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Volumn 37, Issue 6, 2005, Pages 381-388

Colonic targeting of aminosalicylates for the treatment of ulcerative colitis

Author keywords

Aminosalicylates; Drug targeting; Prodrugs; Ulcerative colitis

Indexed keywords

5 ACETAMIDOSALICYLIC ACID; AMINOSALICYLIC ACID DERIVATIVE; AMPICILLIN; ANTIDIARRHEAL AGENT; ANTIINFLAMMATORY AGENT; BALSALAZIDE; DERSALAZINE; EUDRAGIT; FAMOTIDINE; HISTAMINE H2 RECEPTOR ANTAGONIST; MESALAZINE; NCX 456; NITRIC OXIDE MESALAMINE; OLSALAZINE; OMEPRAZOLE; PLACEBO; PROTON PUMP INHIBITOR; SALAZOSULFAPYRIDINE; SULFAPYRIDINE; UNCLASSIFIED DRUG; UR 12746S; URSODEOXYCHOLIC ACID MESALAZINE CONJUGATE; NONSTEROID ANTIINFLAMMATORY AGENT; PRODRUG;

EID: 26944479743     PISSN: 15908658     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dld.2004.12.011     Document Type: Short Survey
Times cited : (43)

References (77)
  • 1
    • 84982333870 scopus 로고
    • Salazopyrin-a new sulfanilamide preparation. A. Therapeutic result in rheumatoid arthritis. B. Therapeutic results in ulcerative colitis. C. Toxic manifestations on treatment with sulfanilamide preparations
    • Svartz N. Salazopyrin-a new sulfanilamide preparation. A. Therapeutic result in rheumatoid arthritis. B. Therapeutic results in ulcerative colitis. C. Toxic manifestations on treatment with sulfanilamide preparations. Acta Med Scand 110 (1942) 577-590
    • (1942) Acta Med Scand , vol.110 , pp. 577-590
    • Svartz, N.1
  • 2
    • 84920223116 scopus 로고
    • An experiment to determine the active therapeutic moiety of sulphasalazine
    • Azad Khan A.K., Piris J., and Truelove S.C. An experiment to determine the active therapeutic moiety of sulphasalazine. Lancet II (1977) 892-895
    • (1977) Lancet , vol.II , pp. 892-895
    • Azad Khan, A.K.1    Piris, J.2    Truelove, S.C.3
  • 3
    • 0018961746 scopus 로고
    • Effect of sulphapyridine, 5-aminosalicylic acid, and placebo in patients with idiopathic proctitis: a study to determine the active therapeutic moiety of sulphasalazine
    • Van Hees P.A.M., Bakker J.H., and Van Tongeren J.H.M. Effect of sulphapyridine, 5-aminosalicylic acid, and placebo in patients with idiopathic proctitis: a study to determine the active therapeutic moiety of sulphasalazine. Gut 21 (1980) 632-635
    • (1980) Gut , vol.21 , pp. 632-635
    • Van Hees, P.A.M.1    Bakker, J.H.2    Van Tongeren, J.H.M.3
  • 4
    • 0019204911 scopus 로고
    • Therapeutic efficacy of sulfasalazine and its metabolites in patients with ulcerative colitis and Crohn's disease
    • Klotz U., Maier K., Fischer C.L., and Heinkel K. Therapeutic efficacy of sulfasalazine and its metabolites in patients with ulcerative colitis and Crohn's disease. N Engl J Med 303 (1980) 1499-1502
    • (1980) N Engl J Med , vol.303 , pp. 1499-1502
    • Klotz, U.1    Maier, K.2    Fischer, C.L.3    Heinkel, K.4
  • 5
    • 0015916139 scopus 로고
    • Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype
    • Das K.M., Eastwood M.A., McManus J.P.A., and Sircus W. Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype. N Engl J Med 289 (1973) 491-495
    • (1973) N Engl J Med , vol.289 , pp. 491-495
    • Das, K.M.1    Eastwood, M.A.2    McManus, J.P.A.3    Sircus, W.4
  • 6
    • 0018974780 scopus 로고
    • Is plasma level monitoring of sulfasalazine indicated in the treatment of Crohn's disease or ulcerative colitis?
