Photic- and pattern-induced seizures: A review for the epilepsy foundation of america working group

Epilepsia

Volumn 46, Issue 9, 2005, Pages 1426-1441

  Fisher, Robert S ^a   Harding, Graham ^b   Erba, Giuseppe ^c   Barkley, Gregory L ^d   Wilkins, Arnold ^e  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^b ASTON UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^d HENRY FORD HOSPITAL   (United States)

^e UNIVERSITY OF ESSEX   (United Kingdom)

Author keywords

Epilepsy; Photosensitivity; Reflex seizures; Review; Seizures

Indexed keywords

ADOLESCENT; ADULT; AUDIOVISUAL EQUIPMENT; CHILD; CONSENSUS; DISEASE PREDISPOSITION; ELECTROENCEPHALOGRAM; EPILEPSY; HEALTH CARE ORGANIZATION; HUMAN; JAPAN; LUMINANCE; PHOTOSENSITIVITY; PHOTOSTIMULATION; PREVALENCE; PRIORITY JOURNAL; REFLEX SEIZURE; REVIEW; RISK REDUCTION; SEIZURE; TELEVISION; UNITED KINGDOM; VISUAL DISCRIMINATION; ART; COMPUTER TERMINAL; CONFERENCE PAPER; CONSENSUS DEVELOPMENT; LIGHT; PATTERN RECOGNITION; PHYSIOLOGY; REFLEX EPILEPSY; UNITED STATES;

CARTOONS; COMPUTER TERMINALS; EPILEPSY, REFLEX; LIGHT; PATTERN RECOGNITION, VISUAL; PHOTIC STIMULATION; TELEVISION; UNITED STATES;

EID: 26944468742     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2005.31405.x     Document Type: Review

References (156)

1. Harding GF Wilkins AJ Erba G, et al. Photic- and pattern-induced seizures: expert consensus of the Epilepsy Foundation of America Working Group. Epilepsia 2005 46 : 1423 25.
2. Newmark ME Penry JK. Photosensitivity and epilepsy: a review. New York : Raven Press, 1979.
3. Harding GFA Jeavons PM. Photosensitive epilepsy. London : MacKeith Press, 1994.
4. Gowers WR. Epilepsy and other chronic convulsive diseases: their causes, symptoms and treatment. New York : Wood, 1885.
5. Radovici MM Misirliou VL Gluckman M. Epilepsie reflexe provoquee par excitations optiques des rayons solaires. Rev Neurol 1932 1 : 1305 8.
6. Livingston S. Comments on the study of light-induced epilepsy in children. Am J Dis Child 1952 83 : 409.
7. Binnie CD Wilkins AJ. Visually induced seizures not caused by flicker (intermittent light stimulation). Adv Neurol 1998 75 : 123 38.
8. Guerrini R Bonanni P Parmeggiani L, et al. Induction of partial seizures by visual stimulation: clinical and electroencephalographic features and evoked potential studies. Adv Neurol 1998 75 : 159 78.
9. Jeavons PM Harding GF. Photosensitive epilepsy: a review of the literature and a study of 460 patients. In : Clinics in developmental medicine. No. 56. London : William Heineman Medical Books, 1975 : 1 121.
10. Kasteleijn-Nolst Trenité DGA. Photosensitivity in epilepsy: electrophysiological and clinical correlates. Acta Neurol Scand Suppl 1989 125 : 3 149.
11. Kasteleijn-Nolst Trenité DGA. Reflex seizures induced by intermittent light stimulation. Adv Neurol 1998 75 : 99 121.
12. Parra J Kalitzin SN Lopes da Silva FH. Photosensitivity and visually induced seizures: review. Curr Opin Neurol 2005 18 : 155 9.
13. Verrotti A Trotta D Salladini C, et al. Photosensitivity and epilepsy. J Child Neurol 2004 19 : 571 8.
14. Wilkins AJ. Visual stress. Oxford : Oxford University Press, 1995.
15. Zifkin BG Kasteleijn-Nolst Trenité D. Reflex epilepsy and reflex seizures of the visual system: a clinical review. Epileptic Disord 2000 2 : 129 36.
