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Volumn 6, Issue 4, 2005, Pages 325-333

Gastrointestinal bleeding associated with concurrent capecitabine and radiotherapy in patients with pancreatic cancer

Author keywords

Deoxycytidine; Dihydrouracil dehydrogenase (NADP); Drug toxicity; Fluorouracil; Gastrointestinal hemorrhage; Pancreatic neoplasms; Radiotherapy; Thymidine pPhosphorylase

Indexed keywords

CAPECITABINE; ANTINEOPLASTIC ANTIMETABOLITE; DEOXYCYTIDINE; DRUG DERIVATIVE; PRODRUG;

EID: 27244454508     PISSN: 15908577     EISSN: 15908577     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (3)

References (28)
  • 1
    • 0038387494 scopus 로고    scopus 로고
    • 5-fluorouracil: Mechanisms of action and clinical strategies
    • Longley DB, Harkin DP, Johnston PG. 5-fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer 2003; 3:330-8.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 330-338
    • Longley, D.B.1    Harkin, D.P.2    Johnston, P.G.3
  • 2
    • 0033666364 scopus 로고    scopus 로고
    • Oral fluoropyrimidines in cancer treatment
    • Lewis NL, Meropol NJ. Oral fluoropyrimidines in cancer treatment. Cancer Invest 2000; 18:747-60.
    • (2000) Cancer Invest. , vol.18 , pp. 747-760
    • Lewis, N.L.1    Meropol, N.J.2
  • 3
    • 0032127244 scopus 로고    scopus 로고
    • Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluoruracil selectively in tumours by enzymes concentrated in human liver and cancer tissue
    • Miwa M, Ura M, Nishida M, Sawada N, Ishikawa T, Mori K, et al. Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluoruracil selectively in tumours by enzymes concentrated in human liver and cancer tissue. Eur J Cancer 1998; 34:1274-81.
    • (1998) Eur. J. Cancer , vol.34 , pp. 1274-1281
    • Miwa, M.1    Ura, M.2    Nishida, M.3    Sawada, N.4    Ishikawa, T.5    Mori, K.6
  • 4
    • 0344541873 scopus 로고    scopus 로고
    • Tumor selective delivery of 5-fluorouracil by capecitabine, a new oral fluoropyrimidine carbamate, in human cancer xenografts
    • Ishikawa T, Utoh M, Sawada N, Nishida M, Fukase Y, Sekiguchi F, Ishitsuka H. Tumor selective delivery of 5-fluorouracil by capecitabine, a new oral fluoropyrimidine carbamate, in human cancer xenografts. Biochem Pharmacol 1998; 55:1091-7.
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 1091-1097
    • Ishikawa, T.1    Utoh, M.2    Sawada, N.3    Nishida, M.4    Fukase, Y.5    Sekiguchi, F.6    Ishitsuka, H.7
  • 5
    • 0034016415 scopus 로고    scopus 로고
    • Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients
    • Schuller J, Cassidy J, Dumont E, Roos B, Durston S, Banken L, et al. Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients. Cancer Chemother Pharmacol 2000; 45:291-7.
    • (2000) Cancer Chemother. Pharmacol. , vol.45 , pp. 291-297
    • Schuller, J.1    Cassidy, J.2    Dumont, E.3    Roos, B.4    Durston, S.5    Banken, L.6
  • 6
    • 0034694856 scopus 로고    scopus 로고
    • World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects
    • World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA 2000; 284:3043-5.
    • (2000) JAMA , vol.284 , pp. 3043-3045
  • 9
    • 0002548405 scopus 로고    scopus 로고
    • 5-Fluoropyrimidines
    • Chabner BA, Longo DL, eds. 2nd Ed. Philadelphia, PA, USA: Lippencott
    • Grem JL. 5-Fluoropyrimidines In: Chabner BA, Longo DL, eds. Cancer Chemotherapy and Biotherapy:Principles and Practice. 2nd Ed. Philadelphia, PA, USA: Lippencott, 1996:149-211.
    • (1996) Cancer Chemotherapy and Biotherapy: Principles and Practice , pp. 149-211
    • Grem, J.L.1
  • 10
    • 0027482012 scopus 로고
    • Resistance to fluorodeoxyuridine - Induced DNA damage and cytotoxicity correlates with an elevation of deoxyuridine triphosphatase activity and failure to accumulate deoxyuridine triphosphate
