Is an increase in CD4/CD8 T-cell ratio in lymph node fine needle aspiration helpful for diagnosing Hodgkin lymphoma? A study of 85 lymph node FNAs with increased CD4/CD8 ratio

CytoJournal

Volumn 2, Issue , 2005, Pages

  Hernandez, Osvaldo ^a   Oweity, Thaira ^a   Ibrahim, Sherif ^a  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; ASPIRATION BIOPSY; CANCER DIAGNOSIS; CELL STRUCTURE; CYTOLOGY; DIAGNOSTIC PROCEDURE; FEMALE; FLOW CYTOMETRY; FOLLOW UP; HISTOLOGY; HODGKIN DISEASE; HUMAN; LYMPH NODE BIOPSY; LYMPHADENOPATHY; LYMPHOCYTE PROLIFERATION; LYMPHOPROLIFERATIVE DISEASE; MAJOR CLINICAL STUDY; MALE; T LYMPHOCYTE; TIME SERIES ANALYSIS;

EID: 26444544999     PISSN: 17426413     EISSN: 17426413     Source Type: Journal    
DOI: 10.1186/1742-6413-2-14     Document Type: Article

References (23)

1. Habermann TM, Steensma DP: Lymphadenopathy. Mayo Clin Proc 2000, 75:723-732.
2. Buley ID: Fine needle aspiration of lymph nodes. J Clin Pathol 1998, 51:881-885.
3. Cartagena N, Katz RL, Hirsch-Ginsberg C, Childs CC, Ordonez NG, Cabanillas F: Accuracy of diagnosis of malignant lymphoma by combining fine-needle aspiration cytomorphology with immunocytometry and in selected cases, Southern blotting of aspirated cells: a tissue-controlled study of 86 patients. Diagn Cytopathol 1992, 8:456-464.
4. Steel BL, Schwartz MR, Ramzy I: Fine needle aspiration biopsy in the diagnosis of lymphadenopathy in 1,103 patients: role, limitations and analysis of diagnostic pitfalls. Acta Cytol 1995, 39:76-81.
5. Meda BA, Buss DH, Woodruff RD, et al.: Diagnosis and subclassification of primary and recurrent lymphoma: the usefulness and limitations of combined fine-needle aspiration cytomorphology and flow cytometry. Am J Clin Pathol 2000, 113:688-699.
6. Harris NL, Jaffe ES, Stein H, et al.: World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: report of the Clinical Advisory Committee meeting. J Clin Oncol 1999, 17:3835-3849.
7. Tarantino DR, McHenry CR, Strickland T, Khiyami A: The role of fine-needle aspiration biopsy and flow cytometry in the evaluation of persistent neck adenopathy. Am J Surg 1998, 176:413-417.
8. Jennings CD, Foon KA: Recent advances in flow cytometry: application to the diagnosis of hematologic malignancy. Blood 1997, 90:2863-2892.
9. Moreland WS, Geisinger KR: Utility and outcomes of fine-needle aspiration biopsy in Hodgkin's disease. Dign Cytopathol 2002, 26:278-282.
10. Vicandi B, Jimenez-Heffernan JA, Lopez-Ferrer P, et al.: Hodgkin's disease mimicking suppurative lymphadenitis: a fine-needle aspiration report of five cases. Dign Cytopathol 1999, 20:302-306.
11. Borowitz MJ, Croker BP, Metzgar RS: Immunohistochemical analysis of the distribution of lymphocyte subpopulation in Hodgkin's disease. Cancer Treat Rep 1982, 66:667-674.
12. Gupta S: Subpopulation of human T lymphocytes. Maldistribution of T cell subsets associated with abnormal locomotion of T cells in untreated adult patients with Hodgkin's disease. Clin Exp Immunol 1980, 42:186-195.
13. Gorczyca W, Weisberger J, Liu Z, et al.: An approach to diagnosis of T-cell lymphoproliferative disorders by flow cytometry. Cytometry 2002, 50:177-190.
14. Poppema S, van den Berg A: Interaction between host T cells and Reed-Sternberg cells in Hodgkin lymphomas. Sem in Cancer Biol 2000, 10:345-350.
15. Jundt F, Anagnostopoulos I, Bommert K, et al.: Hodgkin/Reed-Sternberg cells induce fibroblasts to secrete eotaxin, a potent chemoattractant for T cells and eosinophils. Blood 1999, 94:2065-2071.
16. Dong HY, Harris NL, Preffer FI, Pitman MB: Fine-needle aspiration biopsy in the diagnosis and classification of primary and recurrent lymphoma: a retrospective analysis of the utility of cytomorphology and flow cytometry. Mod Pathol 2001, 14:472-481.
17. Ravinsky E, Morales C, Kutryk E, Chrobak A, Paraskevas F: Cytodiagnosis of lymphoid proliferations by fine needle aspiration biopsy. Adjunctive value of flow cytometry. Acta Cytol 1999, 43:1070-1078.
18. Liu K, Stern RC, Rogers RT, Dodd LG, Mann KP: Diagnosis of hematopoietic processes by fine-needle aspiration in conjunction with flow cytometry: a review of 127 cases. Diagn Cytopathol 2001, 24:1-10.
19. Poppema S: Immunology of Hodgkin's disease. Baillieres Clin Haematol 1996, 9:447-457.
20. Knowles DM: Immunophenotyping and immunogenotyping approaches useful in distinguishing benign and malignant lymphoid proliferations. Semin Oncol 1993, 20:583-610.
21. Mayall F, Dray M, Stanley D, Harrison B, Allen R: Immunoflow cytometry and cell block immunohistochemistry in the FNA diagnosis of lymphoma: a review of 73 consecutive cases. J Clin Pathol 2000, 53:451-457.
22. Young NA, Al-Saleem TI, Ehya H, Smith MR: Utilization of fine-needle aspiration cytology and flow cytometry in the diagnosis and subclassification of primary and recurrent lymphoma. Cancer Cytopathol 1998, 84:252-261.
23. Beaty MW, Geisinger KR: Hodgkin lymphoma flow me? Cytojournal 2005, 2:13.