16. Gastaut H Regis H Bostem F. Attacks provoked by television, and their mechanism Epilepsia 1962 3 : 438 45.
17. Bickford RG Daly D Keith HM. Convulsive effects of light stimulation in children. Am J Dis Child 1953 8 : 170 83.
18. Harding GF Harding PF. Televised material and photosensitive epilepsy. Epilepsia 1999 40 ( suppl 4 65 9.
19. Kasteleijn-Nolst Trenité DGA Binnie CD Harding GF, et al. Photic stimulation: standardization of screening methods. Epilepsia 1999 40 ( suppl 4 75 9.
20. Rubboli G Parra J Seri S, et al. EEG diagnostic procedures and special investigations in the assessment of photosensitivity. Epilepsia 2004 45 ( suppl 1 35 9.
21. Nagarajan L Kulkarni A Palumbo-Clark L, et al. Photoparoxysmal responses in children: their characteristics and clinical correlates. Pediatr Neurol 2003 29 : 222 6.
22. Waltz S Christen HJ Doose H. The different patterns of the photo paroxysmal response: a genetic study. Electroencephalogr Clin Neurophysiol 1992 83 : 138 45.
23. Maheshwari MC Jeavons PM. The clinical significance of occipital spikes as a sole response to intermittent photic stimulation. Electroencephalogr Clin Neurophysiol 1975 39 : 93 5.
24. Jayakar P Chiappa KH. Clinical correlations of photoparoxysmal responses. Electroencephalogr Clin Neurophysiol 1990 75 : 251 4.
25. Reilly EL Peters JF. Relationship of some varieties of electroencephalographic photosensitivity to clinical convulsive disorders. Neurology 1973 23 : 1050 7.
26. Puglia JF Brenner RP Soso MJ. Relationship between prolonged and self-limited photoparoxysmal responses and seizure incidence: study and review. J Clin Neurophysiol 1992 9 : 137 44.
27. Kasteleijn-Nolst Trenité DGA Binnie CD Meinardi H. Photosensitive patients: symptoms and signs during intermittent photic stimulation and their relation to seizures in daily life. J Neurol Neurosurg Psychiatry 1987 50 : 1546 9.
28. Jabbari B Russo MB Russo ML Electroencephalogram of asymptomatic adult subjects. Clin Neurophysiol 2000 111 : 102 5.
29. Agathonikou A Koutroumanidis M Panayiotopoulos CP. Fixation-off-sensitive epilepsy with absences and absence status: video-EEG documentation. Neurology 1997 48 : 231 4.
30. deBittencourt PRM. Photosensitivity: the magnitude of the problem. Epilepsia 2004 45 ( suppl 1 1 5.
31. Erba G. Preventing seizures from "Pocket Monsters": a way to control reflex epilepsy. Neurology 2001 57 : 1747 8.
32. Kasteleijn-Nolst Trenité DGA Binnie CD Harding GFA, et al. Medical technology assessment: photic stimulation: standardization of screening methods. Neurophysiol Clin 1999 29 : 318 24.
33. Shiraishi H Fujiwara T Inoue Y, et al. Photosensitivity in relation to epileptic syndromes: a survey from an epilepsy center in Japan. Epilepsia 2001 42 : 393 7.
34. Appleton R Beirne M Acomb B. Photosensitivity in juvenile myoclonic epilepsy. Seizure 2000 9 : 108 11.
35. Holden EW Thanh Nguyen H Grossman E, et al. Estimating prevalence, incidence, and disease-related mortality for patients with epilepsy in managed care organizations. Epilepsia 2005 46 : 311 9.
36. Fisher RS van Emde Boas W Blume W, et al. Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE). Epilepsia 2005 46 : 470 2.
37. Gregory RP Oates T Merry RTG. Electroencephalogram epileptiform abnormalities and candidates for aircrew training. Electroencephalogr Clin Neurophysiol 1993 86 : 75 7.
38. Trojaborg W. EEG abnormalities in 5,893 jet pilot applicants registered in a 20-year period. Clin Electroencephalogr 1992 23 : 72 8.
