Effects of R-102444 and its active metabolite R-96544, selective 5-HT 2A receptor antagonists, on experimental acute and chronic pancreatitis: Additional evidence for possible involvement of 5-HT2A receptors in the development of experimental pancreatitis

European Journal of Pharmacology

Volumn 521, Issue 1-3, 2005, Pages 156-163

  Ogawa, Taketoshi ^a   Sugidachi, Atsuhiro ^a   Tanaka, Naoki ^a   Fujimoto, Koichi ^a   Fukushige, Jun Ichiro ^a   Tani, Yoshiro ^a   Asai, Fumitoshi ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

5 HT2A receptor; Pancreatitis; R 102444; R 96544; Serotonin

Indexed keywords

2 [2[2[2(3 METHOXY)PHENYL]ETHYL]PHENOXY]ETHYL 4 HYDROXY 1 METHYLPYRROLIDINE HYDROCHLORIDE; 4 LAUROYLOXY 2 [2 [2 [2 (3 METHOXY)PHENYL]ETHYL]PHENOXY]ETHYL 1 METHYLPYRROLIDINE; AMYLASE; CERULETIDE; CHOLINE; ETHIONINE; R 102444; R 96544; SEROTONIN 2A ANTAGONIST; SEROTONIN 2A RECEPTOR; UNCLASSIFIED DRUG;

ACUTE PANCREATITIS; ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL VACUOLE; CHRONIC PANCREATITIS; CONTROLLED STUDY; CYSTIC FIBROSIS; DIET; DISEASE COURSE; DOSE RESPONSE; ENZYME ACTIVITY; HISTOLOGY; INFLAMMATION; MALE; NONHUMAN; ORGAN WEIGHT; PANCREAS; PANCREAS DUCT LIGATION; PANCREAS NECROSIS; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN FUNCTION; RAT; RAT STRAIN;

ACUTE DISEASE; AMYLASES; ANIMALS; CAERULEIN; CHOLINE; CHRONIC DISEASE; DIETARY SUPPLEMENTS; ETHIONINE; INJECTIONS, INTRAPERITONEAL; LIGATION; LIPASE; MALE; ORGAN SIZE; PANCREAS; PANCREATIC DUCTS; PANCREATITIS; PYRROLIDINES; RATS; RATS, INBRED STRAINS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT2A; SEROTONIN ANTAGONISTS; TIME FACTORS;

EID: 26444507769     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.08.033     Document Type: Article

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