    • Fischer C., and Klotz U. Is plasma level monitoring of sulfasalazine indicated in the treatment of Crohn's disease or ulcerative colitis?. Ther Drug Monit 2 (1980) 153-158
    • (1980) Ther Drug Monit , vol.2 , pp. 153-158
    • Fischer, C.1    Klotz, U.2
  • 7
    • 0021806456 scopus 로고
    • Clinical pharmacokinetics of sulphasalazine, its metabolites and other prodrugs of 5-aminosalicylic acid
    • Klotz U. Clinical pharmacokinetics of sulphasalazine, its metabolites and other prodrugs of 5-aminosalicylic acid. Clin Pharmacokinet 10 (1985) 285-302
    • (1985) Clin Pharmacokinet , vol.10 , pp. 285-302
    • Klotz, U.1
  • 8
    • 0037043658 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • Podolsky D. Inflammatory bowel disease. N Engl J Med 347 (2002) 417-429
    • (2002) N Engl J Med , vol.347 , pp. 417-429
    • Podolsky, D.1
  • 9
    • 0037176571 scopus 로고    scopus 로고
    • Ulcerative colitis
    • Farrell R., and Peppercorn M.A. Ulcerative colitis. Lancet 359 (2002) 331-340
    • (2002) Lancet , vol.359 , pp. 331-340
    • Farrell, R.1    Peppercorn, M.A.2
  • 11
    • 0034061366 scopus 로고    scopus 로고
    • A meta-analysis and overview of the literature on treatment options for left-sided ulcerative colitis and ulcerative proctitis
    • Cohen R.D., Woseth D.M., Thistel R.A., and Hanauer S.B. A meta-analysis and overview of the literature on treatment options for left-sided ulcerative colitis and ulcerative proctitis. Am J Gastroenterol 95 (2000) 1263-1276
    • (2000) Am J Gastroenterol , vol.95 , pp. 1263-1276
    • Cohen, R.D.1    Woseth, D.M.2    Thistel, R.A.3    Hanauer, S.B.4
  • 12
    • 0038574374 scopus 로고    scopus 로고
    • Review article: medical treatment of severe ulcerative colitis
    • Rizzello F., Gionchetti P., Venturi A., and Campieri M. Review article: medical treatment of severe ulcerative colitis. Aliment Pharmacol Ther 17 Suppl. 2 (2003) 7-10
    • (2003) Aliment Pharmacol Ther , vol.17 , Issue.SUPPL. 2 , pp. 7-10
    • Rizzello, F.1    Gionchetti, P.2    Venturi, A.3    Campieri, M.4
  • 13
    • 0036897124 scopus 로고    scopus 로고
    • Rational selection of oral 5-aminosalicylate formulations and prodrugs for the treatment of ulcerative colitis
    • Sandborn W.J. Rational selection of oral 5-aminosalicylate formulations and prodrugs for the treatment of ulcerative colitis. Am J Gastroenterol 97 (2002) 2939-2941
    • (2002) Am J Gastroenterol , vol.97 , pp. 2939-2941
    • Sandborn, W.J.1
  • 14
    • 0036230391 scopus 로고    scopus 로고
    • New steroids and new salicylates in inflammatory bowel disease: a critical appraisal
    • Campieri M. New steroids and new salicylates in inflammatory bowel disease: a critical appraisal. Gut 50 Suppl. III (2002) iii43-iii46
    • (2002) Gut , vol.50 , Issue.SUPPL. III
    • Campieri, M.1
  • 15
    • 0036080280 scopus 로고    scopus 로고
    • Long-term maintenance treatment in ulcerative colitis: a 10-year follow up study
    • Bresci G., Parisi G., Bertoni M., and Capria A. Long-term maintenance treatment in ulcerative colitis: a 10-year follow up study. Dig Liver Dis 34 (2002) 419-423
    • (2002) Dig Liver Dis , vol.34 , pp. 419-423
    • Bresci, G.1    Parisi, G.2    Bertoni, M.3    Capria, A.4
  • 16
    • 0034923640 scopus 로고    scopus 로고
    • 5-Aminosalicylates in inflammatory bowel disease: choosing the right dose
    • Qasim A., Seery J., and O'Morain C.A. 5-Aminosalicylates in inflammatory bowel disease: choosing the right dose. Dig Liver Dis 323 (2001) 393-398
    • (2001) Dig Liver Dis , vol.323 , pp. 393-398
    • Qasim, A.1    Seery, J.2    O'Morain, C.A.3
  • 17
    • 0034765504 scopus 로고    scopus 로고
    • Pharmacokinetic considerations in the treatment of inflammatory bowel disease
    • Schwab M., and Klotz U. Pharmacokinetic considerations in the treatment of inflammatory bowel disease. Clin Pharmacokinet 40 (2001) 723-751
    • (2001) Clin Pharmacokinet , vol.40 , pp. 723-751
    • Schwab, M.1    Klotz, U.2
  • 18
    • 0037249395 scopus 로고    scopus 로고
    • Assessment of orocaecal transit time in different localization of Crohn's disease and its possible influence on clinical response to therapy