39. Jeavons PM Bishop A Harding GF. The prognosis of photosensitivity. Epilepsia 1986 27 : 569 75.
40. Wadlington WB Rightly HD Jr.. Light-induced seizures. J Pediatr 1965 66 : 300 12.
41. Danesi MA. Seasonal variations in the incidence of photoparoxysmal response to stimulation among photosensitive epileptic patients: evidence from repeated EEG recordings. J Neurol Neurosurg Psychiatry 1988 51 : 875 7.
42. Steinkruger M. Photosensitive epilepsy. J Neurosurg Nurs 1985 17 : 355 61.
43. Doose H Waltz S. Photosensitivity-genetics and clinical significance. Neuropediatrics 1993 24 : 249 55.
44. Eeg-Olofsson O Petersen I Sellden U. The development of the electroencephalogram in normal children from the age of 1 through 15 years: paroxysmal activity. Neuropadiatrie 1971 2 : 375 404.
45. Petersen I Eeg-Olofsson O. The development of the electroencephalogram in normal children from the age of 1 through 15 years: non-paroxysmal activity. Neuropadiatrie 1971 2 : 247 304.
46. Harding GF. TV can be bad for your health. Nat Med 1998 4 : 265 7.
47. Ishida S Yamashita Y Matsuishi T, et al. Photosensitive seizures provoked while viewing "Pocket Monsters," a made-for-television animation program in Japan. Epilepsia 1998 39 : 1340 4.
48. Takahashi T Tsukahara Y. Pocket Monster incident and low luminance visual stimuli: special reference to deep red flicker stimulation. Acta Paediatr Jpn 1998 40 : 631 7.
49. Takada H Aso K Watanabe K, et al. Epileptic seizures induced by animated cartoon, "Pocket Monster." Epilepsia 1999 40 : 997 1002.
50. Iinuma K. TV-animation induced seizures. Acta Paediatr Jpn 1998 40 : 624 5.
51. Quirk JA Fish DR Smith SJ, et al. First seizures associated with playing electronic screen games: a community-based study in Great Britain. Ann Neurol 1995 37 : 733 7.
52. Aziz H Francis P Ali SM, et al. Epilepsy and photosensitivity. J Pak Med Assoc 1989 39 : 212 4.
53. Takahashi T. Photoconvulsive response and disposition. Folia Psychiatr Neurol Jpn 1976 30 : 349 56.
54. Quirk JA Fish DR Smith SJ, et al. Incidence of photosensitive epilepsy: a prospective national study. Electroencephalogr Clin Neurophysiol 1995 95 : 260 7.
55. Harding GF Edson A Jeavons PM. Persistence of photosensitivity. Epilepsia 1997 38 : 663 9.
56. Verrotti A Trotta D Salladini C, et al. Photosensitivity and epilepsy: a follow-up study. Dev Med Child Neurol 2004 46 : 347 51.
57. Scott DF Elian M. The effects on the EEG of intermittent photic stimulation in patients over 30 years of age. Clin Electroencephalogr 1981 12 : 21 3.
58. Binnie CD. Simple reflex epilepsies. In : Engel J Jr. Pedley TA, eds. A comprehensive textbook of epilepsy. Philadelphia : Lippincott-Raven, 1997 : 2507 14.
59. De Graaf AS Van Wyk Kotze TJ, et al. Photoparoxysmal responses in the electroencephalograms of some ethnic groups of the Cape Peninsula. Electroencephalogr Clin Neurophysiol 1980 50 : 275 81.
60. Obeid T Daif AK Waheed G, et al. Photosensitive epilepsies and photoconvulsive responses in Arabs. Epilepsia 1991 32 : 77 81.
61. Victor M Brausch C. The role of abstinence in the genesis of alcoholic epilepsy. Epilepsia 1967 8 : 1 20.
62. Wolf P Goosses R. Relation of photosensitivity to epileptic syndromes. J Neurol Neurosurg Psychiatry 1986 49 : 1386 91.
63. Hennessy MJ Binnie CD. Photogenic partial seizures. Epilepsia 2000 41 : 59 64.
64. Gilliam FG Chiappa KH. Significance of spontaneous epileptiform abnormalities associated with a photoparoxysmal response. Neurology 1995 45 : 453 6.
