Cardioprotective role of the mitochondrial ATP-binding cassette protein 1

Circulation Research

Volumn 97, Issue 8, 2005, Pages 740-742

  Ardehali, Hossein ^a   O'Rourke, Brian ^b   Marbán, Eduardo ^b,c  

^a NORTHWESTERN UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Adenovirus; Apoptosis; ATP binding cassette proteins; Mitochondria; RNA interference

Indexed keywords

ABC TRANSPORTER A1; ADENINE NUCLEOTIDE TRANSLOCASE; CARRIER PROTEIN; MESSENGER RNA; PHOSPHATE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; SUCCINATE DEHYDROGENASE; TETRAMETHYLRHODAMINE ETHYL ESTER; TRYPAN BLUE;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; FLOW CYTOMETRY; HEART PROTECTION; IMMUNOPRECIPITATION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MOLECULAR BIOLOGY; MOLECULAR MODEL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INDUCTION; RAT; RNA INTERFERENCE; STATISTICAL SIGNIFICANCE;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CYTOPROTECTION; HUMANS; HYDROGEN PEROXIDE; MEMBRANE POTENTIALS; MITOCHONDRIA, HEART; MYOCYTES, CARDIAC; OXIDATIVE STRESS; POTASSIUM CHANNELS; RATS; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 26844431925     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000186277.12336.11     Document Type: Article

References (10)

1. Klein I, Sarkadi B, Varadi A. An inventory of the human ABC proteins. Biochim Biophys Acta. 1999;1461:237-262.
2. Higgins CF, Linton KJ. ABC transporter: an introduction and overview. In: Holland IB, Cole SPG, Kuchler K, Higgins CF, eds. ABC Proteins. San Diego, Calif: Academic Press; 2003: ix-xvii.
3. Hogue DL, Liu L, Ling V. Identification and characterization of a mammalian mitochondrial ATP-binding cassette membrane protein. J Mol Biol. 1999;285:379-389.
4. Chloupkova M, LeBard LS, Koeller DM. MDL1 is a high copy suppressor of ATM1: evidence for a role in resistance to oxidative stress. J Mol Biol. 2003;331:155-165.
5. Young L, Leonhard K, Tatsuta T, Trowsdale J, Langer T. Role of the ABC transporter Mdl1 in peptide export from mitochondria. Science. 2001;291:2135-2138.
6. Paucek P, Mironova G, Mahdi F, Beavis AD, Woldegiorgis G, Garlid KD. Reconstitution and partial purification of the glibenclamide-sensitive, ATP-dependent K + channel from rat liver and beef heart mitochondria. J Biol Chem. 1992;267:26062-26069.
7. Liu Y, Sato T, O'Rourke B, Marbán E. Mitochondrial ATP-dependent potassium channels: novel effectors of cardioprotection? Circulation. 1998;97:2463-2469.
8. Ardehali H, Chen Z, Ko Y, Mejia-Alvarez R, Marbán E. Multiprotein complex containing succinate dehydrogenase confers mitochondrial ATP-sensitive K+ channel activity. Proc Natl Acad Sci U S A. 2004;101:11880-11885.
9. Teshima Y, Akao M, Jones SP, Marbán E. Uncoupling protein-2 overexpression inhibits mitochondrial death pathway in cardiomyocytes. Circ Res. 2003;93:192-200.
10. Akao M, O'Rourke B, Teshima Y, Seharaseyon J, Marbán E. Mechanistically-distinct steps in the mitochondrial death pathway triggered by oxidative stress in cardiac myocytes. Circ Res. 2003;92:186-194.