Compartmentalization of hnRNP-K during cell cycle progression and its interaction with calponin in the cytoplasm

Journal of Cellular Biochemistry

Volumn 95, Issue 5, 2005, Pages 1042-1056

  Laury Kleintop, Lisa D ^a   Tresini, Maria ^a   Hammond, Olivia ^a  

^a LANKENAU INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

2D gel electrophoresis; Cycloheximide; ERK1 2; Isoforms; K protein; Protein partners; Smooth muscle

Indexed keywords

CALPONIN; CYCLOHEXIMIDE; HETEROGENOUS NUCLEAR RIBONUCLEOPROTEIN COMPLEX K PROTEIN; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RIBONUCLEOPROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER CELL; CARDIOVASCULAR DISEASE; CELL CYCLE; CELL NUCLEUS; CELL PROLIFERATION; COMPLEX FORMATION; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; CORONARY ARTERY OBSTRUCTION; CYTOPLASM; GEL ELECTROPHORESIS; HUMAN; HUMAN TISSUE; IN VITRO STUDY; NONHUMAN; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER;

ANIMALS; AORTA; BLOTTING, WESTERN; CALCIUM-BINDING PROTEINS; CELL CYCLE; CELL NUCLEUS; CELL PROLIFERATION; CHOLESTEROL, DIETARY; CYCLOHEXIMIDE; CYTOPLASM; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN K; HUMANS; IMMUNOPRECIPITATION; MICROFILAMENT PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYOCYTES, SMOOTH MUSCLE; PROTEIN TRANSPORT; RABBITS; SUBCELLULAR FRACTIONS;

ANIMALIA;

EID: 26444568259     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.20486     Document Type: Article

References (57)