65. Hormes JT Mellinger JF Klass DW. Testing for electroencephalographic activation with video games in patients with light sensitivity. Am J EEG Technol 1995 35 : 37 45.
66. Binnie CD Kasteleijn-Nolst Trenité DG De Korte R. Photosensitivity as a model for acute antiepileptic drug studies. Electroencephalogr Clin Neurophysiol 1986 63 : 35 41.
67. De Keyser J Michotte A Ebinger G. Television induced seizures in alcoholics. Br Med J 1984 289 : 1191 2.
68. Ferrie CD De Marco P Grunewald RA, et al. Video game induced seizures. J Neurol Neurosurg Psychiatry 1994 57 : 925 31.
69. Wilkins A Lindsay J. Common forms of reflex epilepsy: physiological mechanisms and techniques for treatment. Recent Adv Epilepsy 1985 2 : 239 71.
70. Mayr N Wimberger D Pichler H, et al. Influence of television on photosensitive epileptics. Eur Neurol 1987 27 : 201 8.
71. Binnie CD Findlay J Wilkins AJ. Mechanisms of epileptogenesis in photosensitive epilepsy implied by the effects of moving patterns. Electroencephalogr Clin Neurophysiol 1985 61 : 1 6.
72. Chatrian GE Lettich E Miller LH, et al. Pattern-sensitive epilepsy, I: an electrographic study of its mechanisms. Epilepsia 1970 11 : 125 49.
73. Radhakrishnan K St Louis EK Johnson JA, et al. Pattern-sensitive epilepsy: electroclinical characteristics, natural history, and delineation of the epileptic syndrome. Epilepsia 2005 46 : 48 58.
74. Wilkins AJ Darby CE Binnie CD. Neurophysiological aspects of pattern-sensitive epilepsy. Brain 1979 102 : 1 25.
75. Guy NTM Teillet MA Schuler B, et al. Pattern of electroencephalographic activity during light induced seizures in genetic epileptic chickens and brain chimeras. Neurosci Lett 1992 145 : 55 8.
76. Naquet R Menini C Riche D, et al. Photic epilepsy problems raised in man and animals. Ital J Neurol Sci 1987 8 : 437 47.
77. Ostrach LH Crabtree JW Campbell BG, et al. Effects of bicuculline-induced epileptiform activity on development of receptive field properties in striate cortex and lateral geniculate nucleus of the rabbit. Brain Res 1984 317 : 113 23.
78. Wilkins AJ Bonanni P Porciatti V, et al. Physiology of human photosensitivity. Epilepsia 2004 45 ( suppl 1 7 13.
79. Meldrum BS Wilkins AJ. Photosensitive epilepsy: integration of pharmacological and psychophysical evidence. In : Schwatzkroin P Wheal H, eds. Electrophysiology of epilepsy. London : Academic Press, 1984 : 51 77.
80. Wilkins AJ Binnie C Darby CE, et al. Inferences regarding the visual precipitation of seizures, eye-strain and headaches. In : Avoli M Gloor P Kostopoulos G, et al., eds. Generalized epilepsy: neurobiological approaches. Birkhauser : Boston, 1990 : 314 26.
81. Hubel DH Wiesel TN. Receptive fields of single neurones in the cat's striate cortex. J Physiol 1959 148 : 574 91.
82. Zeki S. The visual association cortex. Curr Opin Neurobiol 1993 3 : 155 9.
83. Porciatti V Bonanni P Fiorentini A, et al. Lack of cortical contrast gain control in human photosensitive epilepsy. Nat Neurosci 2000 3 : 259 63.
84. Quesney LF Andermann F Gloor P. Dopaminergic mechanism in generalized photosensitive epilepsy. Neurology 1981 31 : 1542 4.
85. Fischer-Williams M Ponset M Riche D, et al. light induced epilepsy in the baboon Papio papio: cortical and depth recordings. Electroencephalogr Clin Neurophysiol 1968 25 : 557 69.
86. Matsuoka H. Seizure generation mechanisms in reflex epilepsy. Jpn J Psychiatry Neurol 1990 44 : 317 20.
87. Takasaka Y Takamatsu K Nakagawara M. Anterior-posterior relationships of EEG in photosensitive subjects: coherence and cross-phase-spectral analysis. Jpn J Psychiatry Neurol 1989 43 : 651 63.