    • Tursi A., Brandimarte G., Giorgetti G.M., and Nasi G. Assessment of orocaecal transit time in different localization of Crohn's disease and its possible influence on clinical response to therapy. Eur J Gastroenterol Hepatol 15 (2003) 69-74
    • (2003) Eur J Gastroenterol Hepatol , vol.15 , pp. 69-74
    • Tursi, A.1    Brandimarte, G.2    Giorgetti, G.M.3    Nasi, G.4
  • 19
    • 0033991846 scopus 로고    scopus 로고
    • Changes in intestinal transit time after proctocolectomy assessed by the lactulose breath test
    • Bruewer M., Stern J., Herrman S., Senninger N., and Herfarth C. Changes in intestinal transit time after proctocolectomy assessed by the lactulose breath test. World J Surg 24 (2000) 119-124
    • (2000) World J Surg , vol.24 , pp. 119-124
    • Bruewer, M.1    Stern, J.2    Herrman, S.3    Senninger, N.4    Herfarth, C.5
  • 20
    • 0035084176 scopus 로고    scopus 로고
    • Intestinal luminal pH in inflammatory bowel disease: possible determinants and implications for therapy with aminosalicylates and other drugs
    • Nugent S.G., Kumar D., Rampton D.S., and Evans D.F. Intestinal luminal pH in inflammatory bowel disease: possible determinants and implications for therapy with aminosalicylates and other drugs. Gut 48 (2001) 571-577
    • (2001) Gut , vol.48 , pp. 571-577
    • Nugent, S.G.1    Kumar, D.2    Rampton, D.S.3    Evans, D.F.4
  • 22
    • 0032999413 scopus 로고    scopus 로고
    • Intraluminal pH of the human gastrointestinal tract
    • Fallingborg J. Intraluminal pH of the human gastrointestinal tract. Dan Med Bull 46 (1999) 183-196
    • (1999) Dan Med Bull , vol.46 , pp. 183-196
    • Fallingborg, J.1
  • 23
    • 0032892265 scopus 로고    scopus 로고
    • Prevention of postoperative recurrence of Crohn's disease requires adequate mucosal concentrations of mesalazine
    • Frieri G., Pimpo M.T., Andreoli A., Annese V., Comberlato M., Corrao G., et al. Prevention of postoperative recurrence of Crohn's disease requires adequate mucosal concentrations of mesalazine. Aliment Pharmacol Ther 13 (1999) 557-582
    • (1999) Aliment Pharmacol Ther , vol.13 , pp. 557-582
    • Frieri, G.1    Pimpo, M.T.2    Andreoli, A.3    Annese, V.4    Comberlato, M.5    Corrao, G.6
  • 24
    • 0033850139 scopus 로고    scopus 로고
    • Mucosal 5-aminosalicylic acid concentrations inversely correlate with severity of colonic inflammation in patients with ulcerative colitis
    • Frieri G., Giacomelli G., Pimpo M., Palumbo G., Passacantando A., Pantaleoni G., et al. Mucosal 5-aminosalicylic acid concentrations inversely correlate with severity of colonic inflammation in patients with ulcerative colitis. Gut 47 (2000) 410-414
    • (2000) Gut , vol.47 , pp. 410-414
    • Frieri, G.1    Giacomelli, G.2    Pimpo, M.3    Palumbo, G.4    Passacantando, A.5    Pantaleoni, G.6
  • 25
    • 0034890464 scopus 로고    scopus 로고
    • Measurement of colonic mucosal concentrations of 5-aminosalicylic acid is useful for estimating its therapeutic efficacy in distal ulcerative colitis: comparison of orally administered mesalamine and sulfasalazine
    • Naganuma M., Iwao Y., Ogata H., Inoue N., Funakoshi S., Yamamoto S., et al. Measurement of colonic mucosal concentrations of 5-aminosalicylic acid is useful for estimating its therapeutic efficacy in distal ulcerative colitis: comparison of orally administered mesalamine and sulfasalazine. Inflamm Bowel Dis 7 (2001) 221-225
    • (2001) Inflamm Bowel Dis , vol.7 , pp. 221-225
    • Naganuma, M.1    Iwao, Y.2    Ogata, H.3    Inoue, N.4    Funakoshi, S.5    Yamamoto, S.6
  • 26
    • 0026784770 scopus 로고
    • Concentrations of 5-ASA and Ac-5-ASA in human ileocolonic biopsy homogenates after oral 5-ASA preparations
    • De Vos M., Verdievel H., Schoonjans R., Praet M., Bogaert M., and Barbier F. Concentrations of 5-ASA and Ac-5-ASA in human ileocolonic biopsy homogenates after oral 5-ASA preparations. Gut 33 (1992) 1338-1342
    • (1992) Gut , vol.33 , pp. 1338-1342
    • De Vos, M.1    Verdievel, H.2    Schoonjans, R.3    Praet, M.4    Bogaert, M.5    Barbier, F.6
