메뉴 건너뛰기




Volumn 11, Issue 20, 2005, Pages 7415-7425

Modeling the pharmacodynamics of highly schedule-dependent agents: Exemplified by cytarabine-based regimens in acute myeloid leukemia

Author keywords

[No Author keywords available]

Indexed keywords

CYTARABINE; DAUNORUBICIN; ETOPOSIDE; IDARUBICIN; MAFOSFAMIDE; MITOXANTRONE; TOPOTECAN;

EID: 27144516782     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-05-0360     Document Type: Article
Times cited : (8)

References (55)
  • 1
    • 0345104178 scopus 로고    scopus 로고
    • Double induction strategy for acute myeloid leukemia: The effect of high-dose cytarabine with mitoxantrone instead of standard-dose cytarabine with daunorubicin and 6-thioguanine: A randomized trial by the German AML Cooperative Group
    • Buchner T, Hiddemann W, Wormann B, et al. Double induction strategy for acute myeloid leukemia: the effect of high-dose cytarabine with mitoxantrone instead of standard-dose cytarabine with daunorubicin and 6-thioguanine: a randomized trial by the German AML Cooperative Group, Blood 1999;12:4116-24.
    • (1999) Blood , vol.12 , pp. 4116-4124
    • Buchner, T.1    Hiddemann, W.2    Wormann, B.3
  • 2
    • 9044228414 scopus 로고    scopus 로고
    • A randomized study of high-dose cytarabine in induction in acute myeloid leukemia
    • Bishop JF, Matthews JP, Young G A, et al. A randomized study of high-dose cytarabine in induction in acute myeloid leukemia. Blood 1996;5:1710-7.
    • (1996) Blood , vol.5 , pp. 1710-1717
    • Bishop, J.F.1    Matthews, J.P.2    Young, G.A.3
  • 3
    • 0026668478 scopus 로고
    • Varying intensity of postremission therapy in acute myeloid leukemia
    • Cassileth PA, Lynch E, Hines JD, et al. Varying intensity of postremission therapy in acute myeloid leukemia. Blood 1992;8:1924-30.
    • (1992) Blood , vol.8 , pp. 1924-1930
    • Cassileth, P.A.1    Lynch, E.2    Hines, J.D.3
  • 4
    • 0033975925 scopus 로고    scopus 로고
    • Multivariate analysis of prognostic factors in patients with refractory and relapsed acute myeloid leukemia undergoing sequential high-dose cytosine arabinoside and mitoxantrone (S-HAM) salvage therapy: Relevance of cytogenetic abnormalities
    • Kern W, Schoch C, Haferlach T, et al. Multivariate analysis of prognostic factors in patients with refractory and relapsed acute myeloid leukemia undergoing sequential high-dose cytosine arabinoside and mitoxantrone (S-HAM) salvage therapy: relevance of cytogenetic abnormalities. Leukemia 2000;2:226-31.
    • (2000) Leukemia , vol.2 , pp. 226-231
    • Kern, W.1    Schoch, C.2    Haferlach, T.3
  • 6
    • 0026623044 scopus 로고
    • A randomized study of intermediate versus conventional-dose cytarabine as intensive induction for acute myelogenous leukaemia
    • Schiller G, Gajewski J, Nimer S, et al. A randomized study of intermediate versus conventional-dose cytarabine as intensive induction for acute myelogenous leukaemia. Br J Haematol 1992;2:170-7.
    • (1992) Br J Haematol , vol.2 , pp. 170-177
    • Schiller, G.1    Gajewski, J.2    Nimer, S.3
  • 7
    • 10244249096 scopus 로고    scopus 로고
    • A randomized investigation of high-dose versus standard-dose cytosine arabinoside with daunorubicin in patients with previously untreated acute myeloid leukemia: A Southwest Oncology Group study
    • Weick JK, Kopecky KJ, Appelbaum FR, et al. A randomized investigation of high-dose versus standard-dose cytosine arabinoside with daunorubicin in patients with previously untreated acute myeloid leukemia: a Southwest Oncology Group study. Blood 1996;8:2841-51.
