Synthesis of 1,2-benzisothiazolyloxypropanolamine derivatives and investigation of their activity at β-adrenoceptors

Farmaco

Volumn 60, Issue 10, 2005, Pages 810-817

  Morini, Giovanni ^a   Pozzoli, Cristina ^a   Menozzi, Alessandro ^a   Comini, Mara ^a   Poli, Enzo ^a  

^a UNIVERSITY OF PARMA   (Italy)

Author keywords

; Adrenoceptors; Benzisothiazoloxypropanolamines; Rat atria; Rat bladder; Rat intestine

Indexed keywords

1 (3 METHOXYBENZ[D]ISOTHIAZOL 5 YLOXY) 3 PHENETHYLAMINOPROPAN 2 OL; 1 [(BENZO[1,3]DIOXOL 5 YLMETHYL)AMINO] 3 (3 METHOXYBENZ[D]ISOTHIAZOL 5 YLOXY)PROPAN 2 OL; 1 [(BENZO[1,3]DIOXOL 5 YLMETHYL)AMINO] 3 (3 METHOXYBENZ[D]ISOTHIAZOL 7 YLOXY)PROPAN 2 OL; 1 BENZYLAMINO 3 (3 METHOXYBENZ[D]ISOTHIAZOL 5 YLOXY)PRPAN 2 OL; 1 BENZYLAMINO 3 (3 METHOXYBENZ[D]ISOTHIAZOL 7 YLOXY)PROPAN 2 OL; 1 CYCLOHEXYLAMINO 3 (3 METHOXYBENZ[D]ISOTHIAZOL 5 YLOXY)PROPAN 2 OL; 1 CYCLOHEXYLAMINO 3 (3 METHOXYBENZ[D]ISOTHIAZOL 7 YLOXY)PROPAN 2 OL; 1 ISOPROPYLAMINO 3 (3 METHOXYBENZ[D]ISOTHIAZOL 5 YLOXY)PROPAN 2 OL; 1 ISOPROPYLAMINO 3 (3 METHOXYBENZ[D]ISOTHIAZOL 7 YLOXY)PROPAN 2 OL; 3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 4 [2 HYDROXY 3 (3 METHOXYBENZ[D]ISOTHIAZOL 5 YLOXY)PROPYLAMINO]PIPERIDINE 1 SULFINIC ACID 4 METHOXYPHENYL ESTER; 4 [2 HYDROXY 3 (3 METHOXYBENZ[D]ISOTHIAZOL 7 YLOXYPROPYLAMINO]PIPERIDINE 1 SULFINIC ACID 4 METHOXYPHENYL ESTER; [4 [2 [2 HYDROXY 3 (3 METHOXYBENZ[D]ISOTHIAZOL 5 YLOXY)PROPYLAMINO]ETHYL] PHENYL]SULFINAMIC ACID 4 METHOXYPHENYL ESTER; [4 [2 [2 HYDROXY 3 (3 METHOXYBENZ[D]ISOTHIAZOL 7 YLOXY)PROPYLAMINO]ETHYL] PHENYL]SULFINAMIC ACID 4 METHOXYPHENYL ESTER; BENZOTHIAZOLE DERIVATIVE; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BUPRANOLOL; ISOPRENALINE; PROPANOLAMINE DERIVATIVE; PROPIONIC ACID DERIVATIVE; PROPRANOLOL; RECEPTOR SUBTYPE; SPASMOLYTIC AGENT; UNCLASSIFIED DRUG;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BLADDER; CALCIUM CELL LEVEL; CELL MEMBRANE; CHRONOTROPISM; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BINDING SITE; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; HEART ATRIUM; MALE; NONHUMAN; RAT; RECEPTOR BINDING; RECEPTOR DENSITY; RECEPTOR INTRINSIC ACTIVITY; SMALL INTESTINE; SMOOTH MUSCLE RELAXATION;

ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; MOLECULAR STRUCTURE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 26944503435     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.farmac.2005.07.008     Document Type: Article

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