Chronic lymphocytic leukaemia: A review of the immuno-architecture

Current Topics in Microbiology and Immunology

Volumn 294, Issue , 2005, Pages 91-107

  Rosati, S ^a   Kluin, M ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD23 ANTIGEN; CYCLIN D1; CYTOKINE; INHIBITOR OF APOPTOSIS PROTEIN; INTERFERON REGULATORY FACTOR 4; PROTEIN KINASE ZAP 70; PROTEIN TYROSINE KINASE; SURVIVIN; T LYMPHOCYTE RECEPTOR;

ANTIGEN EXPRESSION; APOPTOSIS; B LYMPHOCYTE; CELL INTERACTION; CELL PROLIFERATION; CHRONIC LYMPHATIC LEUKEMIA; ENZYME ANALYSIS; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; IMMUNOPHENOTYPING; IMMUNOREACTIVITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

EID: 27144520904     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/3-540-29933-5_6     Document Type: Review

References (56)

1. Admirand JH, Rassidakis GZ, Abruzzo LV, Valbuena JR, Jones D, Jeffrey Medeiros L (2004) Immunohistochemical detection of ZAP-70 in 341 cases of non-Hodgkin and Hodgkin lymphoma. Mod Pathol 17:954-961
2. Ambrosini G, Adida C, Altieri DC (1997) A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 3:917-921
3. Avet-Loiseau H, Garand R, Gaillard F, Daviet A, Mellerin MP, Robillard N, Bouyge I, Arcot S, Batzer M, Talmant P, Harousseau JL, Milpied N, Bataille R (1998) Detection of t(11;14) using interphase molecular cytogenetics in mantle cell lymphoma and atypical chronic lymphocytic leukemia. Genes Chromosomes Cancer 23:175-182
4. Blume-Jensen P, Hunter T (2001) Oncogenic kinase signalling. Nature 17;411:355-365
5. Bonnefoy JY, Lecoanet-Henchoz S, Aubry JP, Gauchat JF, Graber P (1995) CD23 and B-cell activation. Curr Opin Immunol 7:355-359
6. Calame KL, Lin KI, Tunyaplin C (2003) Regulatory mechanisms that determine the development and function of plasma cells. Annu Rev Immunol 21:205-30 [review]
7. Caligaris-Cappio F (2003) Role of the microenvironment in chronic lymphocytic leukaemia. Br J Haematol 123:380-388
8. Caligaris-Cappio F, Hamblin TJ (1999) B-cell chronic lymphocytic leukemia: a bird of a different feather. J Clin Oncol 17:399-408
9. Chang CC, Lorek J, Sabath DE, Li Y, Chitambar CR, Logan B, Kampalath B, Cleveland RP (2002) Expression of MUM1/IRF4 correlates with clinical outcome in patients with B-cell chronic lymphocytic leukemia. Blood 100:4671-4675
10. Chen L, Widhopf G, Huynh L, Rassenti L, Rai KR, Weiss A, Kipps TJ (2002) Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia. Blood 100:4609-4614
11. Cheuk W, Wong KO, Wong CS, Chan JK (2004) Consistent immunostaining for cyclin D1 can be achieved on a routine basis using a newly available rabbit monoclonal antibody. Am J Surg Pathol 28:801-807
12. Chilosi M, Pizzolo G, Caligaris-Cappio F, Ambrosetti A, Vinante F, Morittu L, Bonetti F, Fiore-Donati L, Janossy G (1985) Immunohistochemical demonstration of follicular dendritic cells in bone marrow involvement of B-cell chronic lymphocytic leukemia. Cancer 56:328-332
13. Crespo M, Bosch F, Villamor N, Bellosillo B, Colomer D, Rozman M, Marce S, Lopez-Guillermo A, Campo E, Montserrat E (2003) ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia. N Engl J Med 348:1764-1775
14. Delespesse G, Suter U, Mossalayi D, Bettler B, Sarfati M, Hofstetter H, Kilcherr E, Debre P, Dalloul A (1991) Expression, structure, and function of the CD23 antigen. Adv Immunol 49:149-191
15. Dugas B, Mossalayi MD, Damais C, Kolb JP (1995) Nitric oxide production by human monocytes: evidence for a role of CD23. Immunol Today 16:574-580
16. Eisenbeis CF, Singh H, Storb U (1995) Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator. Genes Dev 9:1377-1387
17. Ewart MA, Ozanne BW, Cushley W (2002) The CD23a and CD23b proximal promoters display different sensitivities to exogenous stimuli in B lymphocytes. Genes Immun 3:158-164