    • (1996) Blood , vol.8 , pp. 2841-2851
    • Weick, J.K.1    Kopecky, K.J.2    Appelbaum, F.R.3
  • 8
    • 0024351087 scopus 로고
    • In vitro pharmacodynamic assay for cancer drug development: Application to crisnatol, a new DNA intercalator
    • Adams DJ. In vitro pharmacodynamic assay for cancer drug development: application to crisnatol, a new DNA intercalator. Cancer Res 1989;23:6615-20.
    • (1989) Cancer Res , vol.23 , pp. 6615-6620
    • Adams, D.J.1
  • 9
    • 0032534995 scopus 로고    scopus 로고
    • Modeling of the time-dependency of in vitro drug cytotoxicity and resistance
    • Levasseur LM, Slocum HK, Rustum YM, Greco WR. Modeling of the time-dependency of in vitro drug cytotoxicity and resistance. Cancer Res 1998;24:5749-61.
    • (1998) Cancer Res , vol.24 , pp. 5749-5761
    • Levasseur, L.M.1    Slocum, H.K.2    Rustum, Y.M.3    Greco, W.R.4
  • 10
    • 0034100027 scopus 로고    scopus 로고
    • A pharmacodynamic analysis method to determine the relative importance of drug concentration and treatment time on effect
    • Millenbaugh NJ, Wientjes MG, Au JL. A pharmacodynamic analysis method to determine the relative importance of drug concentration and treatment time on effect. Cancer Chemother Pharmacol 2000;4:265-72.
    • (2000) Cancer Chemother Pharmacol , vol.4 , pp. 265-272
    • Millenbaugh, N.J.1    Wientjes, M.G.2    Au, J.L.3
  • 11
    • 27144494660 scopus 로고    scopus 로고
    • Sunnyvale (California): Molecular Devices Corp.
    • SOFTmax PRO: user manual. Version 2.4. Sunnyvale (California): Molecular Devices Corp.; 1998.
    • (1998) SOFTmax PRO: User Manual. Version 2.4
  • 12
    • 0027944021 scopus 로고
    • Carboplatin and granulocyte colony-stimulating factor as first-line treatment for epithelial ovarian cancer: A phase I dose-intensity escalation study
    • Calvert AH, Lind MJ, Ghazal-Aswad S, et al. Carboplatin and granulocyte colony-stimulating factor as first-line treatment for epithelial ovarian cancer: a phase I dose-intensity escalation study. Semin Oncol 1994;5 Suppl 12:1-6.
    • (1994) Semin Oncol , vol.5 , Issue.SUPPL. 12 , pp. 1-6
    • Calvert, A.H.1    Lind, M.J.2    Ghazal-Aswad, S.3
  • 13
    • 0023567452 scopus 로고
    • Pharmacokinetic studies of intermediate- to high-dose 1-β-D-arabinofuranosyl-cytosine in children with acute leukemia and lymphoma
    • Takashima Y, Matsuyama K. Pharmacokinetic studies of intermediate- to high-dose 1-β-D-arabinofuranosyl-cytosine in children with acute leukemia and lymphoma. J Clin Pharmacol 1987;4:330-3.
    • (1987) J Clin Pharmacol , vol.4 , pp. 330-333
    • Takashima, Y.1    Matsuyama, K.2
  • 14
    • 0023037493 scopus 로고
    • Low dose ara-C administered by continuous subcutaneous infusion: A pharmacologic evaluation
    • Spriggs DR, Sokal JE, Griffin J, Kufe DW. Low dose ara-C administered by continuous subcutaneous infusion: a pharmacologic evaluation. Cancer Drug Deliv 1986;3:211-6.
