Cloning of the gene encoding a protective Mycobacterium tuberculosis secreted protein detected in vivo during the initial phases of the infectious process

Journal of Immunology

Volumn 175, Issue 8, 2005, Pages 5298-5305

  Mukherjee, Sandeep ^a   Kashino, Suely S ^b   Zhang, Yanni ^c   Daifalla, Nada ^a   Rodrigues Jr , Virmondes ^d   Reed, Steven G ^a,e   Campos Neto, Antonio ^b  

^a INFECTIOUS DISEASE RESEARCH INSTITUTE   (United States)

^b FORSYTH INSTITUTE   (United States)

^c GLAXOSMITHKLINE   (United States)

^d Medical School of Triangulo Mineiro   (Brazil)

^e UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; IMMUNOLOGICAL ADJUVANT; MYCOBACTERIUM ANTIGEN; MYCOBACTERIUM VACCINE; PHOSPHORYL LIPID A; PLASMID DNA; QS 21; RECOMBINANT ANTIGEN; TUBERCULIN; U2 ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN RECOGNITION; ARTICLE; BACTERIAL GROWTH; CONTROLLED STUDY; DISEASE ACTIVITY; ESCHERICHIA COLI; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; LYMPHOID CELL; MASS SPECTROMETRY; MOLECULAR CLONING; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN SECRETION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEQUENCE HOMOLOGY; T LYMPHOCYTE; TH1 CELL; TUBERCULIN TEST; TUBERCULOSIS; VACCINE PRODUCTION;

EID: 26844530018     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.175.8.5298     Document Type: Article

References (37)

