules. Cancer 53:1825-1832, 1984
2. Mouridsen HT, Batshold L, Somers R, et al: Adriamycin versus epirubicin in advanced soft tissue sarcoma: A randomized phase II/phase III study of the EORTC Soft Tissue and Bone Sarcoma Group. Eur J Cancer Clin Oncol 23:1477-1483, 1987
3. Schütte J, Mouridsen HT, Stewart W, et al: For the EORTC Soft Tissue and Bone Sarcoma Group: Ifosfamide plus doxorubicin in previously untreated patients with advanced soft tissue sarcoma. Eur J Cancer 26:558-561, 1990
4. Santoro A, Tursz T, Mouridsen H, et al: Doxorubicin versus CYVADIC versus doxorubicin plus ifosfamide in first-line treatment of advanced soft tissue sarcomas: A randomized study of the EORTC Soft Tissue and Bone Sarcoma Group. J Clin Oncol 13:1537-1545, 1995
5. Dombernowsky P, Mouridsen H, Nielsen OS, et al: A phase III study comparing adriamycin vs. two schedules of high dose epirubicin in advanced soft tissue sarcoma. Proc Am Soc Clin Oncol 14:237, 1995 (abstr 1688)
6. Steward WP, Verweij J, Somers R, et al: Granulocyte-macrophage colony-stimulating factor (GM-CSF) allows safe escalation of dose intensity of chemotherapy in metastatic adult soft tissue sarcoma: A study of the European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group. J Clin Oncol 11:15-21, 1993
7. Tursz T, Verweij J, Judson I, et al: Is high-dose chemotherapy of interest in advanced soft tissue sarcomas (ASTS)? An EORTC randomized phase III trial. Proc Am Soc Clin Oncol 15:337, 1996 (abstr 973)
8. World Health Organization: WHO Handbook for Reporting Results of Cancer Treatment. Geneva, Switzerland, WHO, WHO Offset Publication 48, 1979
9. Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481, 1958
10. Mantel L: Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother Rep 50:163-170, 1966
11. Sylvester R: On the analysis of response rates in studies of advanced disease. Eur J Cancer Suppl 1:5-7, 1980
12. Cox DR: Regression models and life tables. [with discussion]. J R Stat Soc B 34:187-220, 1972
13. Cox DR: The Analysis of Binary Data. London, United Kingdom, Methuen, 1970
14. van Unnik JAM, Coindre JM, Contesso C, et al: Grading of soft tissue sarcomas: Experience of the EORTC Soft Tissue and Bone Sarcoma Group. Eur J Cancer 29A:2089-2093, 1993
15. Peabody TD, Monson D, Montag A, et al: A comparison of the prognoses for deep and subcutaneous sarcomas of the extremities. J Bone Joint Surg Am 76:1167-1173, 1994
16. Gustafson P: Soft tissue sarcoma: Epidemiology and prognosis in 508 patients. Acta Orthop Scand Suppl 259:1-31, 1994
17. Tomita Y, Kuratsu S, Naka N, et al: A staging system for soft-tissue sarcoma and its evaluation in relation to treatment. Int J Cancer 58:168-173, 1994
18. Singer S, Corson JM, Gonin R, et al: Prognostic factors predictive of survival and local recurrence for extremity soft tissue sarcoma. Ann Surg 219:165-173, 1994
19. LeVay J, O'Sullivan B, Catton C, et al: Outcome and prognostic factors in soft tissue sarcoma in the adult. Int J Radiat Oncol Biol Phys 27:1091-1099, 1993
20. Gaynor JJ, Tan CC, Casper ES, et al: Refinement of clinicopathologic staging for localized soft tissue sarcoma of the extremity: A study of 423 adults. J Clin Oncol 10:1317-1329, 1992
21. Saddegh MK, Lindholm J, Lundberg A, et al: Staging of soft-tissue sarcomas: Prognostic analysis of clinical and pathological features. J Bone Joint Surg Br 74:495-500, 1992
22. Baldursson G, Agnarsson BA, Benediktsdottir KR, et al: Soft tissue sarcomas in Iceland 1955-1988: Analysis of survival and prognostic factors. Acta Oncol 30:563-568, 1991
23. Choong PF, Gustafson P, Willen H, et al: Prognosis following locally recurrent soft-tissue sarcoma: A staging system based on primary and recurrent tumour characteristics. Int J Cancer 60:33-37, 1995
24. Bauer HC, Kreicbergs A, Tribukait B: DNA content prognostic in soft tissue sarcoma: 102 patients followed for 1-10 years. Acta Orthop Scand 62:187-194, 1991
25. Jensen OM, Hogh J, Ostgaard SE, et al: Histopathological grading of soft tissue tumours: Prognostic significance in a prospective study of 278 consecutive cases. J Pathol 163:19-24, 1991
26. Coindre Jean-Michel, Terrier Philippe, Binh Bui Nguyen, et al: Prognostic factors in adult patients with locally controlled soft tissue sarcoma: A study of 546 patients from the French Federation of Cancer Centers Sarcoma Group. J Clin Oncol 14:869-877, 1996
27. van Geel AN, van Coevorden F, Blankensteijn JD, et al: Surgical treatment of pulmonary metastases from soft tissue sarcomas: A retrospective study in the Netherlands. J Surg Oncol 56:172-177, 1994
28. Girard P, Baldeyrou P, Le Chevalier T, et al: Surgical resection of pulmonary metastases: Up to what number? Am J Respir Crit Care Med 149:469-476, 1994
29. Ueda T, Uchida A, Kodama K, et al: Aggressive pulmonary metastasectomy for soft tissue sarcomas. Cancer 72:1919-1925, 1993 (see comments)
30. Verazin GT, Warneke JA, Driscoll DL, et al: Resection of lung metastases from soft-tissue sarcomas: A multivariate analysis. Arch Surg 127:1407-1411, 1992
31. Borden EC, Amato DA, Rosenbaum CH, et al: Randomized comparison of three adriamycin regiments for metastastic soft tissue sarcomas. J Clin Oncol 5:840-850, 1987
32. Omura GA, Major FJ, Blessing JA, et al: A randomized study of adriamycin with and without dimethyl triazenoimidazole carboxamide in advanced uterine sarcomas. Cancer 52:626-632, 1983
33. Yap BS, Baker LH, Sinkovics JG, et al: Cyclophosphamide, vincristine, adriamycin and DTIC (CYVADIC) combination chemotherapy for the treatment of advanced sarcomas. Cancer Treat Rep 64:93-98, 1980