Alteration of cytochromep-450 and glutathione S-transferase activity in normal and malignant human stomach

Journal of Toxicology and Environmental Health - Part A

Volumn 68, Issue 19, 2005, Pages 1611-1620

  Hyung, Sik Kim ^a   Seung, Jun Kwack ^b   Byung, Mu Lee ^b  

^a Pusan National University   (South Korea)

^b Sungkyunkwan University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; GLUTATHIONE TRANSFERASE;

ADULT; AGED; ARTICLE; CANCER RISK; CIGARETTE SMOKING; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SEX DIFFERENCE; STOMACH ADENOCARCINOMA; STOMACH CARCINOGENESIS; ADENOCARCINOMA; ADOLESCENT; CASE CONTROL STUDY; CHILD; ENZYMOLOGY; ISOLATION AND PURIFICATION; METABOLISM; MIDDLE AGED; RISK FACTOR; SMOKING; STOMACH; STOMACH TUMOR;

HELICOBACTER; HELICOBACTER PYLORI;

ADENOCARCINOMA; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; CHILD; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; GLUTATHIONE TRANSFERASE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; MIDDLE AGED; RISK FACTORS; SMOKING; STOMACH; STOMACH NEOPLASMS;

EID: 26944434376     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390500182867     Document Type: Article

References (40)

