Accuracy of MSI testing in predicting germline mutations of MSH2 and MLH1: A case study in Bayesian meta-analysis of diagnostic tests without a gold standard

Biostatistics

Volumn 6, Issue 3, 2005, Pages 450-464

  Chen, Sining ^a,d   Watson, Patrice ^b   Parmigiani, Giovanni ^a,c  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d Wilmer Clinical Trials and Biometry   (United States)

Author keywords

Diagnostic test; Hereditary nonpolyposis colorectal cancer; Microsatellite instability; Sensitivity; Specificity

Indexed keywords

CARRIER PROTEIN; MICROSATELLITE DNA; MLH1 PROTEIN, HUMAN; MSH2 PROTEIN, HUMAN; NUCLEAR PROTEIN; PROTEIN MSH2;

ARTICLE; BAYES THEOREM; BIOMETRY; CLINICAL TRIAL; COLORECTAL TUMOR; DIAGNOSTIC PROCEDURE; GENETICS; GENOMIC INSTABILITY; HUMAN; META ANALYSIS; MUTATION; SENSITIVITY AND SPECIFICITY; STANDARD; STATISTICS;

BAYES THEOREM; BIOMETRY; CARRIER PROTEINS; COLORECTAL NEOPLASMS; GENOMIC INSTABILITY; GERM-LINE MUTATION; HUMANS; MICROSATELLITE REPEATS; MOLECULAR DIAGNOSTIC TECHNIQUES; MUTS HOMOLOG 2 PROTEIN; NUCLEAR PROTEINS; SENSITIVITY AND SPECIFICITY;

EID: 26644437903     PISSN: 14654644     EISSN: 14684357     Source Type: Journal    
DOI: 10.1093/biostatistics/kxi021     Document Type: Article

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