A peptide from the first fibronectin domain of NCAM acts as an inverse agonist and stimulates FGF receptor activation, neurite outgrowth and survival

Journal of Neurochemistry

Volumn 95, Issue 2, 2005, Pages 570-583

  Anderson, Alexandra A ^a   Kendal, Claire E ^a   Garcia Maya, Mitla ^a   Kenny, Anna V ^a   Morris Triggs, Samantha A ^a   Wu, Teresa ^a   Reynolds, Richard ^a   Hohenester, Erhard ^a   Saffell, Jane L ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Bioactive peptide; Cell survival; Fibroblast growth factor receptor; Fibronectin type III domain; Neural cell adhesion molecule; Neurite outgrowth

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR; FIBRONECTIN; FRM PEPTIDE; NERVE CELL ADHESION MOLECULE; PEPTIDE; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

AGONIST; ANIMAL CELL; ARTICLE; CELL ASSAY; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEVELOPMENT; FIBROBLAST GROWTH FACTOR RECEPTOR ACTIVATION MOTIF; IN VITRO STUDY; INVERSE AGONIST; LEARNING; MEMORY; NERVE FIBER GROWTH; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

3T3 CELLS; ANIMALS; ANTIBODIES, BLOCKING; ANTIMETABOLITES; BIOTRANSFORMATION; BROMODEOXYURIDINE; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CYCLIZATION; FIBRONECTINS; MICE; MODELS, MOLECULAR; NEURAL CELL ADHESION MOLECULES; NEURITES; OLIGODENDROGLIA; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; RATS; RECEPTORS, FIBROBLAST GROWTH FACTOR;

EID: 26844476866     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2005.03417.x     Document Type: Article

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