    • Canman CE, Lawrence TS, Shewach DS, Tang HY, Maybaum J. Resistance to fluorodeoxyuridine - induced DNA damage and cytotoxicity correlates with an elevation of deoxyuridine triphosphatase activity and failure to accumulate deoxyuridine triphosphate. Cancer Res 1993; 53:5219-24.
    • (1993) Cancer Res. , vol.53 , pp. 5219-5224
    • Canman, C.E.1    Lawrence, T.S.2    Shewach, D.S.3    Tang, H.Y.4    Maybaum, J.5
  • 11
    • 0024532021 scopus 로고
    • Interaction of deoxyuridine with fluorouracil and dipyridamole in human colon cancer cell line
    • Grem JL, Mulcahy RT, Miller EM, Allegra CJ, Fischer PH. Interaction of deoxyuridine with fluorouracil and dipyridamole in human colon cancer cell line. Biochem Pharmacol 1989; 38:51-9.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 51-59
    • Grem, J.L.1    Mulcahy, R.T.2    Miller, E.M.3    Allegra, C.J.4    Fischer, P.H.5
  • 12
    • 0028982818 scopus 로고
    • Ratio of 2′-deozyadenosine-5′-triphosphate /thymidine-5′-triphosphate influences the commitment of human colon carcinoma cells to thymidineless death
    • Houghton JA, Tillman DM, Harwood FG. Ratio of 2′-deozyadenosine-5′-triphosphate /thymidine-5′-triphosphate influences the commitment of human colon carcinoma cells to thymidineless death. Clin Cancer Res 1995; 1:723-30.
    • (1995) Clin. Cancer Res. , vol.1 , pp. 723-730
    • Houghton, J.A.1    Tillman, D.M.2    Harwood, F.G.3
  • 13
    • 0028051772 scopus 로고
    • The effect of 5-fluoropyrimidines on nascent DNA synthesis in Chinese hamster ovary cells monitored by pH-step alkaline and neutral elution
    • Jones S, Willmore E, Durkacz BW. The effect of 5-fluoropyrimidines on nascent DNA synthesis in Chinese hamster ovary cells monitored by pH-step alkaline and neutral elution. Carcinogenesis 1994; 15:2435.
    • (1994) Carcinogenesis , vol.15 , pp. 2435
    • Jones, S.1    Willmore, E.2    Durkacz, B.W.3
  • 14
    • 0032695102 scopus 로고    scopus 로고
    • X-ray irradiation induces thymidine phosphorylase and enhances the efficacy of capecitabine (Xeloda) in human cancer xenografts
    • Sawada N, Ishikawa T, Sekiguchi F, Tanaka Y, Ishitsuka H. X-ray irradiation induces thymidine phosphorylase and enhances the efficacy of capecitabine (Xeloda) in human cancer xenografts. Clin Cancer Res 1999; 5:2948-53.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 2948-2953
    • Sawada, N.1    Ishikawa, T.2    Sekiguchi, F.3    Tanaka, Y.4    Ishitsuka, H.5
  • 16
    • 18744370994 scopus 로고    scopus 로고
    • RhuMab VEGF (bevacizumab) with concurrent radiotherapy and capecitabine in locally advanced pancreatic cancer: An active, well tolerated regimen
    • Crane CH, EllisLM, Oreilly M, Ho L, Abbruzzese JL, Evans DB, et al. RhuMab VEGF (bevacizumab) with concurrent radiotherapy and capecitabine in locally advanced pancreatic cancer: An active, well tolerated regimen. Int J Radial Oncol Biol Phys 2004; 60(Suppl 1):S149.
    • (2004) Int. J. Radiat. Oncol. Biol. Phys. , vol.60 , Issue.SUPPL. 1
    • Crane, C.H.1    Ellis, L.M.2    Oreilly, M.3    Ho, L.4    Abbruzzese, J.L.5    Evans, D.B.6
  • 17
    • 0037208590 scopus 로고    scopus 로고
    • Combining capecitabine and gemcitabine in patients with advanced pancreatic carcinoma: A phase i/ii trial
    • Hess V, Salzberg M, Borner M, Morant R, Roth AD, Ludwig C, Herrmann R. Combining capecitabine and gemcitabine in patients with advanced pancreatic carcinoma: a phase i/ii trial. J Clin Oncol 2003; 21:66-8.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 66-68
    • Hess, V.1    Salzberg, M.2    Borner, M.3    Morant, R.4    Roth, A.D.5    Ludwig, C.6    Herrmann, R.7
  • 19
    • 0001282261 scopus 로고    scopus 로고
    • Capecitabine combined with simultaneous radiotherapy in rectal cancer: A phase I study
    • (Abstr.)
    • Reese T, Tanner J, Frings S, Dunst J. Capecitabine combined with simultaneous radiotherapy in rectal cancer: A phase I study (Abstr.). Int J Radiat Oncol Biol Phys 2000; 48:120-1.