  • 27
    • 0033839408 scopus 로고    scopus 로고
    • The role of aminosalicylates at the beginning of the new millennium in the treatment of chronic inflammatory bowel disease
    • Klotz U. The role of aminosalicylates at the beginning of the new millennium in the treatment of chronic inflammatory bowel disease. Eur J Clin Pharmacol 56 (2000) 353-362
    • (2000) Eur J Clin Pharmacol , vol.56 , pp. 353-362
    • Klotz, U.1
  • 28
    • 0036119573 scopus 로고    scopus 로고
    • Role of 5-aminosalicylic acid (5-ASA) in treatment of inflammatory bowel disease. A systematic review
    • Gisbert J.P., Gomollón F., Maté J., and Pajares J.M. Role of 5-aminosalicylic acid (5-ASA) in treatment of inflammatory bowel disease. A systematic review. Dig Dis Sci 47 (2002) 471-488
    • (2002) Dig Dis Sci , vol.47 , pp. 471-488
    • Gisbert, J.P.1    Gomollón, F.2    Maté, J.3    Pajares, J.M.4
  • 29
    • 0033944708 scopus 로고    scopus 로고
    • Putting rectal 5-aminosalicylic acid in its place: the role in distal ulcerative colitis
    • Marshall J.K., and Irvine E.J. Putting rectal 5-aminosalicylic acid in its place: the role in distal ulcerative colitis. Am J Gastroenterol 95 (2000) 1628-1636
    • (2000) Am J Gastroenterol , vol.95 , pp. 1628-1636
    • Marshall, J.K.1    Irvine, E.J.2
  • 31
    • 0021030712 scopus 로고
    • Disposition of 5-aminosalicylic acid, the active metabolite of sulphasalazine, in man
    • Fischer C., Maier K., Stumpf E., von Gaisberg U., and Klotz U. Disposition of 5-aminosalicylic acid, the active metabolite of sulphasalazine, in man. Eur J Clin Pharmacol 25 (1983) 511-515
    • (1983) Eur J Clin Pharmacol , vol.25 , pp. 511-515
    • Fischer, C.1    Maier, K.2    Stumpf, E.3    von Gaisberg, U.4    Klotz, U.5
  • 32
    • 0027198078 scopus 로고
    • Negligible excretion of 5-aminosalicylic acid in breast milk
    • Klotz U., and Harings-Kaim A. Negligible excretion of 5-aminosalicylic acid in breast milk. Lancet 342 (1993) 618-619
    • (1993) Lancet , vol.342 , pp. 618-619
    • Klotz, U.1    Harings-Kaim, A.2
  • 33
    • 0027238878 scopus 로고
    • Oroileal transit of slow release 5-aminosalicylic acid
    • Goebell H., Klotz U., Nehlsen B., and Layer P. Oroileal transit of slow release 5-aminosalicylic acid. Gut 34 (1993) 669-675
    • (1993) Gut , vol.34 , pp. 669-675
    • Goebell, H.1    Klotz, U.2    Nehlsen, B.3    Layer, P.4
  • 34
    • 0028934947 scopus 로고
    • Delivery and fate of oral mesalamine microgranules within the human small intestine
    • Layer P.H., Goebell H., Keller J., Dignass A., and Klotz U. Delivery and fate of oral mesalamine microgranules within the human small intestine. Gastroenterology 108 (1995) 1427-1433
    • (1995) Gastroenterology , vol.108 , pp. 1427-1433
    • Layer, P.H.1    Goebell, H.2    Keller, J.3    Dignass, A.4    Klotz, U.5
  • 36
    • 0033636283 scopus 로고    scopus 로고
    • Mechanisms of transport and structure-permeability relationship of sulfasalazine and its analogs in Caco-2 cell monolayers
    • Proudfoot L.E., and Yacyshyn B.R. Mechanisms of transport and structure-permeability relationship of sulfasalazine and its analogs in Caco-2 cell monolayers. Pharm Res 17 (2000) 1168-1174
    • (2000) Pharm Res , vol.17 , pp. 1168-1174
    • Proudfoot, L.E.1    Yacyshyn, B.R.2
  • 39
    • 0036325459 scopus 로고    scopus 로고
    • A review of its therapeutic use in mild-to-moderate ulcerative colitis
    • Muijsers R.B.R., Goa K.L., and Balsalazide. A review of its therapeutic use in mild-to-moderate ulcerative colitis. Drugs 62 (2002) 1689-1705
    • (2002) Drugs , vol.62 , pp. 1689-1705
    • Muijsers, R.B.R.1    Goa, K.L.2    Balsalazide3
  • 40
    • 0037253045 scopus 로고    scopus 로고
    • Systematic review: the pharmacokinetic profiles of oral mesalazine formulations and mesalazine pro-drugs used in the management of ulcerative colitis
    • Sandborn W.J., and Hanauer S.B. Systematic review: the pharmacokinetic profiles of oral mesalazine formulations and mesalazine pro-drugs used in the management of ulcerative colitis. Aliment Pharmacol Ther 17 (2003) 29-42
