Synthesis and characterizations of biodegradable and crosslinkable poly(ε-caprolactone fumarate), poly(ethylene glycol fumarate), and their amphiphilic copolymer

Biomaterials

Volumn 27, Issue 6, 2006, Pages 832-841

  Wang, Shanfeng ^a   Lu, Lichun ^a   Gruetzmacher, James A ^a   Currier, Bradford L ^a   Yaszemski, Michael J ^a  

^a Mayo Clinic   (United States)

Author keywords

Amphiphilic polymer network; Cross linking; Polycaprolactone; Polyethylene oxide; Polymerization

Indexed keywords

BIODEGRADATION; BIOMEDICAL ENGINEERING; CHEMICAL BONDS; CROSSLINKING; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYMERIZATION; SYNTHESIS (CHEMICAL); TISSUE;

AMPHIPHILIC POLYMER NETWORKS; BIODEGRADABLE POLYMERS; POLYCAPROLACTONE; TISSUE ENGINEERING;

COPOLYMERS;

COPOLYMER; FUMARIC ACID DIMETHYL ESTER; MACROGOL; POLYCAPROLACTONE; POTASSIUM CARBONATE; SCAVENGER; TRIETHYLAMINE;

ARTICLE; BIODEGRADABILITY; CHEMICAL BOND; CHEMICAL STRUCTURE; CROSS LINKING; PRIORITY JOURNAL; STRUCTURE ANALYSIS; SYNTHESIS; TISSUE ENGINEERING;

BIOCOMPATIBLE MATERIALS; BIODEGRADATION, ENVIRONMENTAL; CALORIMETRY, DIFFERENTIAL SCANNING; CROSS-LINKING REAGENTS; FUMARATES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; POLYESTERS; POLYETHYLENE GLYCOLS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TEMPERATURE; VISCOSITY;

EID: 26944487609     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2005.07.013     Document Type: Article

References (20)

1. A.P.D. Elfick Poly(ε-caprolactone) as a potential material for a temporary joint spacer Biomaterials 23 2002 4463 4467
2. K.W. Ng, D.W. Hutmacher, J.T. Schantz, C.S. Ng, H.P. Too, T.C. Lim, T.T. Phan, and S.H. Teoh Evaluation of ultra-thin poly(ε-caprolactone) films for tissue-engineered skin Tissue Eng 7 2001 441 455
3. H.Y. Kweon, M.K. Yoo, I.K. Park, T.H. Kim, H.C. Lee, H.S. Lee, J.S. Oh, T. Akaike, and C.S. Cho A novel degradable polycaprolactone networks for tissue engineering Biomaterials 24 2003 801
4. M.P.K. Turunen, H. Korhonen, J. Tuominen, and J.V. Seppala Synthesis, characterization and crosslinking of functional star-shaped poly(ε- caprolactone) Polym Int 51 2001 92 100
5. E. Jabbari, S.F. Wang, L.C. Lu, J.A. Gruetzmacher, S. Ameenuddin, T.E. Hefferan, B.L. Currier, A.J. Windebank, and M.J. Yaszemski Synthesis, material properties and biocompatibility of a novel self-crosslinkable poly(caprolactone fumarate) as an injectable tissue engineering scaffold Biomacromolecules 2005 in press
6. S. Jo, H. Shin, A.K. Shung, J.P. Fisher, and A.G. Mikos Synthesis and characterization of oligo(poly(ethylene glycol) fumarate) macromer Macromolecules 34 2001 2839
7. J.S. Temenoff, K.A. Athanasiou, R.G. LeBaron, and A.G. Mikos Effect of poly(ethylene glycol) molecular weight on tensile and swelling properties of oligo(poly(ethylene glycol) fumarate) hydrogels for cartilage tissue engineering J Biomed Mater Res 59 2002 429
8. H. Shin, S. Jo, and A.G. Mikos Modulation of marrow stromal osteoblast adhesion on biomimetic oligo[poly(ethylene glycol) fumarate] hydrogels modified with Arg-Gly Asp peptides and a poly(ethylene glycol) spacer J Biomed Mater Res 61 2002 169
9. S. Jo, H. Shin, and A.G. Mikos Modification of oligo(poly(ethylene glycol) fumarate) macromer with a GRGD peptide for the preparation of functionalized polymer networks Biomacromolecules 2 2001 255 261
10. Y. Zhang, C.-Y. Won, and C.-C. Chu Synthesis and characterization of biodegradable network hydrogels having both hydrophobic and hydrophilic components with controlled swelling behavior J Polym Sci Part A Polym Chem 37 1999 4554 4569
11. Y. Zhang, C.-Y. Won, and C.-C. Chu Synthesis and characterization of biodegradable hydrophobic-hydrophilic hydrogel network with controlled swelling behavior J Polym Sci Part A Polym Chem 37 1999 4554 4569
12. K.K. Jette, D. Law, E.A. Schmitt, and G.S. Kwon Preparation and drug loading of poly(ethylene glycol)-block-poly(ε-caprolactone) micelles through the evaporation of a cosolvent azeotrope Pham Res 21 7 2004 1184 1191
13. K.S. Anseth, V.R. Shastri, and R. Langer Photopolymerizable degradable polyanhydrides with osteocompatibility Nature Biotechnol 17 1999 156 159
14. S.J. Peter, L.J. Suggs, M.J. Yaszemski, P.S. Engel, and A.G. Mikos Synthesis of Poly(propylene fumarate) by acrylation of propylene glycol in the presence of a proton scavenger J Biomater Sci Polymer Edn 10 3 1999 363
15. L.J. Suggs, R.G. Payne, M.J. Yaszemski, L.B. Alemany, and A.G. Mikos Synthesis and characterization of a block copolymer consisting of poly(propylene fumarate) and poly(ethylene glycol) Macromolecules 30 1997 4318
16. J. Brandrup E.H. Immergut Polymer handbook 3rd ed 1989 Wiley New York
17. E.L. Chaikof, and E.W. Merrill Bulk properties of poly(ethylene oxide)/polysiloxane networks New Polym Mater 2 1990 125 147
18. D.E. Perrin, and J.P. English Polycaprolactone A.J. Domb J. Kost D. Wiseman Handbook of biodegradable polymers 1997 Harwood Academic Publishers Amsterdam
19. H. Ge, Y. Hu, X. Jiang, D. Cheng, Y. Yuan, H. Bi, and C. Yang Preparation, characterization, and drug release behaviors of drug Nimodine-loaded poly(ε-caprolactone)-b-poly(ethylene glycol)-b-poly(ε- caprolactone) amphiphilic triblock copolymer micelles J Pharm Sci 91 2002 1463 1473
20. Y. Hu, L. Zhang, Y. Cao, H. Ge, X. Jiang, and C. Yang Degradation behavior of poly(ε-caprolactone)-b-poly(ethylene glycol)-b-poly(ε- caprolactone) micelles in aquesous solution Biomacromolecules 5 2004 1756 1762