The structure and synthetic capabilities of a catalytic peptide formed by substrate-directed mechanism - Implications to prebiotic catalysis

Origins of Life and Evolution of the Biosphere

Volumn 35, Issue 4, 2005, Pages 369-382

  Fleminger, Gideon ^a   Yaron, Tal ^a   Eisenstein, Miriam ^b   Bar Nun, Akiva ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Anhydrous synthesis; Catalytic peptides; Iron; Prebiotic catalysis

Indexed keywords

2 NITROPHENYLGALACTOSIDE; 2-NITROPHENYLGALACTOSIDE; 4 NITROPHENYLGALACTOSIDE; CYSTEINE; DIPEPTIDE; IRON; MICROSPHERE;

CATALYSIS; ORIGIN OF LIFE; PEPTIDE;

ARTICLE; ASTRONOMY; BIOGENESIS; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; KINETICS; SYNTHESIS;

BIOGENESIS; CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTEINE; DIPEPTIDES; EVOLUTION, CHEMICAL; HYDROLYSIS; IRON; KINETICS; MICROSPHERES; MODELS, MOLECULAR; NITROPHENYLGALACTOSIDES;

EID: 26844485468     PISSN: 01696149     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11084-005-4084-7     Document Type: Article

References (21)

1. Bar-Nun, A., Kochavi, E. and Bar-Nun, S.: 1994, An Assemblage of Free Amino Acids as a Possible Prebiotic Enzyme, J. Mol. Evol. 39, 116-122.
2. Chu, B. C. and Orgel, L. E.: 1999, Peptide-Formation on Cysteine-Containing Peptide Scaffolds, Orig. Life Evol. Biosph. 29, 441-449.
3. Deiana, S., Gessa, C., Solinas, V., Piu, P. and Seeber, J.: 1989, Complexing and Redox Properties of the System D-galacturonic acid-iron(III), J. Inorg. Biochem. 35, 107-113.
4. Escandar, G. M., Gandolfo, F. H. and Sala, E. F.: 1990, Complex Formation Between Aldonic and Uronic Acids and Ferric Ion in Aqueous Solution. An. Asoc. Quim. Argent. 78, 37-48.
5. Fersht, A. R.: 1971, Acyl-Transfer Reactions of Amides and Esters with Alcohols and Thiols. Reference System for the Serine and Cysteine Proteinases. Nitrogen Protonation of Amides and Amide-Imidate Equilibriums, J. Amer. Chem. Soc. 93, 3504-3515.
6. Fischer, G. and Aumuller, T.: 2003, Regulation of Peptide Bond cis/trans Isomerization by Enzyme Catalysis and its Implication in Physiological Processes, Rev. Physiol. Biochem. Pharmacol. 148, 105-150.
7. Geetha, K., Raghavan, M. S. S., Kulshreshtha, S. K., Sasikala, R. and Rao, C. P.: 1995, Transition - Metal Saccharide Chemistry - Synthesis, Spectroscopy, Electrochemistry and Magnetic-Susceptibility Studies of Iron(III) Complexes of Monosaccharides and Disaccharides, Carbohydrate Res. 271, 163-175.
8. Gyurcsik, B. and Nagy, L.: 2000, Carbohydrates as Ligands: Coordination Equilibria and Structure of the Metal Complexes, Coordination Chem. Rev. 203, 81-149.
9. Harris, L. F., Sullivan, M. R. and Hatfield, D. L.: 1999, Directed Molecular Evolution, Orig. Life Evol. Biosph. 29, 425-435.
10. Klibanov, A. M.: 2001, Improving Enzymes by Using them in Organic Solvents, Nature 409, 241-246.
11. Kochavi, E., Bar-Nun, A. and Fleminger, G.: 1997, Substrate-Directed Formation of Small Biocatalysts Under Prebiotic Conditions, J. Mol. Evol. 45, 342-351.
12. Lahav, N. and Nir, S.: 1997, Emergence of Template-and-Sequence-Directed (TSD) Syntheses: I. A Bio-Geochemical Model, Orig. Life Evol. Biosph. 27, 377-395.
13. Or'o, J. and Stephane-Sherwoon, E.: 1976, Abiotic Origin of Biopolymers, Orig. Life 7, 37-47.
14. Perricaudet, M. and Pullman, A.: 1973, An Abinitio Quantum-Mechanical Investigation on the Rotational Isomerism in Amides and Esters, Int J. Pept. Protein Res. 5, 99-107.
15. Rao, C. P., Geetha, K., Raghavan, M. S. S., Sreedhara, A., Tokunaga, K., Yamaguchi, T., Jadhav, V., Ganesh, K. N., Krishnamoorthy, T., Ramaiah, K. V. A. and Bhattacharyya, R. K.: 2000, Transition Metal Saccharide Chemistry and Biology: Syntheses, Characterization, Solution Stability and Putative Bio-Relevant Studies of Iron-Saccharide Complexes, Inorg. Chim. Acta 297, 373-382.
16. De-Rose, V. J.: 2002. Two Decades of RNA Catalysis, Chem. Biol. 9, 961-969.
17. Saetia, S., Liedl, K. R., Eder, A. H. and Rode, B. M.: 1993, Evaporation Cycle Experiments - A Simulation of Salt-Induced Peptide Synthesis Under Possible Prebiotic Conditions, Orig. Life Evol. Biosph. 23, 167-176.
18. Schwendinger, M. G. and Rode, B. M.: 1992, Investigations on the Mechanism of the Salt-Induced Peptide Formation, Orig. Life Evol. Biosph. 22, 349-359.
19. Szathmary, E.: 1999, The Origin of the Genetic Code: Amino Acids as Cofactors in an RNA World, Trends Genet. 15, 223-229.
20. Steinman, G., Kenyon, D. H. and Calvin, M.: 1965, Dehydration Condensation in Aqueous Solution, Nature 206, 707-708.
21. Riddles, P. W., Blakeley, R. L. and Zerner, B.: 1983, Reassessment of Ellman's Reagent, Methods Enzymol. 91, 49-60.