    • (2003) Aliment Pharmacol Ther , vol.17 , pp. 29-42
    • Sandborn, W.J.1    Hanauer, S.B.2
  • 41
    • 0023895637 scopus 로고
    • The pharmacokinetics of olsalazine sodium in healthy volunteers after a single i.v. dose and after oral doses with and without food
    • Ryde E.M., and Ahnfelt N.O. The pharmacokinetics of olsalazine sodium in healthy volunteers after a single i.v. dose and after oral doses with and without food. Eur J Clin Pharmacol 34 (1988) 481-488
    • (1988) Eur J Clin Pharmacol , vol.34 , pp. 481-488
    • Ryde, E.M.1    Ahnfelt, N.O.2
  • 42
    • 0025903764 scopus 로고
    • A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in inflammatory bowel disease
    • Wadworth A.N., Fitton A., and Olsalazine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in inflammatory bowel disease. Drugs 41 (1991) 647-664
    • (1991) Drugs , vol.41 , pp. 647-664
    • Wadworth, A.N.1    Fitton, A.2    Olsalazine3
  • 43
    • 2542575335 scopus 로고    scopus 로고
    • Withdrawal rates because of diarrhoea in Dipentum-treated patients with ulcerative colitis are low when Dipentum is taken with food and dose titrated
    • Järnerot G. Withdrawal rates because of diarrhoea in Dipentum-treated patients with ulcerative colitis are low when Dipentum is taken with food and dose titrated. Gastroenterology 110 (1996) A932
    • (1996) Gastroenterology , vol.110
    • Järnerot, G.1
  • 44
  • 45
    • 0026566566 scopus 로고
    • Randomised comparison of olsalazine and mesalazine in prevention of relapses in ulcerative colitis
    • Courtney M.G., Nunes D.P., Bergin C.F., O'Driscoll M., Trimble V., Keeling P.W.N., et al. Randomised comparison of olsalazine and mesalazine in prevention of relapses in ulcerative colitis. Lancet 339 (1992) 1279-1281
    • (1992) Lancet , vol.339 , pp. 1279-1281
    • Courtney, M.G.1    Nunes, D.P.2    Bergin, C.F.3    O'Driscoll, M.4    Trimble, V.5    Keeling, P.W.N.6
  • 46
    • 0020691917 scopus 로고
    • Absorption and excretion of a single 1-g dose of azodisal sodium in subjects with ileostomy
    • Sandberg-Gertzen H., Ryde M., and Jarnerot G. Absorption and excretion of a single 1-g dose of azodisal sodium in subjects with ileostomy. Scand J Gastroenterol 18 (1983) 107-111
    • (1983) Scand J Gastroenterol , vol.18 , pp. 107-111
    • Sandberg-Gertzen, H.1    Ryde, M.2    Jarnerot, G.3
  • 47
    • 0030003526 scopus 로고    scopus 로고
    • Systemic uptake of 5-aminosalicylic acid from olsalazine and Eudragit L coated mesalazine in patients with ulcerative colitis in remission
    • Ewe K., Becker K., and Ueberschaer B. Systemic uptake of 5-aminosalicylic acid from olsalazine and Eudragit L coated mesalazine in patients with ulcerative colitis in remission. Z Gastroenterol 34 (1996) 225-229
    • (1996) Z Gastroenterol , vol.34 , pp. 225-229
    • Ewe, K.1    Becker, K.2    Ueberschaer, B.3
  • 48
    • 0030016547 scopus 로고    scopus 로고
    • Systemic availability of 5-aminosalicylic acid: comparison of delayed release and an azo-bond preparation
    • Gionchetti P., Campieri M., Venturi A., Rizzello F., Ferretti M., Brignola C., et al. Systemic availability of 5-aminosalicylic acid: comparison of delayed release and an azo-bond preparation. Aliment Pharamcol Ther 10 (1996) 601-605
    • (1996) Aliment Pharamcol Ther , vol.10 , pp. 601-605
    • Gionchetti, P.1    Campieri, M.2    Venturi, A.3    Rizzello, F.4    Ferretti, M.5    Brignola, C.6
  • 49
    • 0029848723 scopus 로고    scopus 로고
    • Systemic absorption of 5-aminosalicylic acid in patients with inactive ulcerative colitis treated with olsalazine and mesalazine
    • Karamanolis D.G., Papatheodoridis G.V., and Xourgias V. Systemic absorption of 5-aminosalicylic acid in patients with inactive ulcerative colitis treated with olsalazine and mesalazine. Eur J Gastroenterol Hepatol 8 (1996) 1083-1088
    • (1996) Eur J Gastroenterol Hepatol , vol.8 , pp. 1083-1088
    • Karamanolis, D.G.1    Papatheodoridis, G.V.2    Xourgias, V.3
  • 50
    • 0029830881 scopus 로고    scopus 로고