    • (1986) Cancer Drug Deliv , vol.3 , pp. 211-216
    • Spriggs, D.R.1    Sokal, J.E.2    Griffin, J.3    Kufe, D.W.4
  • 16
    • 0025648322 scopus 로고
    • High-dose versus intermediate-dose cytosine arabinoside in combination with mitoxantrone for the treatment of relapsed and refractory acute myeloid leukemia: Preliminary clinical and pharmacological data of a randomized comparison
    • Hiddemann W, Schleyer E, Uhrmeister C, et al. High-dose versus intermediate-dose cytosine arabinoside in combination with mitoxantrone for the treatment of relapsed and refractory acute myeloid leukemia: preliminary clinical and pharmacological data of a randomized comparison. Cancer Treat Rev 1990;2-3:279-85.
    • (1990) Cancer Treat Rev , vol.2-3 , pp. 279-285
    • Hiddemann, W.1    Schleyer, E.2    Uhrmeister, C.3
  • 17
    • 0022401865 scopus 로고
    • Pharmacokinetics of low-dose 1-β-D-arabinofuranosylcytosine given by continuous intravenous infusion over twenty-one days
    • Kreis W, Chaudhri F, Chan K, et al. Pharmacokinetics of low-dose 1-β-D-arabinofuranosylcytosine given by continuous intravenous infusion over twenty-one days. Cancer Res 1985;12 Pt 1:6498-501.
    • (1985) Cancer Res , vol.12 , Issue.PART 1 , pp. 6498-6501
    • Kreis, W.1    Chaudhri, F.2    Chan, K.3
  • 18
    • 0030838289 scopus 로고    scopus 로고
    • Pharmacokinetics of high-dose cytarabine and its deamination product: A reappraisal
    • Burk M, Heyll A, Arning M, Volmer M, Fartash K, Schneider W. Pharmacokinetics of high-dose cytarabine and its deamination product: a reappraisal. Leuk Lymphoma 1997;27:321-7.
    • (1997) Leuk Lymphoma , vol.27 , pp. 321-327
    • Burk, M.1    Heyll, A.2    Arning, M.3    Volmer, M.4    Fartash, K.5    Schneider, W.6
  • 19
    • 0025275742 scopus 로고
    • Randomized multicenter trial of cytosine arabinoside with mitoxantrone or daunorubicin in previously untreated adult patients with acute nonlymphocytic leukemia (ANLL)
    • Lederle Cooperative Group
    • Arlin Z, Case DC, Jr., Moore J, et al. Randomized multicenter trial of cytosine arabinoside with mitoxantrone or daunorubicin in previously untreated adult patients with acute nonlymphocytic leukemia (ANLL). Lederle Cooperative Group. Leukemia 1990;3:177-83.
    • (1990) Leukemia , vol.3 , pp. 177-183
    • Arlin, Z.1    Case Jr., D.C.2    Moore, J.3
  • 20
    • 11944275668 scopus 로고
    • Etoposide in acute nonlymphocytic leukemia
    • Australian Leukemia Study Group
    • Bishop JF, Lowenthal RM, Joshua D, et al. Etoposide in acute nonlymphocytic leukemia. Australian Leukemia Study Group. Blood 1990;1:27-32.
    • (1990) Blood , vol.1 , pp. 27-32
    • Bishop, J.F.1    Lowenthal, R.M.2    Joshua, D.3
  • 21
    • 0025079420 scopus 로고
    • Adult AML: The role of chemotherapy intensity and duration. Two studies of the AML Cooperative Group
    • Buchner T, Hiddemann W, Blasius S, et al. Adult AML: the role of chemotherapy intensity and duration. Two studies of the AML Cooperative Group. Hematol Blood Transfus 1990;261-6.
    • (1990) Hematol Blood Transfus , pp. 261-266
    • Buchner, T.1    Hiddemann, W.2    Blasius, S.3
  • 22
    • 0026717304 scopus 로고
    • Escalating the intensity of post-remission therapy improves the outcome in acute myeloid leukemia: The ECOG experience
    • The Eastern Cooperative Oncology Group
    • Cassileth PA, Andersen JW, Bennett JM, et al. Escalating the intensity of post-remission therapy improves the outcome in acute myeloid leukemia: the ECOG experience. The Eastern Cooperative Oncology Group. Leukemia 1992;6:116-9.