1. Dye, C., S. Scheele, P. Dolin, V. Pathania, and M. C. Raviglione. 1999. Consensus statement. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO Global Surveillance and Monitoring Project. J. Am. Med. Assoc. 282: 677-686.
2. World Health Organization. 1994. The current global situation of the HIV/AIDS pandemic. Wkly. Epidemiol. Rec. 69: 191-192.
3. Raviglione, M. C., D. E. Snider, Jr., and A. Kochi. 1995. Global epidemiology of tuberculosis: morbidity and mortality of a worldwide epidemic. J. Am. Med. Assoc. 273: 220-226.
4. Netto, E. M., C. Dye, and M. C. Raviglione. 1999. Progress in global tuberculosis control 1995-1996, with emphasis on 22 high-incidence countries: Global Monitoring and Surveillance Project. Int. J. Tuberc. Lung Dis. 3: 310-320.
5. Colditz, G. A., T. F. Brewer, C. S. Berkey, M. E. Wilson, E. Burdick, H. V. Fineberg, and F. Mosteller. 1994. Efficacy of BCG vaccine in the prevention of tuberculosis: meta-analysis of the published literature. J. Am. Med. Assoc. 271: 698-702.
6. Dolin, P. J., M. C. Raviglione, and A. Kochi. 1994. Global tuberculosis incidence and mortality during 1990-2000. Bull W. H. O. 72: 213-220.
7. Ginsberg, A. M. 1998. The tuberculosis epidemic: scientific challenges and opportunities. Public Health Rep. 113: 128-136.
8. Jouanguy, E., F. Altare, S. Lamhamedi, P. Revy, J. F. Emile, M. Newport, M. Levin, S. Blanche, E. Seboun, A. Fischer, and J. L. Casanova. 1996. Interferon-γ-receptor deficiency in an infant with fatal bacille Calmette-Guerin infection. N. Engl. J. Med. 335: 1956-1961.
9. Newport, M. J., C. M. Huxley, S. Huston, C. M. Hawrylowicz, B. A. Oostra, R. Williamson, and M. Levin. 1996. A mutation in the interferon-γ- receptor gene and susceptibility to mycobacterial infection. N. Engl. J. Med. 335: 1941-1949.
10. Andersen, P. 1994. Effective vaccination of mice against Mycobacterium tuberculosis infection with a soluble mixture of secreted mycobacterial proteins. Infect. Immun. 62: 2536-2544.
11. Horwitz, M. A., B. E. Lee, B. J. Dillon, and G. Harth. 1995. Protective immunity against tuberculosis by vaccination with major extracellular proteins of Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. USA 92: 1530-1534.
12. Hubbard, R. D., C. M. Flory, and F. M. Collins. 1992. Immunization of mice with mycobacterial culture filtrate proteins. Clin. Exp. Immunol. 87: 94-98.
13. Pal, P. G., and M. A. Horwitz. 1992. Immunization with extracellular proteins of Mycobacterium tuberculosis induces cell-mediated immune responses and substantial protective immunity in a guinea pig model of pulmonary tuberculosis. Infect. Immun. 60: 4781-4792.
14. Roberts, A. D., M. G. Sonnenberg, D. J. Ordway, S. K. Furney, P. J. Brennan, J. T. Belisle, and I. M. Orme. 1995. Characteristics of protective immunity engendered by vaccination of mice with purified culture filtrate antigens. Immunology 85: 502-508.
15. Boesen, H., B. N. Jensen, T. Wilcke, and P. Andersen. 1995. Human T-cell responses to secreted antigen fractions of Mycobacterium tuberculosis. Infect. Immun. 63: 1491-1497.
16. Coler, R. N., Y. A. W. Skeiky, T. Vedivick, T. Bement, P. Ovendale, A. Campos-Neto, M. R. Alderson, and S. G. Reed. 1998. Molecular cloning and immunologic reactivity of a novel low molecular mass antigen of Mycobacterium tuberculosis. J. Immunol. 161: 2356-2364.
17. Young, D. B., S. H. Kaufmann, P. W. Hermans, and J. E. Thole. 1992. Mycobacterial protein antigens: a compilation. Mol. Microbiol. 6: 133-145.
18. Brandt, L., M. Elhay, I. Rosenkrands, E. B. Lindblad, and P. Andersen. 2000. ESAT-6 subunit vaccination against Mycobacterium tuberculosis. Infect. Immun. 68: 791-795.
19. Coler, R. N., A. Campos-Neto, P. Ovendale, F. H. Day, S. P. Fling, L. Zhu, N. Serbina, J. L. Flynn, S. G. Reed, and M. R. Alderson. 2001. Vaccination with the T cell antigen Mtb 8.4 protects against challenge with Mycobacterium tuberculosis. J. Immunol. 166: 6227-6235.
20. Skeiky, Y. A., P. J. Ovendale, S. Jen, M. R. Alderson, D. C. Dillon, S. Smith, C. B. Wilson, I. M. Orme, S. G. Reed, and A. Campos-Neto. 2000. T cell expression cloning of a Mycobacterium tuberculosis gene encoding a protective antigen associated with the early control of infection. J. Immunol. 165: 7140-7149.
21. Weinrich, O. A., L. A. van Pinxteren, O. L. Meng, R. P. Birk, and P. Andersen. 2001. Protection of mice with a tuberculosis subunit vaccine based on a fusion protein of antigen 85b and esat-6. Infect. Immun. 69: 2773-2778.
22. Wiker, H. G., and M. Harboe. 1992. The antigen 85 complex: a major secretion product of Mycobacterium tuberculosis. Microbiol. Rev. 56: 648-661.
23. + T cells. J. Exp. Med. 191: 551-560.
24. Sonnenberg, M. G., and J. T. Belisle. 1997. Definition of Mycobacterium tuberculosis culture filtrate proteins by two-dimensional polyacrylamide gel electrophoresis, N-terminal amino acid sequencing, and electrospray mass spectrometry. Infect. Immun. 65: 4515-4524.
25. Gygi, S. P., G. L. Corthals, Y. Zhang, Y. Rochon, and R. Aebersold. 2000. Evaluation of two-dimensional gel electrophoresis-based proteome analysis technology. Proc. Natl. Acad. Sci. USA 97: 9390-9395.
26. Yates, J. R., III, J. K. Eng, A. L. McCormack, and D. Schieltz. 1995. Method to correlate tandem mass spectra of modified peptides to amino acid sequences in the protein database. Anal. Chem. 67: 1426-1436.
27. Mukherjee, S., N. Daifalla, C. Liu, and A. Campos-Neto. 2003. Alternative approach to express Mycobacterium tuberculosis proteins in Escherichia coli. Bio-Techniques 35: 34-36.
28. Coler, R. N., Y. A. Skeiky, P. J. Ovendale, T. S. Vedvick, L. Gervassi, J. Guderian, S. Jen, S. G. Reed, and A. Campos-Neto. 2000. Cloning of a Mycobacterium tuberculosis gene encoding a purified protein derivative protein that elicits strong tuberculosis-specific delayed-type hypersensitivity. J. Infect. Dis. 182: 224-233.
29. Reed, S. G., R. N. Coler, and A. Campos-Neto. 2003. Development of a leishmaniasis vaccine: the importance of MPL. Expert Rev. Vaccines 2: 239-252.
30. Anacker, R. L., W. R. Barclay, W. Brehmer, C. L. Larson, and E. Ribi. 1967. Duration of immunity to tuberculosis in mice vaccinated intravenously with oil-treated cell walls of Mycobacterium bovis strain BCG. J. Immunol. 98: 1265-1273.
31. Ribi, E., C. L. Larson, W. Wicht, R. Ist, and G. Goode. 1965. Resistance to experimental tuberculosis stimulated by fractions from attenuated tubercle bacilli. Proc. Soc. Exp. Biol. Med. 118: 926-933.
32. Weiss, D. W. 1959. Vaccination against tuberculosis with nonliving vaccines. I. The problem and its historical background. Am. Rev. Respir. Dis. 80: 340-358.
33. Chambers, M. A., D. C. Wright, J. Brisker, A. Williams, G. Hatch, D. Gavier-Widen, G. Hall, P. D. Marsh, and H. R. Glyn. 2004. A single dose of killed Mycobacterium bovis BCG in a novel class of adjuvant (Novasome) protects guinea pigs from lethal tuberculosis. Vaccine 22: 1063-1071.
34. Haile, M., U. Schroder, B. Hamasur, A. Pawlowski, T. Jaxmar, G. Kallenius, and S. B. Svenson. 2004. Immunization with heat-killed Mycobacterium bovis bacille Calmette-Guerin (BCG) in Eurocine L3 adjuvant protects against tuberculosis. Vaccine 22: 1498-1508.
35. Agger, E. M., K. Weldingh, A. W. Olsen, I. Rosenkrands, and P. Andersen. 2002. Specific acquired resistance in mice immunized with killed mycobacteria. Scand. J. Immunol. 56: 443-447.
36. Orme, I. M. 1987. The kinetics of emergence and loss of mediator T lymphocytes acquired in response to infection with Mycobacterium tuberculosis. J. Immunol. 138: 293-298.
37. Orme, I. M. 1988. Characteristics and specificity of acquired immunologic memory to Mycobacterium tuberculosis infection. J. Immunol. 140: 3589-3593.