88. Parra J Kalitzin SN Iriarte J, et al. Gamma-band phase clustering and photosensitivity: is there an underlying mechanism common to photosensitive epilepsy and visual perception¿ Brain 2003 126 : 1164 72.
89. Inoue Y Fukao K Araki T, et al. Photosensitive and nonphotosensitive electronic screen game-induced seizures. Epilepsia 1999 40 ( suppl 4 8 16.
90. Chiappa KH Hill RA Huang-Hellinger F, et al. Photosensitive epilepsy studied by functional magnetic resonance imaging and magnetic resonance spectroscopy. Epilepsia 1999 40 ( suppl 4 3 7.
91. 15O]-water PET study on photosensitive epilepsy. Epilepsia 1999 40 ( suppl 4 17 22.
92. Wilkins AJ Binnie CD Darby CE. Visually-induced seizures. Prog Neurobiol 1980 15 : 85 117.
93. Benbadis SR Gerson WA Harvey JH, et al. Photosensitive temporal lobe epilepsy. Neurology 1996 46 : 1540 2.
94. Isnard J Guenot M Fischer C, et al. Stereoelectroencephalographic (SEEG) study of light-induced mesiotemporal epileptic seizures. Epilepsia 1998 39 : 1098 103.
95. Topalkara K Alarcon G Binnie CD. Effects of flash frequency and repetition of intermittent photic stimulation on photoparoxysmal responses. Seizure 1998 7 : 249 55.
96. Honda Y. Photo epilepsy evoked by square-wave pulses: report of the case studied by changing stimulus intensity and duration. J Pediatr Ophthalmol 1977 14 : 309 15.
97. Hiachikawa Y Yamamoto J Furuya E, et al. Photosensitive epilepsy: relationships between the visual evoked responses and the epileptic formed discharges induced by intermittent photo stimulation. Electroencephalogr Clin Neurophysiol 1967 23 : 320 34.
98. Chatrian GE Lettich E Miller LH, et al. Pattern-sensitive epilepsy, II: clinical changes, tests of responsiveness and motor output, alterations of evoked potentials and therapeutic measures. Epilepsia 1970 11 : 151 62.
99. Binnie CD Kasteleijn-Nolst Trenité DG de Korte R, et al. Visual display units and risk of seizures Letter Lancet 1985 1 : 991.
100. Leijten FS Dekker E Spekreijse H, et al. Light diffusion in photosensitive epilepsy. Electroencephalogr Clin Neurophysiol 1998 106 : 387 91.
101. Anyanwu E Watson NA. Visually-evoked pattern and photomyoclonic responses in video game and television epilepsy: case reports. Acta Physiol Pharmacol Ther Latinoam 1996 46 : 177 84.
102. Anyanwu E. Mental imagery of photic stimulation provokes paroxysmal EEG activity in a photosensitive patient who self-induces seizures. Ital J Neurol Sci 1997 18 : 93 100.
103. Rafal RD Laxer KD Janowsky JS. Seizures triggered by blinking in non-photosensitive patients. J Neurol Neurosurg Psychiatry 1986 49 : 445 7.
104. Binnie CD de Korte RA Wisman T. Fluorescent lighting and epilepsy. Epilepsia 1979 20 : 725 7.
105. Takahashi T Tsukahara Y. Influence of color on the photoconvulsive response. Electroencephalogr Clin Neurophysiol 1976 41 : 124 36.
106. Tobimatsu S Zhang YM Tomoda Y, et al. Chromatic sensitive epilepsy: a variant of photosensitive epilepsy. Ann Neurol 1999 45 : 790 3.
107. Binnie CD Estevez O Kasteleijn-Nolst Trenité DG, et al. Colour in photosensitive epilepsy. Electroencephalogr Clin Neurophysiol 1984 58 : 387 91.
108. Takahashi Y Fujiwara T Yagi K, et al. Wavelength dependence of photoparoxysmal responses in photosensitive patients with epilepsy. Epilepsia 1999 40 ( suppl 4 23 7.