    • (1992) Leukemia , vol.6 , pp. 116-119
    • Cassileth, P.A.1    Andersen, J.W.2    Bennett, J.M.3
  • 23
    • 0025719792 scopus 로고
    • A comparative study of two different doses of cytarabine for acute myeloid leukemia: A phase III trial of Cancer and Leukemia Group B
    • Dillman RO, Davis RB, Green MR, et al. A comparative study of two different doses of cytarabine for acute myeloid leukemia: a phase III trial of Cancer and Leukemia Group B. Blood 1991;10:2520-6.
    • (1991) Blood , vol.10 , pp. 2520-2526
    • Dillman, R.O.1    Davis, R.B.2    Green, M.R.3
  • 24
    • 17344373829 scopus 로고    scopus 로고
    • Comparison between four and eight cycles of intensive chemotherapy in adult acute myeloid leukemia: A randomized trial of the Finnish Leukemia Group
    • Elonen E, Almqvist A, Hanninen A, et al. Comparison between four and eight cycles of intensive chemotherapy in adult acute myeloid leukemia: a randomized trial of the Finnish Leukemia Group. Leukemia 1998;7:1041-8.
    • (1998) Leukemia , vol.7 , pp. 1041-1048
    • Elonen, E.1    Almqvist, A.2    Hanninen, A.3
  • 25
    • 8244260076 scopus 로고    scopus 로고
    • Post-remission therapy of adult acute myeloid leukaemia: One cycle of high-dose versus standard-dose cytarabine
    • Leukaemia Project Group of the Swiss Group for Clinical Cancer Research (SAKK)
    • Fopp M, Fey MF, Bacchi M, et al. Post-remission therapy of adult acute myeloid leukaemia: one cycle of high-dose versus standard-dose cytarabine. Leukaemia Project Group of the Swiss Group for Clinical Cancer Research (SAKK). Ann Oncol 1997;3:251-7.
    • (1997) Ann Oncol , vol.3 , pp. 251-257
    • Fopp, M.1    Fey, M.F.2    Bacchi, M.3
  • 26
    • 0025732435 scopus 로고
    • Aclarubicin plus cytosine arabinoside versus daunorubicin plus cytosine arabinoside in previously untreated patients with acute myeloid leukemia: A Danish national phase III trial
    • The Danish Society of Hematology Study Group on AML, Denmark
    • Hansen OP, Pedersen-Bjergaard J, Ellegaard J, et al. Aclarubicin plus cytosine arabinoside versus daunorubicin plus cytosine arabinoside in previously untreated patients with acute myeloid leukemia: a Danish national phase III trial. The Danish Society of Hematology Study Group on AML, Denmark. Leukemia 1991;6:510-6.
    • (1991) Leukemia , vol.6 , pp. 510-516
    • Hansen, O.P.1    Pedersen-Bjergaard, J.2    Ellegaard, J.3
  • 27
    • 0028959505 scopus 로고
    • GM-CSF in a double-blind randomized, placebo controlled trial in therapy of adult patients with de novo acute myeloid leukemia (AML)
    • Heil G, Chadid L, Hoelzer D, et al. GM-CSF in a double-blind randomized, placebo controlled trial in therapy of adult patients with de novo acute myeloid leukemia (AML). Leukemia 1995;1:3-9.
    • (1995) Leukemia , vol.1 , pp. 3-9
    • Heil, G.1    Chadid, L.2    Hoelzer, D.3
  • 28
    • 0027978961 scopus 로고
    • Long-term outcome of postremission chemotherapy for adults with acute myeloid leukemia using different dose-intensities
    • Jehn U. Long-term outcome of postremission chemotherapy for adults with acute myeloid leukemia using different dose-intensities. Leuk Lymphoma 1994;1-2:99-112.
