Conformational changes combined with charge-transfer interactions are essential for reduction in catalysis by p-Hydroxybenzoate hydroxylase

Biochemistry

Volumn 42, Issue 38, 2003, Pages 11234-11242

  Ortiz Maldonado, Mariliz ^a   Entsch, Barrie ^a   Ballou, David P ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHARGE-TRANSFER BANDS;

CATALYSIS; CHARGE TRANSFER; CHEMICAL BONDS; COMPLEXATION; CONFORMATIONS; PH; REACTION KINETICS; REDUCTION;

ENZYME KINETICS;

4 HYDROXYBENZOATE 3 MONOOXYGENASE; 4 HYDROXYBENZOIC ACID; 5 HYDROXYPICOLINATE; FLAVINE ADENINE NUCLEOTIDE; FLAVINE MONONUCLEOTIDE; HYDRIDE; HYDROPEROXIDE; ISOALLOXAZINE; PICOLINIC ACID; PYRIDINE DERIVATIVE; QUERCETIN; SOLVENT; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; ENZYME CONFORMATION; ENZYME KINETICS; PH; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN STRUCTURE; REDUCTION;

4-HYDROXYBENZOATE-3-MONOOXYGENASE; AMINO ACID SUBSTITUTION; BINDING SITES; CATALYSIS; ESCHERICHIA COLI PROTEINS; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, MOLECULAR; NADP; OXIDATION-REDUCTION; PICOLINIC ACIDS; PROTEIN BINDING; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SPECTROPHOTOMETRY;

EID: 0141791257     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi030114y     Document Type: Article

References (35)

1. Entsch, B., and vanBerkel, W. J. H. (1995) FASEB J. 9, 476-483.
2. Palfey, B. A., and Massey, V. (1998) in Comprehensive Biological Catalysis (Sinnott, M., Ed.) Vol. III, pp 83-154, Academic Press, San Diego.
3. Palfey, B. A., Moran, G. R., Entsch, B., Ballou, D. P., and Massey, V. (1999) Biochemistry 38, 1153-1158.
4. Wang, J., Ortiz-Maldonado, M., Entsch, B., Massey, V., Ballou, D. P., and Gatti, D. L. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 608-613.
5. Massey, V., and Ghisla, S. (1974) Ann. N.Y. Acad. Sci. 227, 446-465.
6. Blankenhorn, G. (1976) in Flavins and Flavoproteins (Singer, T. P., Ed.) pp 261-267, Elsevier, Amsterdam.
7. Blankenhorn, G. (1975) Eur. J. Biochem. 50, 351-356.
8. Strickland, S., and Massey, V. (1973) J. Biol. Chem. 248, 2953-2962.
9. Schopfer, L. M., and Massey, V. (1979) J. Biol. Chem. 254, 10634-10643.
10. Mestres, J., Duran, M., and Bertrán, J. (1996) Bioorg. Chem. 24, 69-80.
11. Boon, E. M., Ceres, D. M., Drummond, T. G., Hill, M. G., and Barton, J. K. (2000) Nat. Biotechnol. 18, 1096-1100.
12. Howell, L. G., Spector, T., and Massey, V. (1972) J. Biol. Chem. 247, 4340-4350.
13. Entsch, B., Ballou, D. P., Husain, M., and Massey, V. (1976) J. Biol. Chem. 251, 7367-7379.
14. Entsch, B., Ortiz-Maldonado, M., and Ballou, D. P. (1999) in Flavins and Flavoproteins 1999 (Ghisla, S., Kroneck, P., Macheroux, P., and Sund, H., Eds.) pp 391-394, Rudolf Weber, Berlin.
15. Duesel, B., and Scudi, J. V. (1949) J. Am. Chem. Soc. 71, 1866-1867.
16. Entsch, B., Palfey, B. A., Ballou, D. P., and Massey, V. (1991) J. Biol. Chem. 266, 17341-17349.
17. Palfey, B. A., Entsch, B., Ballou, D. P., and Massey, V. (1994) Biochemistry 33, 1545-1554.
18. Moran, G. R., and Entsch, B. (1995) Protein Expression Purif. 6, 164-168.
19. Entsch, B. (1990) Methods Enzymol. 188, 138-147.
20. Moran, G. R., Entsch, B., Palfey, B. A., and Ballou, D. P. (1996) Biochemistry 35, 9278-9285.
21. Moran, G. R., Entsch, B., Palfey, B. A., and Ballou, D. P. (1997) Biochemistry 36, 7548-7556.
22. Press, W. H., Teukolsky, S. A., Vettering, W. T., and Flannery, B. P. (1992) in Numerical Recipes in C, The Art of Scientific Computing, 2nd ed., pp 683-688, Cambridge University Press, New York.
23. Metzler, D. E., and Snell, E. E. (1955) J. Am. Chem. Soc. 77, 2431-2437.
24. Chaiyen, P., Brissette, P., Ballou, D. P., and Massey, V. (1997) Biochemistry 36, 13856-13864.
25. Gatti, D. L., Palfey, B. A., Lah, M. S., Entsch, B., Massey, V., Ballou, D. P., and Ludwig, M. L. (1994) Science 266, 110-114.
26. Strickland, S., Palmer, G., and Massey, V. (1975) J. Biol. Chem. 250, 4048-4052.
27. Bevington, P. R. (1969) Data Reduction and Error Analysis for the Physical Sciences, pp 235-242, McGraw-Hill, New York.
28. Frederick, K. K., Ballou, D. P., and Palfey, B. A. (2001) Biochemistry 40, 3891-3899.
29. Husain, M., and Massey, V. (1979) J. Biol. Chem. 254, 6657-6666.
30. Gatti, D. L., Entsch, B., Ballou, D. P., and Ludwig, M. L. (1996) Biochemistry 35, 567-578.
31. Palfey, B. A., Basu, R., Frederick, K. K., Entsch, B., and Ballou, D. P. (2002) Biochemistry 41, 8438-8446.
32. Spector, T., and Massey, V. (1972) J. Biol. Chem. 247, 5632-5636.
33. Ortiz-Maldonado, M., Gatti, D. L., Ballou, D. P., and Massey, V. (1999) Biochemistry 38, 16636-16647.
34. Powlowski, J., Ballou, D., and Massey, V. (1989) J. Biol. Chem. 264, 16008-16016.
35. Palfey, B. A., and Hu, Y.-C. (2002) in Flavins and Flavoproteins 2002 (Chapman, S. K., Perham, R. N., and Scrutton, N. S., Eds.) pp 317-322, Rudolf Weber, Berlin.