109. Wilkins AJ Baker A Amin D, et al. Treatment of photosensitive epilepsy using coloured glasses. Seizure 1999 8 : 444 9.
110. Stefansson SB Darby CE Wilkins AJ, et al. Television epilepsy and pattern sensitivity. Br Med J 1977 2 : 88 90.
111. Brinciotti M Matricardi M Pelliccia A, et al. Pattern sensitivity and photosensitivity in epileptic children with visually induced seizures. Epilepsia 1994 35 : 842 9.
112. Anyanwu E. Evaluation of the laboratory and environmental factors that induce seizures in photosensitive epilepsy. Acta Neurol Belg 1999 99 : 126 32.
113. Funatsuka M Fujita M Shirakawa S, et al. Study on photo-pattern sensitivity in patients with electronic screen game-induced seizures (ESGS): effects of spatial resolution, brightness, and pattern movement. Epilepsia 2001 42 : 1185 97.
114. Wilkins AJ Emmett J Harding G. Characterising the flashing and pattern images that precipitate seizures, and optimising guidelines to prevent them. Paper presented at the Photosensitivity and Seizures Workshop. Alexandria, Va : Epilepsy Foundation of America, 2004.
115. Aso K Watanabe K Negoro T, et al. Photosensitive epilepsy in children. Seizure 1994 3 : 67 71.
116. Darby CE de Korte RA Binnie CD, et al. The self-induction of epileptic seizures by eye closure. Epilepsia 1980 21 : 31 41.
117. Tassinari CA Rubboli G Rizzi R, et al. Self-induction of visually-induced seizures. Adv Neurol 1998 75 : 179 92.
118. Spector S Cull C Goldstein LH. Seizure precipitants and perceived self-control of seizures in adults with poorly-controlled epilepsy. Epilepsy Res 2000 38 : 207 16.
119. Badinand-Hubert N Bureau M Hirsch E, et al. Epilepsies and video games: results of a multicentric study. Electroencephalogr Clin Neurophysiol 1998 107 : 422 7.
120. Fylan F Harding GFA. The effect of television frame rate on EEG abnormalities in photosensitive and pattern-sensitive epilepsy. Epilepsia 1997 38 : 1124 31.
121. Ricci S Vigevano F Manfredi M Kasteleijn-Nolst Trenité DG. Epilepsy provoked by television and video games: safety of 100-Hz screens. Neurology 1998 50 : 790 3.
122. Enoki H Akiyama T Hattori J, et al. Photosensitive fits elicited by TV animation: an electroencephalographic study. Acta Paediatr Jpn 1998 40 : 626 30.
123. Rushton DN. "Space invader" epilepsy. Lancet 1981 1 : 501.
124. Jeavons PM Barton ME Bishop A. Seizures and hand-held space invaders. Lancet 1981 2 : 758.
125. Daneshmend TK Campbell MJ. Dark warrior epilepsy Br Med J 1982 284 : 1751 2.
126. Dahlquist NR Mellinger JF Klass DW. Hazard of video games in patients with light-sensitive epilepsy. JAMA 1983 249 : 776 7.
127. Christie T. Death after an attack precipitated by playing Nintendo game. Sun 1993 21 : 5. Q5
128. Takahashi T. Photosensitive epilepsy. Tokyo : Igaku-Shoin, 2002.
129. Bureau M Hirsch E Vigevano F. Epilepsy and videogames. Epilepsia 2004 45 ( suppl 1 1 3.
130. Harding GF Jeavons PM Edson AS. Video material and epilepsy. Epilepsia 1994 35 : 1208 16.
131. Kasteleijn-Nolst Trenité DGA da Silva AM Ricci S, et al. Video-game epilepsy: a European study. Epilepsia 1999 40 ( suppl 4 70 4.
132. Maeda Y Kurokawa T Sakamoto K, et al. Electroclinical study of video-game epilepsy. Dev Med Child Neurol 1990 32 : 493 500.
133. Graf WD Chatrian GE Glass ST, et al. Video game-related seizures: a report on 10 patients and a review of the literature. Pediatrics 1994 93 : 551 6.