    • (1994) Leuk Lymphoma , vol.1-2 , pp. 99-112
    • Jehn, U.1
  • 29
    • 0030030928 scopus 로고    scopus 로고
    • Randomized trials between behenoyl cytarabine and cytarabine in combination induction and consolidation therapy, and with or without ubenimex after maintenance/intensification therapy in adult acute myeloid leukemia
    • The Japan Leukemia Study Group
    • Kobayashi T, Miyawaki S, Tanimoto M, et al. Randomized trials between behenoyl cytarabine and cytarabine in combination induction and consolidation therapy, and with or without ubenimex after maintenance/intensification therapy in adult acute myeloid leukemia. The Japan Leukemia Study Group. J Clin Oncol 1996;1:204-13.
    • (1996) J Clin Oncol , vol.1 , pp. 204-213
    • Kobayashi, T.1    Miyawaki, S.2    Tanimoto, M.3
  • 30
    • 0343045296 scopus 로고    scopus 로고
    • Mitoxantrone versus daunorubicin in induction-consolidation chemotherapy-the value of low-dose cytarabine for maintenance of remission, and an assessment of prognostic factors in acute myeloid leukemia in the elderly: Final report
    • European Organization for the Research and Treatment of Cancer and the Dutch-Belgian Hemato-Oncology Cooperative Hovon Group
    • Lowenberg B, Suciu S, Archimbaud E, et al. Mitoxantrone versus daunorubicin in induction-consolidation chemotherapy-the value of low-dose cytarabine for maintenance of remission, and an assessment of prognostic factors in acute myeloid leukemia in the elderly: final report. European Organization for the Research and Treatment of Cancer and the Dutch-Belgian Hemato-Oncology Cooperative Hovon Group. J Clin Oncol 1998;3:872-81.
    • (1998) J Clin Oncol , vol.3 , pp. 872-881
    • Lowenberg, B.1    Suciu, S.2    Archimbaud, E.3
  • 31
    • 0026593794 scopus 로고
    • A randomized study of the efficacy of postconsolidation therapy in adult acute nonlymphocytic leukemia: A report of the Italian Cooperative Group GIMEMA
    • Mandelli F, Vegna ML, Avvisati G, et al. A randomized study of the efficacy of postconsolidation therapy in adult acute nonlymphocytic leukemia: a report of the Italian Cooperative Group GIMEMA. Ann Hematol 1992;4:166-72.
    • (1992) Ann Hematol , vol.4 , pp. 166-172
    • Mandelli, F.1    Vegna, M.L.2    Avvisati, G.3
  • 32
    • 0027941369 scopus 로고
    • Intensive postremission chemotherapy in adults with acute myeloid leukemia
    • Cancer and Leukemia Group B
    • Mayer RJ, Davis RB, Schiffer CA, et al. Intensive postremission chemotherapy in adults with acute myeloid leukemia. Cancer and Leukemia Group B. N Engl J Med 1994;14:896-903.
    • (1994) N Engl J Med , vol.14 , pp. 896-903
    • Mayer, R.J.1    Davis, R.B.2    Schiffer, C.A.3
  • 33
    • 0028086285 scopus 로고
    • A randomized study of mitoxantrone plus cytarabine versus daunomycin plus cytarabine in the treatment of previously untreated adult patients with acute nonlymphocytic leukemia
    • Pavlovsky S, Gonzalez Llaven J, Garcia Martinez MA, et al. A randomized study of mitoxantrone plus cytarabine versus daunomycin plus cytarabine in the treatment of previously untreated adult patients with acute nonlymphocytic leukemia. Ann Hematol 1994;1:11-5.
    • (1994) Ann Hematol , vol.1 , pp. 11-15
    • Pavlovsky, S.1    Gonzalez Llaven, J.2    Garcia Martinez, M.A.3
  • 34
    • 8944247273 scopus 로고    scopus 로고
    • Treatment of acute myelogenous leukaemia in patients aged 50-65: Idarubicine is more effective than zorubicine for remission induction and prolonged disease-free survival can be obtained using a unique consolidation course
    • The Goelam Group
    • Pignon B, Witz F, Desablens B, et al. Treatment of acute myelogenous leukaemia in patients aged 50-65: idarubicine is more effective than zorubicine for remission induction and prolonged disease-free survival can be obtained using a unique consolidation course. The Goelam Group. Br J Haematol 1996;2:333-41.
