Kinetics of proton-linked flavin conformational changes in p-hydroxybenzoate hydroxylase

Biochemistry

Volumn 44, Issue 40, 2005, Pages 13304-13314

  Frederick, Kendra King ^a,b   Palfey, Bruce A ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; HYDRIDES; HYDROXYLATION; MATHEMATICAL MODELS; PH EFFECTS; PROTONS;

P-HYDROXYBENZOATE (POHB); P-HYDROXYBENZOATE HYDROXYLASE (PHBH); PROTON TRANSFER; PROTON UPTAKE;

ENZYME KINETICS;

4 HYDROXYBENZOATE 3 MONOOXYGENASE; ASPARAGINE; FLAVINE ADENINE NUCLEOTIDE; HISTIDINE; PROTOCATECHUIC ACID; PROTON; QUERCETIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SOLVENT;

ARTICLE; CHEMICAL REACTION KINETICS; CONFORMATIONAL TRANSITION; ENZYME ACTIVE SITE; ENZYME SUBSTRATE COMPLEX; HYDROXYLATION; ISOMERIZATION; PRIORITY JOURNAL; PROTON TRANSPORT; REDUCTION;

4-HYDROXYBENZOATE-3-MONOOXYGENASE; BINDING SITES; CATALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI; FLAVINS; FLUORESCENT DYES; HYDROGEN-ION CONCENTRATION; KINETICS; MIXED FUNCTION OXYGENASES; MODELS, CHEMICAL; MUTATION; NADP; PROTEIN BINDING; PROTEIN CONFORMATION; PROTONS; PSEUDOMONAS AERUGINOSA; TEMPERATURE;

EID: 26444508868     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051119t     Document Type: Article

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