    • 5-aminosalicylic acid absorption and metabolism in ulcerative colitis patients receiving maintenance sulphasalazine, olsalazine or mesalazine
    • Stretch G.L., Campbell B.J., Dwarakanath A.D., Yaqoob M., Stevenson A., Morris A.I., et al. 5-aminosalicylic acid absorption and metabolism in ulcerative colitis patients receiving maintenance sulphasalazine, olsalazine or mesalazine. Aliment Pharmacol Ther 10 (1996) 941-947
    • (1996) Aliment Pharmacol Ther , vol.10 , pp. 941-947
    • Stretch, G.L.1    Campbell, B.J.2    Dwarakanath, A.D.3    Yaqoob, M.4    Stevenson, A.5    Morris, A.I.6
  • 51
    • 0030852115 scopus 로고    scopus 로고
    • Systemic absorption of 5-aminosalicylic acid in patients with inactive ulcerative colitis treated with olsalazine and mesalazine
    • Tzivras M., Konstandinidis A., Hatzis G., Paraskeva M., Skandalis N., and Archimandritis A. Systemic absorption of 5-aminosalicylic acid in patients with inactive ulcerative colitis treated with olsalazine and mesalazine. Eur J Gastroenterol Hepatol 9 (1997) 729-730
    • (1997) Eur J Gastroenterol Hepatol , vol.9 , pp. 729-730
    • Tzivras, M.1    Konstandinidis, A.2    Hatzis, G.3    Paraskeva, M.4    Skandalis, N.5    Archimandritis, A.6
  • 52
    • 0033371888 scopus 로고    scopus 로고
    • Systemic levels of free 5-aminosalicylic acid depend on the nature of the 5-aminosalicylic acid derivative and not on disease activity or extent in patients with inflammatory bowel disease
    • Mahmud N., Weir D.G., and Kelleher D. Systemic levels of free 5-aminosalicylic acid depend on the nature of the 5-aminosalicylic acid derivative and not on disease activity or extent in patients with inflammatory bowel disease. Ir J Med Sci 168 (1999) 228-232
    • (1999) Ir J Med Sci , vol.168 , pp. 228-232
    • Mahmud, N.1    Weir, D.G.2    Kelleher, D.3
  • 53
    • 0033055298 scopus 로고    scopus 로고
    • The systemic load and efficient delivery of active 5-aminosalicylic acid in patients with ulcerative colitis on treatment with olsalazine or mesalazine
    • Støa-Birketvedt G., and Florholmen J. The systemic load and efficient delivery of active 5-aminosalicylic acid in patients with ulcerative colitis on treatment with olsalazine or mesalazine. Aliment Pharmacol Ther 13 (1999) 357-361
    • (1999) Aliment Pharmacol Ther , vol.13 , pp. 357-361
    • Støa-Birketvedt, G.1    Florholmen, J.2
  • 54
    • 0025243656 scopus 로고
    • Disposition of 5-aminosalicylic acid by olsalazine and three mesalazine preparations in patients with ulcerative colitis: comparison of intraluminal colonic concentrations, serum values, and urinary excretion
    • Laursen L.S., Stokholm M., Bukhave J., Rask-Madsen J., and Lauritsen K. Disposition of 5-aminosalicylic acid by olsalazine and three mesalazine preparations in patients with ulcerative colitis: comparison of intraluminal colonic concentrations, serum values, and urinary excretion. Gut 31 (1990) 1271-1276
    • (1990) Gut , vol.31 , pp. 1271-1276
    • Laursen, L.S.1    Stokholm, M.2    Bukhave, J.3    Rask-Madsen, J.4    Lauritsen, K.5
  • 55
    • 0032701176 scopus 로고    scopus 로고
    • Rectal and colonic mesalazine concentration in ulcerative colitis: oral vs. oral plus topical treatment
    • Frieri G., Pimpo M.T., Palumbo G.C., Onori L., Viscido A., Letella G., et al. Rectal and colonic mesalazine concentration in ulcerative colitis: oral vs. oral plus topical treatment. Aliment Pharmacol Ther 13 (1999) 1413-1417
    • (1999) Aliment Pharmacol Ther , vol.13 , pp. 1413-1417
    • Frieri, G.1    Pimpo, M.T.2    Palumbo, G.C.3    Onori, L.4    Viscido, A.5    Letella, G.6
  • 56
    • 12244289249 scopus 로고    scopus 로고
    • Oral and topical 5-aminosalicylic acid (mesalazine) in inducing and maintaining remission in mild-moderate relapse of ulcerative colitis: one year randomised multicentre trial
    • Paoluzi P., D'Albasio G., Pera A., Bianchi Porro G., Paoluzi O.A., Pica R., et al. Oral and topical 5-aminosalicylic acid (mesalazine) in inducing and maintaining remission in mild-moderate relapse of ulcerative colitis: one year randomised multicentre trial. Dig Liver Dis 34 (2002) 787-793