    • (1996) Br J Haematol , vol.2 , pp. 333-341
    • Pignon, B.1    Witz, F.2    Desablens, B.3
  • 35
    • 9244253691 scopus 로고    scopus 로고
    • A prospective randomized trial of idarubicin vs daunorubicin in combination chemotherapy for acute myelogenous leukemia of the age group 55 to 75
    • Reiffers J, Huguet F, Stoppa AM, et al. A prospective randomized trial of idarubicin vs daunorubicin in combination chemotherapy for acute myelogenous leukemia of the age group 55 to 75. Leukemia 1996;3:389-95.
    • (1996) Leukemia , vol.3 , pp. 389-395
    • Reiffers, J.1    Huguet, F.2    Stoppa, A.M.3
  • 36
    • 0029015209 scopus 로고
    • A randomized placebo-controlled phase III study of granulocyte-macrophage colony-stimulating factor in adult patients (>55 to 70 years of age) with acute myelogenous leukemia: A study of the Eastern Cooperative Oncology Group (E1490)
    • Rowe JM, Andersen JW, Mazza JJ, et al. A randomized placebo-controlled phase III study of granulocyte-macrophage colony-stimulating factor in adult patients (>55 to 70 years of age) with acute myelogenous leukemia: a study of the Eastern Cooperative Oncology Group (E1490). Blood 1995;2:457-62.
    • (1995) Blood , vol.2 , pp. 457-462
    • Rowe, J.M.1    Andersen, J.W.2    Mazza, J.J.3
  • 37
    • 0043240289 scopus 로고    scopus 로고
    • Quinine as a multidrug resistance inhibitor: A phase 3 multicentric randomized study in adult de novo acute myelogenous leukemia
    • Epub 2003 Mar 27
    • Solary E, Drenou B, Campos L, et al. Quinine as a multidrug resistance inhibitor: a phase 3 multicentric randomized study in adult de novo acute myelogenous leukemia. Blood 2003;4:1202-10. Epub 2003 Mar 27.
    • (2003) Blood , vol.4 , pp. 1202-1210
    • Solary, E.1    Drenou, B.2    Campos, L.3
  • 38
    • 0025601754 scopus 로고
    • Therapy of acute myelogenous leukemia in patients over the age of 50: A randomized Southeastern Cancer Study Group trial
    • Stein RS, Vogler WR, Winton EF, Cohen HJ, Raney MR, Bartolucci A. Therapy of acute myelogenous leukemia in patients over the age of 50: a randomized Southeastern Cancer Study Group trial. Leuk Res 1990;10:895-903.
    • (1990) Leuk Res , vol.10 , pp. 895-903
    • Stein, R.S.1    Vogler, W.R.2    Winton, E.F.3    Cohen, H.J.4    Raney, M.R.5    Bartolucci, A.6
  • 39
    • 0025138479 scopus 로고
    • Low-dose cytarabine versus intensive chemotherapy in the treatment of acute nonlymphocytic leukemia in the elderly
    • Tilly H, Castaigne S, Bordessoule D, et al. Low-dose cytarabine versus intensive chemotherapy in the treatment of acute nonlymphocytic leukemia in the elderly. J Clin Oncol 1990;2:272-9.
    • (1990) J Clin Oncol , vol.2 , pp. 272-279
    • Tilly, H.1    Castaigne, S.2    Bordessoule, D.3
  • 40
    • 0026650021 scopus 로고
    • A phase III trial comparing idarubicin and daunorubicin in combination with cytarabine in acute myelogenous leukemia: A Southeastern Cancer Study Group Study
    • Vogler WR, Velez-Garcia E, Weiner RS, et al. A phase III trial comparing idarubicin and daunorubicin in combination with cytarabine in acute myelogenous leukemia: a Southeastern Cancer Study Group Study. J Clin Oncol 1992;7:1103-11.