18. Falini B, Fizzotti M, Pucciarini A, Bigerna B, Marafioti T, Gambacorta M, Pacini R, Alunni C, Natali-Tanci L, Ugolini B, Sebastiani C, Cattoretti G, Pileri S, Dalla-Favera R, Stein H (2000) A monoclonal antibody (MUM1p) detects expression of the MUM1/IRF4 protein in a subset of germinal center B cells, plasma cells, and activated T cells. Blood 95:2084-2092
19. Fournier S, Yang LP, Delespesse G, Rubio M, Biron G, Sarfati M (1995) The two CD23 isoforms display differential regulation in chronic lymphocytic leukaemia. Br J Haematol 89:373-379
20. Ghia P, Strola G, Granziero L, Geuna M, Guida G, Sallusto F, Ruffing N, Montagna L, Piccoli P, Chilosi M, Caligaris-Cappio F (2002) Chronic lymphocytic leukemia B cells are endowed with the capacity to attract CD4+, CD40L+ T cells by producing CCL22. Eur J Immunol 32:1403-1413
21. Goller ME, Kneitz C, Mehringer C, Muller K, Jelley-Gibbs DM, Gosselin EJ, Wilhelm M, Tony HP (2002) Regulation of CD23 isoforms on B-chronic lymphocytic leukemia. Leuk Res 26:795-802
22. Granziero L, Ghia P, Circosta P, Gottardi D, Strola G, Geuna M, Montagna L, Piccoli P, Chilosi M, Caligaris-Cappio F (2001) Survivin is expressed on CD40 stimulation and interfaces proliferation and apoptosis in B-cell chronic lymphocytic leukemia. Blood 97:2777-2783
23. Grossman A, Mittrucker HW, Nicholl J, Suzuki A, Chung S, Antonio L, Suggs S, Sutherland GR, Siderovski DP, Mak TW (1996) Cloning of human lymphocyte-specific interferon regulatory factor (hLSIRF/hIRF4) and mapping of the gene to 6p23-p25. Genomics 37:229-233
24. Gupta S, Jiang M, Anthony A, Pernis AB (1999) Lineage-specific modulation of interleukin 4 signaling by interferon regulatory factor 4. J Exp Med 190:1837-1848
25. Gupta S, Anthony A, Pernis AB (2001) Stage-specific modulation of IFN-regulatory factor 4 function by Kruppel-type zinc finger proteins. J Immunol 166:6104-6111
26. Haralambieva E, Jones M, Roncador GM, Cerroni L, Lamant L, Ott G, Rosenwald A, Sherman C, Thorner P, Kusec R, Wood KM, Campo E, Falini B, Ramsay A, Marafioti T, Stein H, Kluin PM, Pulford K, Mason DY (2002) Tyrosine phosphorylation in human lymphomas. Histochem J 34:545-552
27. Hubmann R, Schwarzmeier JD, Shehata M, Hilgarth M, Duechler M, Dettke M, Berger R (2002) Notch2 is involved in the overexpression of CD23 in B-cell chronic lymphocytic leukemia. Blood 99:3742-3747
28. Iida S, Rao PH, Butler M, Corradini P, Boccadoro M, Klein B, Chaganti RS, Dalla-Favera R (1997) Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma. Nat Genet 17:226-230
29. Ito M, Iida S, Inagaki H, Tsuboi K, Komatsu H, Yamaguchi M, Nakamura N, Suzuki R, Seto M, Nakamura S, Morishima Y, Ueda R (2002) MUM1/IRF4 expression is an unfavorable prognostic factor in B-cell chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL). Jpn J Cancer Res 93:685-694
30. Kay NE, Pittner BT (2003) IL-4 biology: impact on normal and leukemic CLL B cells. Leuk Lymphoma 44:897-903
31. Kitada S, Zapata JM, Andreeff M, Reed JC (1999) Bryostatin and CD40-ligand enhance apoptosis resistance and induce expression of cell survival genes in B-cell chronic lymphocytic leukaemia. Br J Haematol 106:995-1004
32. Kneitz C, Goller M, Tony H, Simon A, Stibbe C, Konig T, Serfling E, Avots A (2002) The CD23b promoter is a target for NF-AT transcription factors in B-CLL cells. Biochim Biophys Acta 1588:41-47
33. Kolb JP, Abadie A, Proschnicka-Chalufour A, de Gramont A, Poggioli J (1994) CD23-mediated cell signalling. J Lipid Mediat Cell Signal 9:27-35
34. Kolb JP, Roman V, Mentz F, Zhao H, Rouillard D, Dugas N, Dugas B, Sigaux F (2001) Contribution of nitric oxide to the apoptotic process in human B cell chronic lymphocytic leukaemia. Leuk Lymphoma 40:243-257
35. Lampert IA, Wotherspoon A, Van Noorden S, Hasserjian RP (1999) High expression of CD23 in the proliferation centers of chronic lymphocytic leukemia in lymph nodes and spleen. Hum Pathol 30:648-654
36. Lanham S, Hamblin T, Oscier D, Ibbotson R, Stevenson F, Packham G (2003) Differential signaling via surface IgM is associated with VH gene mutational status and CD38 expression in chronic lymphocytic leukaemia. Blood 101:1087-1093