    • (2000) Int. J. Radiat. Oncol. Biol. Phys. , vol.48 , pp. 120-121
    • Reese, T.1    Tanner, J.2    Frings, S.3    Dunst, J.4
  • 20
    • 0003326684 scopus 로고    scopus 로고
    • A phase I study of capecitabine combined with radiotherapy locally advanced potentially operable rectal cancer
    • 104a (Abstract)
    • Ngan S, Zalcberg J, Kell A, Michael M, MacKay J, Lim Joon, et al. A phase I study of capecitabine combined with radiotherapy locally advanced potentially operable rectal cancer (Abstract). Proc ASCO 2001; 20:591, 104a.
    • (2001) Proc. ASCO , vol.20 , pp. 591
    • Ngan, S.1    Zalcberg, J.2    Kell, A.3    Michael, M.4    MacKay, J.5    Joon, L.6
  • 21
    • 4243958383 scopus 로고    scopus 로고
    • Enhanced tumoricidal effect of preoperative chemoradiation using capecitabine for locally advanced rectal cancer
    • 104b (Abstract)
    • Yoon WH, Choi JH, Kim JR, Kim T, Lim K, Hwang B, et al. Enhanced tumoricidal effect of preoperative chemoradiation using capecitabine for locally advanced rectal cancer (Abstract). Proc ASCO 2001; 20:2165, 104b.
    • (2001) Proc. ASCO , vol.20 , pp. 2165
    • Yoon, W.H.1    Choi, J.H.2    Kim, J.R.3    Kim, T.4    Lim, K.5    Hwang, B.6
  • 22
    • 0036644860 scopus 로고    scopus 로고
    • Treatment side effects. Case 1. Radiation recall phenomenon after administration of capecitabine
    • Ortmann E, Hohenberg G. Treatment side effects. Case 1. Radiation recall phenomenon after administration of capecitabine. J Clin Oncol 2002; 20:3029-30.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 3029-3030
    • Ortmann, E.1    Hohenberg, G.2
  • 24
    • 0030938059 scopus 로고    scopus 로고
    • Protracted 5-fluorouracil infusion with concurrent radiotherapy as a treatment for locally advanced pancreatic carcinoma
    • Ishii H, Okada S, Tokuuye K, Nose H, Okusaka T, Yoshimori M, et al. Protracted 5-fluorouracil infusion with concurrent radiotherapy as a treatment for locally advanced pancreatic carcinoma. Cancer 1997; 79:1516-20.
    • (1997) Cancer , vol.79 , pp. 1516-1520
    • Ishii, H.1    Okada, S.2    Tokuuye, K.3    Nose, H.4    Okusaka, T.5    Yoshimori, M.6
  • 25
    • 0030949966 scopus 로고    scopus 로고
    • Multisite mucous membrane bleeding due to a possible interaction between warfarin and 5-fluorouracil
    • Brown MC. Multisite mucous membrane bleeding due to a possible interaction between warfarin and 5-fluorouracil. Pharmacotherapy 1997; 17:631-633.
    • (1997) Pharmacotherapy , vol.17 , pp. 631-633
    • Brown, M.C.1
  • 26
    • 4344626528 scopus 로고    scopus 로고
    • Phase II study of radiotherapy combined with gemcitabine for locally advanced pancreatic cancer
    • Okusaka T, Ito Y, Ueno H, Ikeda M, Takezako Y, Morizane C, et al. Phase II study of radiotherapy combined with gemcitabine for locally advanced pancreatic cancer. Br J Cancer 2004; 91:673-7.
    • (2004) Br. J. Cancer , vol.91 , pp. 673-677
    • Okusaka, T.1    Ito, Y.2    Ueno, H.3    Ikeda, M.4    Takezako, Y.5    Morizane, C.6
  • 27
  • 28
    • 0034306137 scopus 로고    scopus 로고
    • Eastern cooperative oncology group phase i trial of protracted venous infusion fluorouracil plus weekly gemcitabine with concurrent radiation therapy in patients with locally advanced pancreas cancer: A regimen with unexpected early toxicity
    • Talamonti MS, Catalano PJ, Vaughn DJ, Whittington R, Beauchamp RD, Berlin J, Benson AB 3rd. Eastern cooperative oncology group phase i trial of protracted venous infusion fluorouracil plus weekly gemcitabine with concurrent radiation therapy in patients with locally advanced pancreas cancer: a regimen with unexpected early toxicity. J Clin Oncol 2000; 18:3384-9.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 3384-3389
    • Talamonti, M.S.1    Catalano, P.J.2    Vaughn, D.J.3    Whittington, R.4    Beauchamp, R.D.5    Berlin, J.6    Benson III, A.B.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.