1. Baik, S. C., Youn, H. S., Chung, M. H., Lee, W. K., Cho, M. J., Ko, G. H., Park, C. K., Kasai, H., and Rhee, K. H. 1996. Increased oxidative DNA damage in Helicobacter pylori-infected human gastric mucosa. Cancer Res 56:1279-1282.
2. Carlson, G. P. 1997. Effects of inducers and inhibitors on the microsomal metabolism of styrene to styrene oxide in mice. J. Toxicol. Environ. Health. 51:477-488.
3. Correa, P. 1995. Helicobacter pylori and gastric carcinogenesis. Am. J. Surg. Pathol. 19:S37-S43.
4. Davies, G. R., Simmonds, N. J., Stevens, T. R. J., Sheaff, M. T., Banatvala, N., Laurenson, I. F., Blake, D. R., and Rampton, D. S. 1994. Helicobacter pylori stimulates antral mucosal reactive oxygen metabolite production in vivo. Gut 35:179-185.
5. Drake, I. M., Davies, M. J., Mapstone, N. P., Dixon, M. F., Schorah, C. J., White, K. L. M., Chalmers, D. M., and Axon, A. T. R. 1996. Ascorbic acid may protect against human gastric cancer by scavenging mucosal oxygen radicals. Carcinogenesis 17:559-562.
6. Forman, D. 1991. The etiology of gastric cancer. IARC Sci. Publ. 105:22-32.
7. Gao, C. M., Takezaki, T., Wu, J. Z., Li, Z. Y., Liu, Y. T., Li, S. P., Ding, J. H., Su, P., Hu, X., Xu, T. L., Sugimura, H., and Tajima, K. 2002. Glutathione-S-transferases M1 (GSTM1) and GSTT1 genotype, smoking, consumption of alcohol and tea and risk of esophageal and stomach cancers: A case-control study of a high-incidence area in Jiangsu Province, China. Cancer Lett. 188:95-102.
8. Griffin, G. D., Egan, B. Z., Lee, N. E., and Burtis, C. A. 1986. Induction of mixed-function oxidase activity in mouse lymphoid tissues by polycyclic aromatic hydrocarbons. J. Toxicol. Environ. Health. 19:185-194.
9. Habig, W. H., Pabst, M. J., and Jakoby, W. B. 1974. Glutathione-S- transferase: The first step in mercapturic acid formation. J. Biol. Chem. 249:7130-7139.
10. Hall, C. N., Badawi, A. F., O'Connor, P. J., and Saffhill, R. 1991. The detection of alkylation damage in the DNA of human gastrointestinal tissues. Br. J. Cancer 64:59-63.
11. Hoffmann, D., and Hoffmann, I. 1997. The changing cigarette, 1950-1995. J. Toxicol. Environ. Health 50:307-364.
12. Hu, X., Benson, P. J., Srivastava, S. K., Xia, H., Bleicher, R. J., Zaren, H. A., Awasthi, S., Awasthi, Y. C., and Singh, S. V. 1997. Induction of glutathione S-transferase pi as a bioassay for the evaluation of potency of inhibitors of benzo(a)pyrene-induced cancer in a murine model. Int. J. Cancer. 73:897-902.
13. IARC 1973. Certain polycyclic aromatic hydrocarbons and heterocyclic compounds. IARC Monogr. Eval. Carcinogen. Risk Chem. Man. 3:91-136.
14. Inoue, M., Tajima, K., Hirose, K., Kuroishi, T., Gao, C. M., and Kitoh, T. 1994. Life-style and subsite of gastric cancer - Joint effect of smoking and drinking habits. Int. J. Cancer. 56:494-499.
15. Jakoby, W. B. 1978. The glutathione transferase: A group of multifunctional detoxification protein. Adv. Enzymol. 46:383-414.
16. Kato, S., Onda, M., Matsukura, N., Matsuda, N., Tokunaga, A., and Matsushita, H. 1999. Genotype-phenotype relationship for cytochrome p450s (CYP) in gastric normal and tumor tissues. Proc. Am. Assoc. Cancer Res. 40:244.
17. Kim, D., and Guengerich, F. P. 2005. Cytochrome p450 activation of arylamines and heterocyclic amines. Annu. Rev. Pharmacol. Toxicol. 45:27-49.
18. Koizumi, Y., Tsubono, Y., Nakaya, N., Kuriyama, S., Shibuya, D., Matsuoka, H., and Tsuji, I. 2004. Cigarette smoking and the risk of gastric cancer: A pooled analysis of two prospective studies in Japan. Int. J. Cancer. 112:1049-1055.
19. Lee, B. M., Jang, J. J., and Kim, H. S. 1998a. Benzo[a]pyrene diol-epoxide-I-DNA and oxidative DNA adducts associated with gastric adenocarcinoma. Cancer Lett. 125:61-68.
20. Lee, B. M., Jang, J. J., Kim, J. S., You, Y. C., Chun, S. A., Kim, H. S., Han, H. M., Ahn, M. Y., and Byun, S. H. 1998b. Association of Helicobacter pylori infection with gastric adenocarcinoma. Jpn. J. Cancer Res. 89:597-603.
21. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:265-275.
22. Mirvish, S. S. 1977. N-Nitroso compounds: their chemical and in vivo formation and possible importance as environmental carcinogens. J. Toxicol. Environ. Health. 2:1267-1277.