    • (1992) J Clin Oncol , vol.7 , pp. 1103-1111
    • Vogler, W.R.1    Velez-Garcia, E.2    Weiner, R.S.3
  • 41
    • 0026586008 scopus 로고
    • Cytarabine plus idarubicin or daunorubicin as induction and consolidation therapy for previously untreated adult patients with acute myeloid leukemia
    • Wiernik PH, Banks PL, Case DC, Jr., et al. Cytarabine plus idarubicin or daunorubicin as induction and consolidation therapy for previously untreated adult patients with acute myeloid leukemia. Blood 1992;2:313-9.
    • (1992) Blood , vol.2 , pp. 313-319
    • Wiernik, P.H.1    Banks, P.L.2    Case Jr., D.C.3
  • 42
    • 0042967809 scopus 로고    scopus 로고
    • Effect of priming with granulocyte colony-stimulating factor on the outcome of chemotherapy for acute myeloid leukemia
    • Lowenberg B, van Putten W, Theobald M, et al. Effect of priming with granulocyte colony-stimulating factor on the outcome of chemotherapy for acute myeloid leukemia. N Engl J Med 2003;8:743-52.
    • (2003) N Engl J Med , vol.8 , pp. 743-752
    • Lowenberg, B.1    Van Putten, W.2    Theobald, M.3
  • 43
    • 0023356575 scopus 로고
    • Saturation of ara-CTP formation during high-dose ara-c therapy: Pharmacological rationale for intermediate-dose ara-c
    • Plunkett W, Liliemark JO, Estey E, Keating M. Saturation of ara-CTP formation during high-dose ara-c therapy: pharmacological rationale for intermediate-dose ara-c. Semin Oncol 1987;2:159-66.
    • (1987) Semin Oncol , vol.2 , pp. 159-166
    • Plunkett, W.1    Liliemark, J.O.2    Estey, E.3    Keating, M.4
  • 44
    • 0027450455 scopus 로고
    • Fludarabine potentiates metabolism of cytarabine in patients with acute myelogenous leukemia during therapy
    • GandhiV, Estey E, Keating MJ, Plunkett W. Fludarabine potentiates metabolism of cytarabine in patients with acute myelogenous leukemia during therapy. J Clin Oncol 1993;1:116-24.
    • (1993) J Clin Oncol , vol.1 , pp. 116-124
    • Gandhi, V.1    Estey, E.2    Keating, M.J.3    Plunkett, W.4
  • 45
    • 0025008675 scopus 로고
    • Cellular ara-CTP pharmacokinetics, response, and karyotype in newly diagnosed acute myelogenous leukemia
    • Estey E, Keating M, McCredie K, Freireich EJ, Plunkett W. Cellular ara-CTP pharmacokinetics, response, and karyotype in newly diagnosed acute myelogenous leukemia. Leukemia 1990;2:95-9.
    • (1990) Leukemia , vol.2 , pp. 95-99
    • Estey, E.1    Keating, M.2    McCredie, K.3    Freireich, E.J.4    Plunkett, W.5
  • 46
    • 0023470734 scopus 로고
    • Variables predicting response to high-dose cytosine arabinoside therapy in patients with refractory acute leukemia
    • Estey E, Plunkett W, Dixon D, Keating M, McCredie K, Freireich EJ. Variables predicting response to high-dose cytosine arabinoside therapy in patients with refractory acute leukemia. Leukemia 1987;8:580-3.
    • (1987) Leukemia , vol.8 , pp. 580-583
    • Estey, E.1    Plunkett, W.2    Dixon, D.3    Keating, M.4    McCredie, K.5    Freireich, E.J.6
  • 47
    • 0035096825 scopus 로고    scopus 로고
    • Simulation tool for schedule-dependent etoposide exposure based on pharmacokinetic findings published in the literature
    • Wurthwein G, Boos J. Simulation tool for schedule-dependent etoposide exposure based on pharmacokinetic findings published in the literature. Anticancer Drugs 2001;2:151-8.
    • (2001) Anticancer Drugs , vol.2 , pp. 151-158
    • Wurthwein, G.1    Boos, J.2
  • 48
    • 0036206925 scopus 로고    scopus 로고
    • Low dose-high dose: What is the right dose? Pharmacokinetic modeling of etoposide
    • Epub 2002 Jan 30
    • Wurthwein G, Boos J. Low dose-high dose: what is the right dose? Pharmacokinetic modeling of etoposide. Cancer Chemother Pharmacol 2002;4:303-8. Epub 2002 Jan 30.