37. Li F, Ambrosini G, Chu EY, Plescia J, Tognin S, Marchisio PC, Altieri DC (1998) Control of apoptosis and mitotic spindle checkpoint by survivin. Nature 396:580-584
38. Marecki S, Fenton MJ (2002) The role of IRF-4 in transcriptional regulation. J Interferon Cytokine Res 22:121-33 [review]
39. Matutes E, Carrara P, Coignet L, Brito-Babapulle V, Villamor N, Wotherspoon A, Catovsky D (1999) FISH analysis for BCL-1I rearrangements and trisomy 12 helps the diagnosis of atypical B cell leukaemias. Leukemia 13:1721-1726
40. Meade J, Tybulewicz VL, Turner M (2004) The tyrosine kinase Syk is required for light chain isotype exclusion but dispensable for the negative selection of B cells. Eur J Immunol 34:1102-1110
41. Mittrucker HW, Matsuyama T, Grossman A, Kundig TM, Potter J, Shahinian A, Wakeham A, Patterson B, Ohashi PS, Mak TW (1997) Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function. Science 275:540-543
42. Orchard JA, Ibbotson RE, Davis Z, Wiestner A, Rosenwald A, Thomas PW, Hamblin TJ, Staudt LM, Oscier DG (2004) ZAP-70 expression and prognosis in chronic lymphocytic leukaemia. Lancet 363:105-111
43. Pernis AB (2002) The role of IRF-4 in B and T cell activation and differentiation. J Interferon Cytokine Res 22:111-120 [review]
44. Pulford K, Delsol G, Roncador G, Biddolph S, Jones M, Mason DY (1999) Immunohistochemical screening for oncogenic tyrosine kinase activation. J Pathol 187:588-593
45. Rassenti LZ, Huynh L, Toy TL, Chen L, Keating MJ, Gribben JG, Neuberg DS, Flinn IW, Rai KR, Byrd JC, Kay NE, Greaves A, Weiss A, Kipps TJ (2004) ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia. N Engl J Med 351:893-901
46. Rosenwald A, Alizadeh AA, Widhopf G, Simon R, Davis RE, Yu X, Yang L, Pickeral OK, Rassenti LZ, Powell J, Botstein D, Byrd JC, Grever MR, Cheson BD, Chiorazzi N, Wilson WH, Kipps TJ, Brown PO, Staudt LM (2001) Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia. J Exp Med 194:1639-1647
47. Ruchlemer R, Parry-Jones N, Brito-Babapulle V, Attolico I, Wotherspoon AC, Matutes E, Catovsky D (2004) B-prolymphocytic leukaemia with t(11;14) revisited: a splenomegalic form of mantle cell lymphoma evolving with leukaemia. Br J Haematol 125:330-336
48. Sawyers CL, McLaughlin J, Goga A, Havlik M, Witte O (1994) The nuclear tyrosine kinase c-Abl negatively regulates cell growth. Cell 77:121-131
49. Scheijen B, Griffin JD (2002) Tyrosine kinase oncogenes in normal hematopoiesis and hematological disease. Oncogene 21:3314-3333
50. Schweighoffer E, Vanes L, Mathiot A, Nakamura T, Tybulewicz VL (2003) Unexpected requirement for ZAP-70 in pre-B cell development and allelic exclusion. Immunity 18:523-533
51. Sloan-Lancaster J, Zhang W, Presley J, Williams BL, Abraham RT, Lippincott-Schwartz J, Samelson LE (1997) Regulation of ZAP-70 intracellular localization: visualization with the green fluorescent protein. J Exp Med 186:1713-1724
52. Stevenson FK, Caligaris-Cappio F (2004) Chronic lymphocytic leukemia: revelations from the B-cell receptor. Blood 103:4389-4395
53. Visan I, Goller M, Berberich I, Kneitz C, Tony HP (2003) Pax-5 is a key regulator of the B cell-restricted expression of the CD23a isoform. Eur J Immunol 33:1163-1173
54. Wang F, Kikutani H, Tsang SF, Kishimoto T, Kieff E (1991) Epstein-Barr virus nuclear protein 2 transactivates a cis-acting CD23 DNA element. J Virol 65:4101-4106
55. Wiestner A, Rosenwald A, Barry TS, Wright G, Davis RE, Henrickson SE, Zhao H, Ibbotson RE, Orchard JA, Davis Z, Stetler-Stevenson M, Raffeld M, Arthur DC, Marti GE, Wilson WH, Hamblin TJ, Oscier DG, Staudt LM (2003) ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile. Blood 101:4944-4951
56. Yamagata T, Nishida J, Tanaka S, Sakai R, Mitani K, Yoshida M, Taniguchi T, Yazaki Y, Hirai H (1996) A novel interferon regulatory factor family transcription factor, IC-SAT/Pip/LSIRF, that negatively regulates the activity of interferon-regulated genes. Mol Cell Biol 16:1283-1294