1. Bomsztyk K, Van Seuningen I, Suzuki H, Denisenko O, Ostrowski J. 1997. Diverse molecular interactions of the hnRNP K protein. FEBS Lett 403:113-115.
2. Bomsztyk K, Denisenko O, Ostrowski J. 2004. hnRNP K: One protein multiple processes. Bioessays 26:629-638.
3. Chen C, Kobayashi R, Helfman D. 1999. Binding of hnRNP H to an exonic splicing silencer is involved in the regulation of alternative splicing of the rat beta-tropomyosin gene. Genes Dev 13:593-606.
4. Consigny P, Tulenko T, Nicosia R. 1986. Acute effects of angioplasty on vascular smooth muscle. Arteriosclerosis 6:265-276.
5. de Hoog CL, Foster LJ, Mann M. 2004. RNA and RNA binding proteins participate in early stages of cell spreading through spreading initiation centers. Cell 117:649-662.
6. Dejgaard K, Leffers H, Rasmussen HH, Madssen P, Kruse TA, Cesser B, Nielsen H, E CJ. 1994. Identification, molecular cloning, expression, and chromosome mapping of a family of transformation upregulated hnRNP-K proteins derived by alternative splicing. J Mol Biol 236:33-48.
7. Denisenko O, O'Neill B, Ostrowski J, Van Seuningen I, Bomsztyk K. 1996. Zik1, transcriptional represser that interacts with the heterogeneous nuclear ribonucleoprotein particle K protein. J Biol Chem 271:27701-27706.
8. Du Q, Melnikova I, Gardner P. 1998. Differential effects of heterogeneous nuclear ribonucleoprotein K on Sp1- and Sp3-mediated transcriptional activation of a neuronal nicotinic acetylcholine receptor promoter. J Biol Chem 273:19877-19883.
9. Expert-Bezancon A, Le Caer J, Marie J. 2002. Heterogeneous nuclear ribonucleoprotein (hnRNP) K is a component of an intronic splicing enhancer complex that activates the splicing of the alternative exon 6A from chicken b-tropomyosin pre-mRNA. J Biol Chem 277:16614-16623.
10. Favaloro R. 1998. Critical analysis of coronary artery bypass graft surgery: A 30 year journey. J Am Coll Cardiol 31:1B-63B.
11. Francis MK, Phinney DG, Ryder K. 1995. Analysis of the hormone-dependent regulation of a JunD-estrogen receptor chimera. J Biol Chem 270:11052-11513.
12. Geng Y, Libby P. 2002. Progression of atheroma: A struggle between death and procreation. Arterioscler Thromb Vasc Biol 22:1370-1380.
13. Goldman S, et al. 1997. Predictors of graft patency 3 years after coronary bypass graft surgery. J Am Coll Cardiol 29:1563-1568.
14. Gravel P, Golaz O. 1996. Two-dimensional PAGE using carrier ampholyte pH gradients in the first dimension. In: Walker J, editor. The Protein Protocols Handbook. Totowa, New Jersey: Humana Press, Inc. pp 127-142.
15. Habelhah H, Shah K, Huang L, Burlingame A, Shokat K, Ronai Z. 2001a. Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue. J Biol Chem 276:18090-18095.
16. Habelhah H, Shah K, Huang L, Ostareck-Lederer A, Burlingame A, Shokat K, Hentze M, Ronai Z. 2001b. ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation. Nat Cell Biol 3:325-330.
17. Hamilton B, Nichols R, Tsukamoto H, Boado R, Pardridge W, Rigby W. 1999. hnRNP A2 and hnRNP L bind the 3′UTR of glucose transporter 1 mRNA and exist as a complex in vivo. Biochem Biophys Res Comm 261:646-651.
18. Huang H, Tam M, Tam T, Chen D, Hsieh M, Li C. 2002. Proteomic analysis of stable protein methylation in lymphoblastoid cells. J Biochem 132:813-818.
19. Kim J, Paek K, Choi K, Kim T, Hahm B, Kim K, Jang S. 2003. Heterogeneous nuclear ribonucleoprotein C modulates translation of c-myc in a cell cycle phase-dependent manner. Mol Cell Biol 23:708-720.
20. Kimura E, Abe K, Suzuki K, Sorimachi H. 2003. Heterogenous nuclear ribonucleoprotein K interacts with and is proteolyzed by calpain in vivo. Biosci Biotechnol Biochem 67:1786-1796.
21. Klimek-Tomczak K, Wyrwicz LS, Jain S, Bomsztyk K, Ostrowski J. 2004. Characterization of hnRNP K protein-RNA interactions. J Mol Biol 342:1131-1141.
22. Koffa M, Kean J, Zachos G, Rice S, Clements J. 2003. CK2 protein kinase is stimulated and redistributed by functional herpes simplex virus ICP27 protein. J Virol 77:4315-4325.
23. Laury-Kleintop LD, Gleason M, Tulenko TN. 1999. Expression of the heterogeneous nuclear ribonucleoprotein complex K protein and the prolyl-4-hydroxylase a-subunit in atherosclerotic arterial smooth muscle cells. Biochem Biophys Res Comm 260:382-389.
24. Lee MH, Mori S, Raychaudhuri P. 1996. trans-Activation by the hnRNP-K protein involves and increase in RNA synthesis from the reporter genes. J Biol Chem 271:3420-3427.
25. Leinweber B, Leavis P, Grabarek Z, Wang C, Morgan K. 1999. Extracellular regulated kinase (ERK) interaction with actin and the calponin homology (CH) domain of antin-binding proteins. Biochem J 344:117-123.
26. Liu J, Beqaj S, Yang Y, Honore B, Schuger L. 2001. Heterogeneous nuclear ribonucleoprotein-H plays a suppressive role in visceral myogenesis. Mech Dev 104:79-87.
27. Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with the folin phenol reagent. J Biol Chem 193:265-275.
28. Matunis M, Michael WM, Dreyfuss G. 1992. Characterization and primary structure of the poly (C)-binding heterogeneous nuclear riboprotein complex K protein. Molec and Cell Biol 12:164-171.
29. Menice C, Hulvershorn J, Adam L, Wang C-L, Morgan K. 1997. Calponin and mitogen-activated protein kinasae signaling in differentiated vascular smooth muscle. J Biol Chem 272:25157-25161.