    • (2002) Dig Liver Dis , vol.34 , pp. 787-793
    • Paoluzi, P.1    D'Albasio, G.2    Pera, A.3    Bianchi Porro, G.4    Paoluzi, O.A.5    Pica, R.6
  • 57
    • 0038620397 scopus 로고    scopus 로고
    • Review article: oral, modified-release mesalazine formulations-proprietary versus generic
    • Forbes A., Cartwright A., Marchant S., McIntyres P., and Newton M. Review article: oral, modified-release mesalazine formulations-proprietary versus generic. Aliment Pharmacol Ther 17 (2003) 1207-1214
    • (2003) Aliment Pharmacol Ther , vol.17 , pp. 1207-1214
    • Forbes, A.1    Cartwright, A.2    Marchant, S.3    McIntyres, P.4    Newton, M.5
  • 58
    • 0033021470 scopus 로고    scopus 로고
    • Oral delayed-release mesalazine. A review of its use in ulcerative colitis and Crohn's disease
    • Prakash A., and Markham A. Oral delayed-release mesalazine. A review of its use in ulcerative colitis and Crohn's disease. Drugs 57 (1999) 383-408
    • (1999) Drugs , vol.57 , pp. 383-408
    • Prakash, A.1    Markham, A.2
  • 59
    • 0033966124 scopus 로고    scopus 로고
    • 5-Aminosalicylic acid containing drugs
    • Christensen L.A. 5-Aminosalicylic acid containing drugs. Dan Med Bull 47 (2000) 20-41
    • (2000) Dan Med Bull , vol.47 , pp. 20-41
    • Christensen, L.A.1
  • 60
    • 0034057079 scopus 로고    scopus 로고
    • Prolonged-released mesalazine. A review of its therapeutic potential in ulcerative colitis and Crohn's disease
    • Clemett D., and Markham A. Prolonged-released mesalazine. A review of its therapeutic potential in ulcerative colitis and Crohn's disease. Drugs 59 (2000) 929-956
    • (2000) Drugs , vol.59 , pp. 929-956
    • Clemett, D.1    Markham, A.2
  • 61
    • 0033823356 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of slow release mesalazine
    • De Vos M. Clinical pharmacokinetics of slow release mesalazine. Clin Pharmacokinet 39 (2000) 85-97
    • (2000) Clin Pharmacokinet , vol.39 , pp. 85-97
    • De Vos, M.1
  • 62
    • 0032523332 scopus 로고    scopus 로고
    • Release pattern of 5-aminosalicylic acid in human small intestine: importance of galenic preparation
    • Keller J., Goebell H., Klotz U., and Layer P. Release pattern of 5-aminosalicylic acid in human small intestine: importance of galenic preparation. Med Klin 93 (1998) 294-299
    • (1998) Med Klin , vol.93 , pp. 294-299
    • Keller, J.1    Goebell, H.2    Klotz, U.3    Layer, P.4
  • 63
    • 0026501185 scopus 로고
    • Prandial and diurnal effects on the absorption of orally administered enteric coated 5-aminosalicylic acid (5-ASA)
    • De Mey C., and Meineke I. Prandial and diurnal effects on the absorption of orally administered enteric coated 5-aminosalicylic acid (5-ASA). Br J Clin Pharmacol 33 (1992) 179-182
    • (1992) Br J Clin Pharmacol , vol.33 , pp. 179-182
    • De Mey, C.1    Meineke, I.2
  • 64
    • 0033983223 scopus 로고    scopus 로고
    • Gastrointestinal spread of oral prolonged-release mesalazine microgranules (Pentasa) dosed as either tablets or sachet
    • Wilding I.R., Kenyon C.-J., and Hooper G. Gastrointestinal spread of oral prolonged-release mesalazine microgranules (Pentasa) dosed as either tablets or sachet. Aliment Pharmacol Ther 14 (2000) 163-169
    • (2000) Aliment Pharmacol Ther , vol.14 , pp. 163-169
    • Wilding, I.R.1    Kenyon, C.-J.2    Hooper, G.3
  • 65
    • 0037514407 scopus 로고    scopus 로고
    • Combined scintigraphic and pharmacokinetic investigation of enteric-coated mesalazine micropellets in healthy subjects
    • Wilding I.R., Behrens C., Tardif S.J., Wray H., Bias P., and Albrecht W. Combined scintigraphic and pharmacokinetic investigation of enteric-coated mesalazine micropellets in healthy subjects. Aliment Pharmacol Ther 17 (2003) 1153-1162
    • (2003) Aliment Pharmacol Ther , vol.17 , pp. 1153-1162
    • Wilding, I.R.1    Behrens, C.2    Tardif, S.J.3    Wray, H.4    Bias, P.5    Albrecht, W.6
  • 68
    • 10744222222 scopus 로고    scopus 로고
    • The optimal dose of 5-aminosalicylic acid in active ulcerative colitis: a dose-finding study with newly developed mesalamine
