Synthesis, cytotoxicity, and structure-activity relationships of new oxaliplatin derivatives

Monatshefte fur Chemie

Volumn 136, Issue 5, 2005, Pages 693-700

  Galanski, Markus ^a   Yasemi, Afshin ^a   Jakupec, Michael A ^a   Keyserlingk, Nikolai Graf V ^b   Keppler, Bernhard K ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b Faustus Forschungs Co T   (Germany)

Author keywords

Antitumor agent; Bioinorganic chemistry; Coordination chemistry; Drug research; Metal complexes

Indexed keywords

(4 PHENYLCYCLOHEXANE 1,2 DIAMINE)OXALATOPLATINUM; (4 PROPYLCYCLOHEXANE 1,2 DIAMINE)OXALATOPLATINUM; [4 (1,1 DIMETHYLETHYL)CYCLOHEXANE 1,2 DIAMINE]OXALATOPLATINUM; DICHLORO(4 PHENYLCYCLOHEXANE 1,2 DIAMINE)PLATINUM; DICHLORO(4 PROPYLCYCLOHEXANE 1,2 DIAMINE)PLATINUM; DICHLORO[4 (1,1 DIMETHYLETHYL)CYCLOHEXANE 1,2 DIAMINE]PLATINUM; OXALIPLATIN; PLATINUM DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LEUKEMIA CELL; LIPOPHILICITY; OVARY CANCER; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

EID: 18544389361     PISSN: 00269247     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00706-004-0241-3     Document Type: Article

References (18)

1. Rosenberg B (1978) Interdiscip Sci Rev 3: 134
2. Lippert B (ed) (1999) Cisplatin: Chemistry and Biochemistry of a Leading Anticancer Drug. Verlag Helvetica Chimica Acta, Zürich, and Wiley-VCH, Weinheim
3. O'Dwyer PJ, Stevenson JP, Johnson SW (2000) Drugs 59: 19
4. O'Dwyer PJ, Stevenson JP, Johnson SW (1999) Clinical status of cisplatin, carboplatin, and other platinum-based antitumor drugs. In: Lippert B (ed) Cisplatin: Chemistry and Biochemistry of a Leading Anticancer Drug. Verlag Helvetica Chimica Acta, Zürich, and Wiley-VCH, Weinheim, p 31
5. Jakupec MA, Galanski M, Keppler BK (2003) Rev Physiol Biochem Pharmacol 146: 1
6. Kidani Y, Noji M, Tashiro T (1980) Gann 71: 637
7. Cvitkovic E, Bekradda M (1999) Semin Oncol 26: 647
8. O'Dwyer PJ, Johnson SW (2003) Semin Oncol 30: 78
9. Graham J, Muhsin M, Kirkpatrick P (2004) Nat Rev Drug Discov 3: 11
10. Reedijk J (1996) Chem Commun 801
11. Jamieson ER, Lippard SJ (1999) Chem Rev 99: 2467
12. Scheeff ED, Briggs JM, Howell SB (1999) Mol Pharmacol 56: 633
13. Spingler B, Whittington DA, Lippard SJ (2001) Inorg Chem 40: 5596
14. Malina J, Kasparkova J, Natile G, Brabec V (2002) Chemistry and Biology 9: 629
15. Graham MA, Lockwood GF, Greenslade D, Brienza S, Bayssas M, Gamelin E (2000) Clin Cancer Res 6: 1205
16. Galanski M, Yasemi A, Slaby S, Jakupec MA, Arion VB, Rausch M, Nazarov AA, Keppler BK (2004) Eur J Med Chem 39: 707
17. Snyder BB, Lin H (1998) Synth Commun 28: 1913
18. Corey EJ, Nicolaou KC, Balanson RD, Machida Y (1975) Synthesis 9: 590