134. Takahashi Y Shigematsu H Kubota H, et al. Nonphotosensitive video game-induced partial seizures. Epilepsia 1995 36 : 837 41.
135. Pellouchoud E Smith ME, et al. Mental effort-related EEG modulation during video-game play: comparison between juvenile subjects with epilepsy and normal control subjects. Epilepsia 1999 40 ( suppl 4 38 43.
136. William DG Gian-Amelio C Stefan TG, et al. Video game-related seizures: a report on two patients and a review of the literature. Pediatrics 1994 93 : 551 6.
137. Ricci S Vigevano F. The effect of video-game software in video-game epilepsy. Epilepsia 1999 40 ( suppl 4 31 7.
138. Millett CJ Fish DR Thompson PJ, et al. Seizures during video-game play and other common leisure pursuits in known epilepsy patients without visual sensitivity. Epilepsia 1999 40 ( suppl 4 59 64.
139. Millett CJ Fish DR Thompson PJ. A survey of epilepsy-patient perceptions of video-game material/electronic screens and other factors as seizure precipitants. Seizure 1997 6 : 457 9.
140. Harding GF Takahashi T. Regulations; what next¿ Epilepsia 2004 45 ( suppl 1 46 7.
141. Nomura M Takahashi T Kamijo K, et al. A new adaptive temporal filter: application to photosensitive epilepsy patients. Psychiatry Clin Neurosci 2000 54 : 685 90.
142. Parra J Kalitzin SN Stroink H, et al. Removal of epileptogenic sequences from video material: the role of color. Neurology 2005 64 : 787 91.
143. Capovilla G Beccaria F Romeo A, et al. Effectiveness of a particular blue lens on photoparoxysmal response in photosensitive epileptic patients. Ital J Neurol Sci 1999 20 : 161 6.
144. Kepecs MR Boro A Haut S, et al. A novel nonpharmacologic treatment for photosensitive epilepsy: a report of three patients tested with blue cross-polarized glasses. Epilepsia 2004 45 : 1158 62.
145. Takahashi T Tsukahara Y. Usefulness of blue sunglasses in photosensitive epilepsy. Epilepsia 1992 33 : 517 21.
146. Takahashi Y Sato T Goto K, et al. Optical filters inhibiting television-induced photosensitive seizures. Neurology 2001 57 : 1767 73.
147. Covanis A Stodieck SR Wilkins AJ. Treatment of photosensitivity. Epilepsia 2004 45 ( suppl 1 40 5.
148. Rimmer EM Milligan NM Richens A. A comparison of the acute effect of single doses of vigabatrin and sodium valproate on photosensitivity in epileptic patients. Epilepsy Res 1987 1 : 339 46.
149. Harding GFA Herrick CE Jeavons PM. A controlled study of the effect of sodium valproate on photosensitive epilepsy and its prognosis. Epilepsia 1978 19 : 555 65.
150. Moller A Jensen LH Skrumsager B, et al. Inhibition of photosensitive seizures in man by the beta-carboline, ZK 95962, a selective benzodiazepine receptor agonist. Epilepsy Res 1990 5 : 155 9.
151. Saenz-Lope E Herranz-Tanarro FJ Masdeu JC, et al. Familial photosensitive epilepsy: effectiveness of clonazepam. Clin Electroencephalogr 1984 15 : 47 52.
152. Clemens B. Dopamine agonist treatment of self-induced pattern-sensitive epilepsy: a case report. Epilepsy Res 1988 2 : 340 3.
153. Shuper A Vining EP. Photosensitive complex partial seizures aggravated by phenytoin. Pediatr Neurol 1991 7 : 471 2.
154. Kasteleijn-Nolst Trenité DGA Marescaux C Stodieck S, et al. Photosensitive epilepsy: a model to study the effects of antiepileptic drugs: evaluation of the piracetam analogue, levetiracetam. Epilepsy Res 1996 25 : 225 30.
155. Binnie CD Harding GFA Richens A, et al. Video games and epileptic seizures: a consensus statement. Seizure 1994 3 : 245 6.
156. Takahashi Y Fujiwara T. Effectiveness of broadcasting guidelines for photosensitive seizure prevention. Neurology 2004 62 : 990 3.