Oxalomalate, a competitive inhibitor of NADP+-dependent isocitrate dehydrogenase, regulates heat shock-induced apoptosis

Biochemical and Biophysical Research Communications

Volumn 337, Issue 2, 2005, Pages 685-691

  Hyun, Jeong Kim ^a   Park, Jeen Woo ^a  

^a Kyungpook National University   (South Korea)

Author keywords

Apoptosis; Heat shock; Isocitrate dehydrogenase; Oxalomalate; Redox status

Indexed keywords

ANTIOXIDANT; CARBOXYLIC ACID DERIVATIVE; CASPASE 3; ISOCITRATE DEHYDROGENASE (NADP); OXALOMALATE; OXIDOREDUCTASE INHIBITOR; PROTEIN BAX; PROTEIN BCL 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL FUNCTION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; ENZYME ACTIVATION; HEAT SHOCK; HUMAN; HUMAN CELL; MITOCHONDRION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; UPREGULATION;

APOPTOSIS; CASPASE 3; CASPASES; DOWN-REGULATION; ENZYME INHIBITORS; HEAT-SHOCK RESPONSE; HUMANS; ISOCITRATE DEHYDROGENASE; NADP; OXALATES; OXIDATION-REDUCTION; PROTO-ONCOGENE PROTEINS C-BCL-2; U937 CELLS; UP-REGULATION;

EID: 26444596553     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.09.104     Document Type: Article

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