    • (2002) Cancer Chemother Pharmacol , vol.4 , pp. 303-308
    • Wurthwein, G.1    Boos, J.2
  • 49
    • 3042806865 scopus 로고    scopus 로고
    • Relevance of pathological classifications and diagnosis of acute myeloid leukemia to clinical trials and clinical practice
    • Tallman MS. Relevance of pathological classifications and diagnosis of acute myeloid leukemia to clinical trials and clinical practice. Cancer Treat Res 2004;45-67.
    • (2004) Cancer Treat Res , pp. 45-67
    • Tallman, M.S.1
  • 50
    • 1842614240 scopus 로고    scopus 로고
    • Repetitive cycles of high-dose cytarabine benefit patients with acute myeloid leukemia and inv(16)(p13q22) or T(16;16)(p13;q23): Results from CALGB 8461
    • Byrd JC, Ruppert AS, Mrozek K, et al. Repetitive cycles of high-dose cytarabine benefit patients with acute myeloid leukemia and inv(16)(p13q22) or T(16;16)(p13;q23): results from CALGB 8461. J Clin Oncol 2004;6:1087-94.
    • (2004) J Clin Oncol , vol.6 , pp. 1087-1094
    • Byrd, J.C.1    Ruppert, A.S.2    Mrozek, K.3
  • 51
    • 0032793987 scopus 로고    scopus 로고
    • Patients with t(8;21)(q22;q22) and acute myeloid leukemia have superior failure-free and overall survival when repetitive cycles high-dose cytarabine are administered
    • Byrd JC, Dodge RK, Carroll AJ, et al. Patients with t(8;21)(q22;q22) and acute myeloid leukemia have superior failure-free and overall survival when repetitive cycles high-dose cytarabine are administered. J Clin Oncol 1999;12:3767-75.
    • (1999) J Clin Oncol , vol.12 , pp. 3767-3775
    • Byrd, J.C.1    Dodge, R.K.2    Carroll, A.J.3
  • 52
    • 0035135876 scopus 로고    scopus 로고
    • Patients with de-novo acute myeloid leukemia and complex karyotype aberrations have a poor prognosis despite intensive treatment: A study of 90 patients
    • Schoch C, Haferlach T, Haase D, et al. Patients with de-novo acute myeloid leukemia and complex karyotype aberrations have a poor prognosis despite intensive treatment: a study of 90 patients. Br J Haematol 2001;1:118-26.
    • (2001) Br J Haematol , vol.1 , pp. 118-126
    • Schoch, C.1    Haferlach, T.2    Haase, D.3
  • 54
    • 0025696765 scopus 로고
    • A phase I study of intermittent continuous infusion high dose cytosine arabinoside for acute leukemia
    • Stone RM, Spriggs D, Dhawan RK, Arthur KA, Mayer RJ, Kufe D. A phase I study of intermittent continuous infusion high dose cytosine arabinoside for acute leukemia. Leukemia 1990;12:843-7.
    • (1990) Leukemia , vol.12 , pp. 843-847
    • Stone, R.M.1    Spriggs, D.2    Dhawan, R.K.3    Arthur, K.A.4    Mayer, R.J.5    Kufe, D.6
  • 55
    • 0027716345 scopus 로고
    • Phase I study of a continuous infusion of high-dose ara-C in conjunction with a fixed dose of 2′-deoxycytidine (IND 28108) in patients with refractory leukemia: An interim report
    • Grant S, Baker M, Bhalla K. Phase I study of a continuous infusion of high-dose ara-C in conjunction with a fixed dose of 2′-deoxycytidine (IND 28108) in patients with refractory leukemia: an interim report. Leukemia 1993;12:1933-8.
    • (1993) Leukemia , vol.12 , pp. 1933-1938
    • Grant, S.1    Baker, M.2    Bhalla, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.