Tolerance to the procholinergic action of the D1 receptor full agonist dihydrexidine

Psychopharmacology

Volumn 182, Issue 3, 2005, Pages 393-399

  Wade, Mark R ^a   Nomikos, George G ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Acetylcholine release; Cognition; D1; Dementia; Dopamine receptor; Hippocampus; In vivo microdialysis; Tolerance

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; DIHYDREXIDINE; DOPAMINE 1 RECEPTOR BLOCKING AGENT; DOPAMINE 1 RECEPTOR STIMULATING AGENT;

ACETYLCHOLINE RELEASE; ANIMAL EXPERIMENT; ARTICLE; BRAIN DEPTH STIMULATION; BRAIN LEVEL; CHOLINERGIC ACTIVITY; COGNITION; CONTROLLED STUDY; DOSE RESPONSE; HIPPOCAMPUS; MALE; MICRODIALYSIS; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; RAT; RECEPTOR INTRINSIC ACTIVITY;

ACETYLCHOLINE; ANIMALS; DOPAMINE AGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; HIPPOCAMPUS; MALE; PHENANTHRIDINES; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D1;

EID: 26844431580     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-005-0106-4     Document Type: Article

References (42)

1. Acquas E, Di Chiara G (1999) Dopamine D(1) receptor-mediated control of striatal acetylcholine release by endogenous dopamine. Eur J Pharmacol 383:121-127
2. Acquas E, Fibiger HC (1998) Dopaminergic regulation of striatal acetylcholine release: the critical role of acetylcholinesterase inhibition. J Neurochem 70:1088-1093
3. Acquas E, Day JC, Fibiger HC (1994) The potent and selective dopamine D1 receptor agonist A-77636 increases cortical and hippocampal acetylcholine release in the rat. Eur J Pharmacol 260:85-87
4. Acquas E, Wilson C, Fibiger HC (1997) Nonstriatal dopamine D1 receptors regulate striatal acetylcholine release in vivo. J Pharmacol Exp Ther 281:360-368
5. Arnsten AF, Cai JX, Murphy BL, Goldman-Rakic PS (1994) Dopamine D1 receptor mechanisms in the cognitive performance of young adult and aged monkeys. Psychopharmacology 116:143-151
6. Asin KE, Wirtshafter D (1993) Effects of repeated dopamine D1 receptor stimulation on rotation and c-fos expression. Eur J Pharmacol 235:167-168
7. Asin KE, Bednarz L, Nikkel A, Perner R (1995) Rotation and striatal c-fos expression after repeated, daily treatment with selective dopamine receptor agonists and levodopa. J Pharmacol Exp Ther 273:1483-1490
8. Asin KE, Domino EF, Nikkel A, Shiosaki K (1997) The selective dopamine D1 receptor agonist A-86929 maintains efficacy with repeated treatment in rodent and primate models of Parkinson's disease. J Pharmacol Exp Ther 281:454-459
9. Brewster WK, Nichols DE, Riggs RM, Mottola DM, Lovenberg TW, Lewis MH, Mailman RB (1990) trans-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a] phenanthridine: a highly potent selective dopamine D1 full agonist. J Med Chem 33:1756-1764
10. Castner SA, Williams GV, Goldman-Rakic PS (2000) Reversal of antipsychotic-induced working memory deficits by short-term dopamine D1 receptor stimulation. Science 287:2020-2022
11. Console S, Baronio P, Guidi G, Di Chiara G (1996) Role of the parafascicular thalamic nucleus and N-methyl-D-aspartate transmission in the D1-dependent control of in vivo acetylcholine release in rat striatum. Neuroscience 71:157-165
12. Damsma G, Tham CS, Robertson GS, Fibiger HC (1990) Dopamine D1 receptor stimulation increases striatal acetylcholine release in the rat. Eur J Pharmacol 186:335-338
13. Darney KJ Jr, Lewis MH, Brewster WK, Nichols DE, Mailman RB (1991) Behavioral effects in the rat of dihydrexidine, a high-potency, full-efficacy D1 dopamine receptor agonist. Neuropsychopharmacology 5:187-195
14. Day J, Fibiger HC (1993) Dopaminergic regulation of cortical acetylcholine release: effects of dopamine receptor agonists. Neuroscience 54:643-648
15. Day JC, Fibiger HC (1994) Dopaminergic regulation of septohippocampal cholinergic neurons. J Neurochem 63:2086-2092
16. DeBoer P, Abercrombie ED (1996) Physiological release of striatal acetylcholine in vivo: modulation by D1 and D2 dopamine receptor subtypes. J Pharmacol Exp Ther 277:775-783
17. Engber TM, Marin C, Susel Z, Chase TN (1993) Differential effects of chronic dopamine D1 and D2 receptor agonists on rotational behavior and dopamine receptor binding. Eur J Pharmacol 236:385-393
18. Goldman-Rakic PS, Castner SA, Svensson TH, Siever LJ, Williams GV (2004) Targeting the dopamine D1 receptor in schizophrenia: insights for cognitive dysfunction. Psychopharmacology 174:3-16