30. Miau L, Chang C, Shen B, Tsai W, Lee S. 1998. Identification of heterogeneous nuclear ribonucleoprotein K (hnRNP K) as a represser of C/EBPb-mediated gene activation. J Biol Chem 273:10784-10791.
31. Micheal W, Eder P, Dreyfuss G. 1997. The K nuclear shuttling domain: A novel signal for nuclear import and nuclear export in the hnRNP K protein. EMBO J 16:3587-3598.
32. Michelotti EF, Muchelotti GA, Aronsohn AI, Levens D. 1996. Heterogenous nuclear ribonucleoprotein K is a transcription factor. Mol Cell Biol 16:2350-2360.
33. Morgan K, Gangopadhyay S. 2001. Signal transduction in smooth muscle. Invited review: Cross-bridge regulation by thin filament-associated proteins. J Appl Physiol 91:953-962.
34. Mulshine J, De Luca L, Dedrick R, Tockman M, Webster R, Placke M. 2000. Considerations in developing successful, population-based molecular screening and prevention of lung cancer. Cancer 89:2465-2467.
35. Nichols R, Wang X, Tang J, Hamilton B, High F, Herschmen H, Rigby W. 2000. The RGG domain in hnRNP A2 affects subcellular localization. Exp Cell Res 256:522-532.
36. Ostareck-Lederer A, Ostareck D, Cans C, Neubauer G, Bomsztyk K, Superti-Furga G, Hentze M. 2002. c-Src-mediated phosphorylation of hnRNP-K drives translational activation of specifically silenced mRNAs. Mol Cell Biol 22:4535-4543.
37. Ostrowski J, Bomsztyk K. 2003. Nuclear shift of hnRNP K protein in neoplasms and other states of enhanced cell proliferation. Br J Cancer 89:1493-1501.
38. Ostrowski J, Schullery D, Denisenko O, Higaki Y, Watts J, Aebersold R, Stempka L, Gschwendt M, Bomsztyk K. 2000. Role of tyrosine phosphorylation in the regulation of the interaction of heterogenous nuclear riboprotein K protein with its protein and RNA partners. J Biol Chem 275:3619-3628.
39. Ostrowski J, Wyrwicz L, Rychlewski L, Bomsztyk K. 2002. Hetergenous nuclear ribonucleoprotein K protein associates with multiple mitochondrial transcripts within the organelle. J Biol Chem 277:6303-6310.
40. Persson P, Skalweit A, Mrowka R, Thiele B. 2003. Control of renin synthesis. Am J Physiol Regul Integr Comp Physiol 285:R491-R497.
41. Ross R. 1986. The pathogenesis of atherosclerosis-an update. N Engl J Med 314:488-500.
42. Ross R, Masuda J, Raines EW, et al. 1990. Localization of PDGF-B protein in macrophages in all phases of atherogenesis. Science 248:1009-1012.
43. Schreiber E, Matthias P, Muller M, Schaffner W. 1989. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucl Acid Res 17:6419.
44. Schullery D, Ostrowski J, Denisenko O, Stempa L, Shnyreva M, Suzuki H, Gschwendt M, Bomsztyk K. 1999. Regulated interaction of protein kinase Cg with the heterogeneous nuclear ribonuclear K protein. J Biol Chem 274:15101-15109.
45. Shih S, Claffey K. 1999. Regulation of human vascular endothelial growth factor mRNA stability in hypoxia by heterogeneous nuclear ribonucleoprotein L. J Biol Chem 274:1359-1365.
46. Shnyreva M, Schullery D, Suzuki H, Higaki Y, Bomsztyk K. 2000. Interaction of two multifunctional proteins: Heterogeneous nuclear ribonucleoprotein K and Y-box-binding protein. J Biol Chem 275:15498-15503.
47. Skalweit A, Doller A, Huth A, Katme T, Persson P, Thiele B. 2003. Posttranscriptional control of renin synthesis. Identification of proteins interacting with renin mRNA 3′-untranslated region. Circ Res 92:419-427.
48. Sriram V, Patterson C. 2001. Cell cycle in vasculoproliferative diseases: Potential inteventions and routes of delivery. Circulation 103:2414-2419.
49. Stone J, Collins T. 2002. Rapid phosphorylation of heterogeneous nuclear ribonucleoprotein C1/C2 in response to physiologic levels of hydrogen peroxide in human endothelial cells. J Biol Chem 277:15621-15628.
50. Stone J, Maki J, Collins T. 2003. Basal and hydrogen peroxide stimulated sites of phosphorylation in heterogeneous nuclear ribonucleoprotein C1/C2. Biochemistry 42:1301-1308.
51. Takimoto M, Tomonaga T, Matunis M, Avigan M, Krutzsch H, Dreyfuss G, Levens D. 1993. Specific binding of heterogeneous ribonucleoprotein particle protein K to the human c-myc promoter, in vitro. J Biol Chem 268:18249-18258.
52. Tolnay M, Vereshchagina L, Tsokos G. 1999. Hetergeneous nuclear ribonucleoprotein DOB is a asequence-specific DNA-binding protein. Biochem J 338:417-425.
53. Tolnay M, Juang Y, Tsokos G. 2002. Protein kinase A enhances, whereas glycogen sythase kinase-3b inhibits, the activity of the exon 2-encoded transactivator domain of heterogeneous nuclear ribonucleoprotein D in a hierarchical fashion. Biochem J 363:127-136.
54. Van Seuningen I, Ostrowski J, Bustelo X, Sleath P, Bomsztyk K. 1995. The K protein domain that recruits the Interleukin 1-responsive K protein kinase lies adjacent to a cluster of c-Src and Vav SH3-binding sites. J Biol Chem 270:26976-26985.
55. Vindelov L, Christensen I, Nissen N. 1983. A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis. Cytometry 3:323-327.
56. Wada K, Inoue K, Hagiwara M. 2002. Identification of methylated proteins by protein arginine N-methyltransferase 1, PRMT1, with a new expression cloning strategy. Biochim Biophys Acta 1591:1-10.
57. Wadd S, Bryant H, Filhol O, Scott J, Hsieh T-Y, Everett R, Clements J. 1999. The multifunctional herpes simplex virus IE63 protein interacts with heterogenous ribonucleoprotein K and with casein kinase 2. J Biol Chem 274:28991-28998.