    • Kruis W., Bar-Meir S., Feher J., Mickisch O., Mritz H., Fazcyk M., et al. The optimal dose of 5-aminosalicylic acid in active ulcerative colitis: a dose-finding study with newly developed mesalamine. Clin Gastroenterol Hepatol 1 (2003) 36-43
    • (2003) Clin Gastroenterol Hepatol , vol.1 , pp. 36-43
    • Kruis, W.1    Bar-Meir, S.2    Feher, J.3    Mickisch, O.4    Mritz, H.5    Fazcyk, M.6
  • 69
    • 0034776410 scopus 로고    scopus 로고
    • Sulphasalazine and 5-aminosalicylic acid in long-term treatment of ulcerative colitis: report on tolerance and side-effects
    • Di Paolo M.C., Paoluzi O.A., Pica R., Iacopini F., Crispino P., Rivera M., et al. Sulphasalazine and 5-aminosalicylic acid in long-term treatment of ulcerative colitis: report on tolerance and side-effects. Dig Liver Dis 33 (2001) 563-569
    • (2001) Dig Liver Dis , vol.33 , pp. 563-569
    • Di Paolo, M.C.1    Paoluzi, O.A.2    Pica, R.3    Iacopini, F.4    Crispino, P.5    Rivera, M.6
  • 70
    • 0842265246 scopus 로고    scopus 로고
    • Systematic review: short-term adverse effects of 5-aminosalicylic agents in the treatment of ulcerative colitis
    • Loftus Jr. E.V., Kane S.V., and Bjorkman D. Systematic review: short-term adverse effects of 5-aminosalicylic agents in the treatment of ulcerative colitis. Aliment Pharmacol Ther 19 (2004) 179-189
    • (2004) Aliment Pharmacol Ther , vol.19 , pp. 179-189
    • Loftus Jr., E.V.1    Kane, S.V.2    Bjorkman, D.3
  • 71
    • 2942587176 scopus 로고    scopus 로고
    • 5-Aminosalicylic acid and the risk of renal disease: a large British epidemiologic study
    • Van Staa T.P., Travis S., Leutkens H.G.M., and Logan R.F. 5-Aminosalicylic acid and the risk of renal disease: a large British epidemiologic study. Gastroenterology 126 (2004) 1733-1739
    • (2004) Gastroenterology , vol.126 , pp. 1733-1739
    • Van Staa, T.P.1    Travis, S.2    Leutkens, H.G.M.3    Logan, R.F.4
  • 72
    • 4844225502 scopus 로고    scopus 로고
    • Review article: aminosalicylate in inflammatory bowel disease
    • Hanauer S.B. Review article: aminosalicylate in inflammatory bowel disease. Aliment Pharmacol Ther 20 Suppl. 14 (2004) 60-65
    • (2004) Aliment Pharmacol Ther , vol.20 , Issue.SUPPL. 14 , pp. 60-65
    • Hanauer, S.B.1
  • 73
    • 14944378189 scopus 로고    scopus 로고
    • Nitric oxide-releasing mesalamine: potential utility for treatment of inflammatory bowel disease
    • Wallace J.L. Nitric oxide-releasing mesalamine: potential utility for treatment of inflammatory bowel disease. Dig Liver Dis 35 Suppl. 2 (2003) S-35-S-40
    • (2003) Dig Liver Dis , vol.35 , Issue.SUPPL. 2
    • Wallace, J.L.1
  • 74
    • 0344466539 scopus 로고    scopus 로고
    • The intestinal anti-inflammatory activity of UR-12746S on reactivated experimental colitis is mediated through downregulation of cytokine production
    • Gálvez J., Garrido M., Rodriguez-Cabezas M.E., Ramis I., de Medina F.S., Merlos M., et al. The intestinal anti-inflammatory activity of UR-12746S on reactivated experimental colitis is mediated through downregulation of cytokine production. Inflamm Bowel Dis 9 (2003) 363-371
    • (2003) Inflamm Bowel Dis , vol.9 , pp. 363-371
    • Gálvez, J.1    Garrido, M.2    Rodriguez-Cabezas, M.E.3    Ramis, I.4    de Medina, F.S.5    Merlos, M.6
  • 75
  • 76
    • 0032877923 scopus 로고    scopus 로고
    • Novel oral specific drug delivery systems for pharmacotherapy of peptide and nonpeptide drugs
    • Reddy S.M., Sinha V.R., and Reddy D.S. Novel oral specific drug delivery systems for pharmacotherapy of peptide and nonpeptide drugs. Drugs Today 35 (1999) 537-580
    • (1999) Drugs Today , vol.35 , pp. 537-580
    • Reddy, S.M.1    Sinha, V.R.2    Reddy, D.S.3
  • 77
    • 0038725720 scopus 로고    scopus 로고
    • Pharmaceutical approaches to colon targeted drug delivery systems
    • Chourasia M.K., and Jain S.K. Pharmaceutical approaches to colon targeted drug delivery systems. J Pharm Sci 6 (2003) 33-66
    • (2003) J Pharm Sci , vol.6 , pp. 33-66
    • Chourasia, M.K.1    Jain, S.K.2


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