19. Granon S, Passetti F, Thomas KL, Dalley JW, Everitt BJ, Robbins TW (2000) Enhanced and impaired attentional performance after infusion of D1 dopaminergic receptor agents into rat prefrontal cortex. J Neurosci 20:1208-1215
20. Grubbs RA, Lewis MM, Owens-Vance C, Gay EA, Jassen AK, Mailman RB, Nichols DE (2004) 8,9-Dihydroxy-1,2,3,11b-tetrahydrochromeno[4,3,2,-de] isoquinoline (dinoxyline), a high affinity and potent agonist at all dopamine receptor isoforms. Bioorg Med Chem 12:1403-1412
21. Gulwadi AG, Korpinen CD, Mailman RB, Nichols DE, Sit SY, Taber MT (2001) Dinapsoline: characterization of a D1 dopamine receptor agonist in a rat model of Parkinson's disease. J Pharmacol Exp Ther 296:338-344
22. Haraguchi K, Ito K, Kotaki H, Sawada Y, Iga T (1997) Prediction of drug-induced catalepsy based on dopamine D1, D2, and muscarinic acetylcholine receptor occupancies. Drug Metab Dispos 25:675-684
23. Hersi AI, Rowe W, Gaudreau P, Quirion R (1995) Dopamine D1 receptor ligands modulate cognitive performance and hippocampal acetylcholine release in memory-impaired aged rats. Neuroscience 69:1067-1074
24. Hu XT, Brooderson RJ, White FJ (1992) Repeated stimulation of D1 dopamine receptors causes time-dependent alterations in the sensitivity of both D1 and D2 dopamine receptors within the rat striatum. Neuroscience 50:137-147
25. Imperato A, Obinu MC, Gessa GL (1995) Is in vivo striatal acetylcholine output under a tonic inhibitory control by dopamine? J Neural Transm Suppl 45:91-102
26. Isacson R, Kull B, Wahlestedt C, Salmi P (2004) A 68930 and dihydrexidine inhibit locomotor activity and D-amphetamine-induced hyperactivity in rats: a role of inhibitory dopamine D (1/5) receptors in the prefrontal cortex? Neuroscience 124:33-42
27. Knoerzer TA, Watts VJ, Nichols DE, Mailman RB (1995) Synthesis and biological evaluation of a series of substituted benzo[a] phenanthridines as agonists at D1 and D2 dopamine receptors. J Med Chem 38:3062-3070
28. Laplante F, Sibley DR, Quirion R (2004) Reduction in acetylcholine release in the hippocampus of dopamine D5 receptor-deficient mice. Neuropsychopharmacology 29:1620-1627
29. Levin ED, Rose JE (1991) Interactive effects of D1 and D2 agonists with scopolamine on radial-arm maze performance. Pharmacol Biochem Behav 38:243-246
30. Lin CW, Bianchi BR, Miller TR, Stashko MA, Wang SS, Curzon P, Bednarz L, Asin KE, Britton DR (1996) Persistent activation of the dopamine D1 receptor contributes to prolonged receptor desensitization: studies with A-77636. J Pharmacol Exp Ther 276:1022-1029
31. Lovenberg TW, Brewster WK, Mottola DM, Lee RC, Riggs RM, Nichols DE, Lewis MH, Mailman RB (1989) Dihydrexidine, a novel selective high potency full dopamine D-1 receptor agonist. Eur J Pharmacol 166:111-113
32. Missale C, Nash SR, Robinson SW, Jaber M, Caron MG (1998) Dopamine receptors: from structure to function. Physiol Rev 78:189-225
33. Neisewander JL, Fuchs RA, O'Dell LE, Khroyan TV (1998) Effects of SCH-23390 on dopamine D1 receptor occupancy and locomotion produced by intraaccumbens cocaine infusion. Synapse 130:194-204
34. Paxinos G, Watson C (1986) The rat brain in stereotaxic coordinates. Academic, San Diego
35. Salmi P, Isacson R, Kull B (2004) Dihydrexidine - the first full dopamine D1 receptor agonist. CNS Drug Rev 10:230-242
36. Seamans JK, Yang CR (2004) The principal features and mechanisms of dopamine modulation in the prefrontal cortex. Prog Neurobiol 74:1-58
37. Shirazi-Southall S, Rodriguez DE, Nomikos GG (2002) Effects of typical and atypical antipsychotics and receptor selective compounds on acetylcholine efflux in the hippocampus of the rat. Neuropsychopharmacology 26:583-594
38. Sidhu A, Kimura K (1997) A novel regulation of expression of the alpha-subunit of the G stimulatory protein by dopamine via D1 dopamine receptors. J Neurochem 68:187-194
39. Silverman PB (1991) Sensitization and conditioned rotation: apomorphine, quinpirole and SKF-38393 compared. NeuroReport 2:669-672
40. Steele TD, Hodges DB Jr, Levesque TR, Locke KW (1997) D1 agonist dihydrexidine releases acetylcholine and improves cognitive performance in rats. Pharmacol Biochem Behav 58:477-483
41. Subramaniam S, Lucki I, McGonigle P (1992) Effects of chronic treatment with selective agonists on the subtypes of dopamine receptors. Brain Res 571:313-322
42. Wang HY, Zhou LW, Friedman E, Weiss B (1993) Differential regulation of release of acetylcholine in the striatum in mice following continuous exposure to selective D1 and D2 dopaminergic agonists. Neuropharmacology 32:85-91