The influence of carbohydrate nature and drying methods on the compaction properties and pore structure of new methyl methacrylate copolymers

International Journal of Pharmaceutics

Volumn 248, Issue 1-2, 2002, Pages 157-171

  Ferrero, C ^a   Jimenez Castellanos M R ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

Compression properties; Controlled release; Heckel analysis; Matrix tablets; Methyl methacrylate (MMA) copolymers; Porosity

Indexed keywords

CELLULOSE DERIVATIVE; METHACRYLIC ACID METHYL ESTER; STARCH;

ARTICLE; BINDING AFFINITY; CONTROLLED DRUG RELEASE; DRUG STRUCTURE; DRUG SYNTHESIS; FLOW RATE; FREEZING; MATRIX TABLET; PARTICLE SIZE; POLYMERIZATION; POROSITY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; SURFACE PROPERTY; TABLET COMPRESSION;

CARBOHYDRATES; CELLULOSE; COMPRESSIVE STRENGTH; METHYLMETHACRYLATES; PARTICLE SIZE; POROSITY; STARCH; TABLETS; TECHNOLOGY, PHARMACEUTICAL;

EID: 0037032459     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(02)00432-5     Document Type: Article

References (42)

1. Armstrong N.A., Haines-Nutt R.F. Elastic recovery and surface area changes in compacted powder systems. J. Pharm. Pharmacol. 24:1972;135P-136P.
2. Artalejo, B., del Pozo, A., Faulí, C., 1988. Sistemas Matriciales, Ind. Farm. Julio/Agosto (4), 103-113.
3. Bolhuis G.K., Lerk C.F. Comparative evaluation of excipients for direct compression. Pharm. Weekbl. 108:1973;469-481.
4. Buri P., Doelker E. Formulation des comprimés a libèration prolongée. II. Matrices hydrophiles. Pharm. Acta Helv. 55:1980;189-197.
5. Carli F., Capone G., Colombo L., Magarotto L., Motta A. Surface and transport properties of acrylic polymers influencing drug release from porous matrices. Int. J. Pharm. 21:1984;317-329.
6. Castellano, I., 1997. Estudio de Copolímeros de Injerto Sintetizados Para su uso Como Excipientes de Fármacos de Liberación Controlada en Formas Orales por Compresión Directa, Ph.D thesis, País Vasco University, Spain.
7. Ciftcioglu M., Smith D.M., Ross S.B. Mercury porosimetry of ordered sphere compacts: investigation of intrusion and extrusion pore size distributions. Powder Technol. 55:1988;193-205.
8. Doelker E. Physique de la compression. Intérêt et limite des machines instrumentées pour l'optimisation de la formulation. Pharm. Acta Helv. 53:1978;1-7.
9. Doelker E. Comparative compaction properties of various microcrystalline cellulose types and generic products. Drug Dev. Ind. Pharm. 19:1993;2399-2471.
10. European Pharmacopeia, Third Ed., 1997. Council of Europe, Strasbourg, France.
11. Exner H.E., Linck E. Image analysis for characterisation of size and shape distribution of lead powders. Powder Metall. Int. 9:1977;131-133.
12. Fassihi A.R., Kanfer I. The effect of compressibility and powder flow properties on tablet weight variation. Rubinstein M.H., Pharmaceutical Technology Tableting Technology. I:1987;189-202 Ellis Horwood, Chichester, UK.
13. Ferrero, M.C., Muñoz-Ruiz, A., Velasco, M.V., Monedero, M.C., Jiménez-Castellanos, M.R., 1997. Comparative study on compaction mechanism of a new family of graft copolymers of methyl methacrylate. Sixteenth Pharmaceutical Technology Conference and Exhibition, Athens, Greece, 15-17 April, pp. 585-598
14. Ferrero M.C., Velasco M.V., Ford J.L., Rajabi-Siahboomi A., Muñoz-Ruiz A., Jiménez-Castellanos M.R. Determination of the glass transition temperature of some new methyl methacrylate copolymers using Modulated Temperature Differential Scanning Calorimetry (MTDSC). Pharm. Res. 16:1999;1464-1469.
15. Fonner D.E., Banker G.S., Swarbrick J. Micromeritics of granular pharmaceutical solids. I. Physical properties of particles prepared by five different granulation methods. J. Pharm. Sci. 55:1966;181-186.
16. Garekani H.A., Ford J.L., Rubinstein M.H., Rajabi-Siahboomi A.R. Formation and compression characteristics of prismatic polyhedral and thin plate-like crystals of paracetamol. Int. J. Pharm. 187:1999;77-89.
17. Gutiérrez-Cabria, S., 1978. Medidas de tendencia de una distribución estadística. In: Bioestadística, Second Ed., Tebar Flores, Madrid, pp. 63-80.
18. Heckel R.W. Density-pressure relationships in powder compaction. Trans. Metall. Soc. AIME. 221:1961a;671-675.
