Preparation of poly(N-isopropylacrylamide) copolymers and preliminary assessment of their acute and subacute toxicity in mice

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 61, Issue 3, 2005, Pages 188-194

  Malonne, Hugues ^a,b   Eeckman, Frédéric ^a   Fontaine, David ^a   Otto, Anne ^a   De Vos, Louis ^a   Moës, André ^a   Fontaine, Jeanine ^a   Amighi, Karim ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b Institut de Pharmacie   (Belgium)

Author keywords

Acute toxicity; N isopropylacrylamide; PNIPAAm; PNIPAAm co AAc; PNIPAAm co NVA; Subacute toxicity; Thermoresponsive polymer

Indexed keywords

ACETAMIDE DERIVATIVE; COPOLYMER; N VINYLACETAMIDE; POLY(N ISOPROPYLACRYLAMIDE); POLY(N ISOPROPYLACRYLAMIDE) CO ACRYLIC ACID; POLY(N ISOPROPYLACRYLAMIDE) CO N VINYLACETAMIDE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPSY; BODY WEIGHT; CONTROLLED STUDY; DRUG TOLERABILITY; FEMALE; FOOD INTAKE; MALE; MOUSE; NONHUMAN; ORGAN WEIGHT;

ACRYLAMIDES; ACRYLATES; ANIMALS; MICE; NO-OBSERVED-ADVERSE-EFFECT LEVEL; POLYMERS;

EID: 26444552397     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2005.05.007     Document Type: Article

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