Arylzinc species by microwave assisted Grignard formation-transmetallation sequence: Application in the Negishi coupling

Tetrahedron

Volumn 61, Issue 47, 2005, Pages 11168-11176

  Mutule, Ilga ^a   Suna, Edgars ^a  

^a LATVIAN INSTITUTE OF ORGANIC SYNTHESIS   (Latvia)

Author keywords

Grignard reagents; Microwaves; Negishi coupling; Organozinc reagents; Transmetallation

Indexed keywords

MAGNESIUM DERIVATIVE; ZINC DERIVATIVE;

ARTICLE; AUTOMATION; CHEMICAL REACTION; CONCENTRATION (PARAMETERS); GRIGNARD REACTION; METALLATION; MICROWAVE RADIATION; NEGISHI CROSS COUPLING; PRIORITY JOURNAL; SYNTHESIS; TEMPERATURE;

EID: 27144473377     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2005.09.022     Document Type: Article

References (36)

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16. 2O, which are a routinely used medium for preparation of Grignard reagents. We were pleased to find that temperature and pressure profiles of the heating did not show any unusual behavior such as quick rise of temperature or sudden change of pressure, demonstrating that microwave irradiation of magnesium turnings under the tested conditions is safe and reliable procedure.
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