19. Heckel R.W. An analysis of powder compaction phenomena. Trans. Metall. Soc. AIME. 221:1961b;1001-1008.
20. Järvinen M.J., Juslin M.J. Evaluation of force-displacement measurements during one-sided powder compaction in a die; the influence of friction with the die wall and of the diameter of punches and die on upper and lower punch pressure. Powder Technol. 28:1981;115.
21. Jetzer W., Leuenberger H., Sucker H. Compressibility and compactibility of pharmaceutical powders. Pharm. Technol. 7:1983;32-39.
22. Juppo A.M., Yliruusi J. Effect of amount of granulation liquid on total pore volume and pore size distribution of lactose, glucose and mannitol granules. Eur. J. Pharm. Biopharm. 40:1994;299-309.
23. Kleinebudde P. Shrinking and swelling properties of pellets containing microcrystalline cellulose and low substituted hydroxypropylcellulose: I. Shrinking properties. Int. J. Pharm. 109:1994;209-219.
24. Krumme M., Schwabe L., Frömming K. Development of computerised procedures for the characterisation of the tableting properties with eccentric machines: extended Heckel analysis. Eur. J. Pharm. Biopharm. 49:2000;275-286.
25. Marín, M.T., Sánchez, J., Cerezo, A., 1988. Comprimidos de liberación prolongada de teofilina. Ind. Farm. Marzo/Abril (2), 135-139.
26. Muñoz-Ruiz, A., 1992. Diseño de Sistemas de Adquisición y Tratamiento de Datos Para Velocidad de Flujo de Polvos y Estudio de Compresión en Máquina de Comprimir Excéntrica, Aplicación en Excipientes de Compresión Directa. Ph.D. thesis, Sevilla University, Spain.
27. Muñoz-Ruiz A., Jiménez-Castellanos M.R. Integrated system of data acquisition for measure of flow rate. Pharm. Technol. Int. Biopharm. 8:1993;21-29.
28. Muñoz-Ruiz A., Gallego R., del Pozo M., Jiménez-Castellanos M.R., Domínguez-Abascal J. A comparison of three methods of estimating displacement on an instrumented single punch tablet machine. Drug Dev. Ind. Pharm. 21:1995;215-227.
29. Nokhodchi A., Rubinstein M.H., Ford J.L. The effect of particle size and viscosity grade on the compaction properties of hydroxypropylmethylcellulose 2208. Int. J. Pharm. 126:1995;189-197.
30. Nyström C., Alderborn G., Duberg M., Karehill P. Bonding surface area and bonding mechanism - two important factors for the understanding of powder compactability. Drug Dev. Ind. Pharm. 19:1993;2143-2196.
31. Paronen P. Compressional characteristics of four starches. J. Pharm. Pharmacol. 35:1986;627-635.
32. Pontier C., Viana M., Champion E., Bernache-Assollant D., Chulia D. About the use of stoichiometric hydroxyapatite in compression-incidence of manufacturing process on compressibility. Eur. J. Pharm. Biopharm. 51:2001;249-257.
33. Pospěch R., Schneider P. Powder particle sizes from mercury porosimetry. Powder Technol. 59:1989;163-171.
34. Ridgway C.J., Ridgway K., Matthews G.P. Modelling of the void space of tablets compacted over a range of pressures. J. Pharm. Pharmacol. 49:1997;377-383.
35. Roberts R.J., Rowe R.C. The effect of punch velocity on the compaction of a variety of materials. J. Pharm. Pharmacol. 37:1985;377-384.
36. Rootare, H.M., Nyce, A.C., 1971. Use of porosimetry in the measurement of pore size distribution in porous materials. Int. J. Powder Metall. 7 (1) 3, 5-11.
37. Salomon J.L., Doelker E. Formulation des comprimés à liberation prolongée. I. Matrices inertes. Pharm. Acta Helv. 55:1980;174-182.
38. Sonnergaard J.M. A critical evaluation of the Heckel equation. Int. J. Pharm. 193:1999;63-71.
39. Stamm A. Choix des excipients pour formes orales solides. Labo. Pharma. Probl. Tech. 26:1978;1001-1010.
40. Velasco M.V., Muñoz-Ruiz A., Monedero M.C., Jiménez-Castellanos M.R. Study of flowability of powders. Effect of the addition of lubricants. Drug Dev. Ind. Pharm. 21:1995;2385-2391.
41. Viana M., Jouannin P., Pontier C., Chulia D. About pycnometric density measurements. Talanta. 57:2002;583-593.
42. te Wierik G.H.P., Bergsma J., Arends-Scholte A.W., Boersma T., Eissens A.C., Lerk C.F. A new generation of starch products as excipient in pharmaceutical tablets. I. Preparation and binding properties of high surface area potato starch products. Int. J. Pharm. 134:1996;27-36.