23. Mohammadzadeh, G. S., Nasseri Moghadam, S., Rasaee, M. J., Zaree, A. B., Mahmoodzadeh, H., and Allameh, A. 2003. Measurement of glutathione S-transferase and its class-pi in plasma and tissue biopsies obtained after laparoscopy and endoscopy from subjects with esophagus and gastric cancer. Clin. Biochem. 36:283-288.
24. Nebert, D. W., McKinnon, R. A., and Puga, A. 1996. Human drug-metabolizing enzyme polymorphisms: Effects on risk of toxicity and cancer. DNA Cell Biol. 15:273-280.
25. Nomura, A., Grove, J. S., Stemmermann, G. M., and Severson, R. K. 1996. A prospective study of stomach cancer and its relation to diet, cigarettes, and alcohol consumption. Cancer Res. 50:627-631.
26. Oijen, A. H., Verhulst, M. L., Roelofs, H. M., Peters, W. H., de Boer, W. A., and Jansen, J. B. 2001. Eradication of Helicobacter pylori restores glutathione S-transferase activity and glutathione levels in antral mucosa. Jpn. J. Cancer Res. 92:1329-1334.
27. Omura, T., and Sato, R. 1964. The carbon monoxide-binding pigment of liver microsomes. J. Biol. Chem. 239:2379-2385.
28. Peters, W. H., Roelofs, H. M., Hectors, M.. P., Nagengast, F. M., and Jansen, J. B. 1993. Glutathione and glutathione S-transferases in Barrett's epithelium. Br. J. Cancer. 67:1413-1417.
29. Risch, H. A., Jain, M., Choi, N. W., Fodor, J. G., Pfeiffer, C. J., Howe, G. R., Harrison, L. W., Carib, K. J., and Miller, A. B. 1985. Dietary factors and incidence of cancer of the stomach. Am. J. Epidemiol. 122:947-959.
30. Schipper, D. I., Wagenmans, M. J., Peters, W. H., van Haelst, U., Wobbes, T., Verhofstad, A. A., and Wagener, D. J. 1996. Glutathione S-transferases in gastric carcinomas and in adjacent normal gastric epithelium: Immunohistochemical and biochemical analyses. Anticancer Res. 16:3721-3724.
31. Sharma, R., Haque, A. K., Awasthi, S., Singh, S. V., Piper, J. T., and Awasthi, Y. C. 1997. Differential carcinogenicity of benzo[a]pyrene in male and female CD-1 mouse lung. J. Toxicol. Environ. Health 52:45-62.
32. Shirin, H., Pinto, J. T., Liu, L. U., Merzianu, M., Sordillo, E. M., and Moss, S. F. 2001. Helicobacter pylori decreases gastric mucosal glutathione. Cancer Lett. 164:127-133.
33. Suzuki, S., Muroishi, Y., Nakanishi, I, and Oda, Y. 2004. Relationship between genetic polymorphisms of drug-metabolizing enzyme (CYP1A1, CYP2E1, GSTM1, AND NAT2), drinking habits, historical subtypes, and p53 gene point mutations in Japanese patients with gastric cancer. J. Gastroenterol. 39:220-230.
34. Thapliyal, R., Deshpande, S. S., and Maru, G. B. 2002. Mechanism(s) of turmeric-mediated protective effects against benzo(a)pyrene-derived DNA adducts. Cancer Lett. 175:79-88.
35. Tsugane, S., Tei, Y., Takabashi, T., Watanabe, S., and Sugano, K. 1994. Salty food intake and risk of Helicobacter pylori infection. Jpn. J. Cancer Res. 85:474-478.
36. Verhulst, M. L., Hopman, W. P., Peters, W. H., and Jansen, J. B. 2000a. Effects of Helicobacter pylori infection on endocrine and exocrine mucosal functions in the upper gastrointestinal tract. Scand. J. Gastroenterol. Suppl. 232:21-31.
37. Verhulst, M. L., van Oijen, A. H., Roelofs, H. M., Peters, W. H., and Jansen, J. B. 2000b. Antral glutathione concentration and glutathione S-transferase activity in patients with and without Helicobacter pylori. Dig. Dis. Sci. 45:629-632.
38. Wiencke, J. K., Kelsey, K. T., Lamela, R. A., and Toscano, W. A., Jr. 1990. Human glutathione S-transferase deficiency as a marker of susceptibility to epoxide-induced cytogenetic damage. Cancer Res. 50:1585-1590.
39. Wu, M. S., Chen, C. J., Lin, M. T., Wang, H. P., Shun, C. T., Sheu, J. C., and Lin, J. T. 2002. Genetic polymorphisms of cytochrome p450 2E1, glutathione S-transferase M1 and T1, and susceptibility to gastric carcinoma in Taiwan. Int. J. Colorectal Dis. 17:338-343.
40. Wong, H. L., Murphy, S. E., and Hecht, S. S. 2005. Cytochrome P450 2A-catalyzed metabolic activation of structurally similar carcinogenic nitrosamines: N′-Nitrosonornicotine enantiomers, N-nitrosopiperidine, and N-nitrosopyrrolidine. Chem. Res. Toxicol. 18:61-69.