Neoadjuvant chemoradiation increases the risk of pelvic sepsis after radical excision of rectal cancer

Diseases of the Colon and Rectum

Volumn 48, Issue 10, 2005, Pages 1868-1874

  Buie, W Donald ^a,b   MacLean, Anthony R ^a   Attard, Jo Anne P ^a   Brasher, Penelope M A ^a   Chan, Alexander K ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b FOOTHILLS HOSPITAL   (Canada)

Author keywords

Chemotherapy; Postoperative complications; Radiation; Rectal neoplasms

Indexed keywords

FLUOROURACIL; FOLINIC ACID; MITOMYCIN C;

ADJUVANT CHEMOTHERAPY; ADULT; AGED; CANCER RADIOTHERAPY; COMPARATIVE STUDY; CONFIDENCE INTERVAL; CONTROLLED STUDY; DEMOGRAPHY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PELVIC DISEASE; PELVIS ABSCESS; PERIOPERATIVE PERIOD; PREDICTION; PREOPERATIVE CARE; PREOPERATIVE RADIOTHERAPY; RECTUM ABDOMINOPERINEAL RESECTION; RECTUM ANASTOMOSIS; RECTUM ANTERIOR RESECTION; RECTUM CANCER; RECTUM RESECTION; RETROSPECTIVE STUDY; REVIEW; RISK ASSESSMENT; SEPSIS; STATISTICAL SIGNIFICANCE; SURGICAL TECHNIQUE;

ABSCESS; ADULT; AGED; AGED, 80 AND OVER; ANASTOMOSIS, SURGICAL; ANTINEOPLASTIC AGENTS; CHEMOTHERAPY, ADJUVANT; COLECTOMY; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOADJUVANT THERAPY; PELVIC INFECTION; RADIOTHERAPY, ADJUVANT; RECTAL NEOPLASMS; RETROSPECTIVE STUDIES; RISK FACTORS; SURGICAL WOUND DEHISCENCE;

EID: 26444478704     PISSN: 00123706     EISSN: 15300358     Source Type: Journal    
DOI: 10.1007/s10350-005-0154-1     Document Type: Review

References (35)

1. RJ Heald EM Husband RD Ryall 1982 The mesorectum in rectal cancer surgery-the clue to pelvic recurrence? Br J Surg 69 613 6
2. A Wibe B Moller J Norstein 2002 A national strategic change in treatment policy for rectal cancer-implementation of total mesorectal excision as routine treatment in Norway. A national audit Dis Colon Rectum 45 857 66
3. RB Arenas A Fichera D Mhoon F Michelassi 1998 Total mesenteric excision in the surgical treatment of rectal cancer: a prospective study Arch Surg 133 608 11
4. RJ Aitken 1996 Mesorectal excision for rectal cancer Br J Surg 83 214 6
5. M Murty WE Enker J Martz 2000 Current status of total mesorectal excision and autonomic nerve preservation in rectal cancer Semin Surg Oncol 19 321 8
6. AL Martling T Holm LE Rutqvist BJ Moran RJ Heald B Cedemark 2000 Effect of a surgical training programme on outcome of rectal cancer in the County of Stockholm. Stockholm Colorectal Cancer Study Group, Basingstoke Bowel Cancer Research Project Lancet 356 93 6
7. AF Leong 2003 Total mesorectal excision (TME)-twenty years on Ann Acad Med Singapore 32 159 62
8. A Tocchi G Mazzoni L Lepre 2001 Total mesorectal excision and low rectal anastomosis for the treatment of rectal cancer and prevention of pelvic recurrences Arch Surg 136 216 20
9. WL Law KW Chu 2001 Impact of total mesorectal excision on the results of surgery of distal rectal cancer Br J Surg 88 1607 12
10. E Kapiteijn EK Kranenbarg WH Steup 1999 Total mesorectal excision (TME) with or without preoperative radiotherapy in the treatment of primary rectal cancer. Prospective randomised trial with standard operative and histopathological techniques. Dutch ColoRectal Cancer Group Eur J Surg 165 410 20
11. JC Alberts A Parvaiz BJ Moran 2003 Predicting risk and diminishing the consequences of anastomotic dehiscence following rectal resection Colorectal Dis 5 478 82
12. E Rullier C Laurent JL Garrelon P Michel J Saric M Parneix 1998 Risk factors for anastomotic leakage after resection of rectal cancer Br J Surg 85 355 8
13. ND Karanjia AP Corder P Bearn RJ Heald 1994 Leakage from stapled low anastomosis after total mesorectal excision for carcinoma of the rectum Br J Surg 81 1224 6
14. A Vignali VW Fazio IC Lavery 1997 Factors associated with the occurrence of leaks in stapled rectal anastomoses: a review of 1,014 patients J Am Coll Surg 185 105 13
15. JR Tuson WG Everett 1990 A retrospective study of colostomies, leaks and strictures after colorectal anastomosis Int J Colorectal Dis 5 44 8
16. K Mealy P Burke J Hyland 1992 Anterior resection without a defunctioning colostomy: questions of safety Br J Surg 79 305 7
17. TE Pakkastie PE Luukkonen HJ Jarvinen 1994 Anastomotic leakage after anterior resection of the rectum Eur J Surg 160 293 7
18. A Laxamana MJ Solomon Z Cohen SM Feinberg HS Stern RS McLeod 1995 Long-term results of anterior resection using the double-stapling technique Dis Colon Rectum 38 1246 50
19. JE Krook CG Moertel LL Gunderson 1991 Effective surgical adjuvant therapy for high-risk rectal carcinoma N Engl J Med 324 709 15
20. Anonymous. Improved survival with preoperative radiotherapy in resectable rectal cancer. Swedish Rectal Cancer Trial. N Engl J Med 1997;336:980-7
21. E Kapiteijn CA Marijnen ID Nagtegaal 2001 Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer N Engl J Med 345 638 46
22. CA Marijnen E Kapiteijn CJ van de Velde 2002 Acute side effects and complications after short-term preoperative radiotherapy combined with total mesorectal excision in primary rectal cancer: report of a multicenter randomized trial J Clin Oncol 20 817 25
23. P Friedmann JL Garb DP McCabe 1987 Intestinal anastomosis after preoperative radiation therapy for carcinoma of the rectum Surg Gynecol Obstet 164 257 60
24. Anonymous. Randomised trial of surgery alone versus surgery followed by radiotherapy for mobile cancer of the rectum. Medical Research Council Rectal Cancer Working Party. Lancet 1996;348:1610-4
25. G Valero JA Lujan Q Hernandez 2003 Neoadjuvant radiation and chemotherapy in rectal cancer does not increase postoperative complications Int J Colorectal Dis 18 495 9
26. HK Antonsen O Kronborg 1987 Early complications after low anterior resection for rectal cancer using the EEA stapling device. A prospective trial Dis Colon Rectum 30 579 83
27. C Camma M Giunta F Fiorica L Pagliaro A Craxi M Cottone 2000 Preoperative radiotherapy for resectable rectal cancer: a meta-analysis JAMA 284 1008 15
28. Anonymous. Adjuvant radiotherapy for rectal cancer: a systematic overview of 8,507 patients from 22 randomised trials. Lancet 2001;358:1291-304
29. AK Chan AO Wong J Langevin 2000 Preoperative chemotherapy and pelvic radiation for tethered or fixed rectal cancer: a phase II dose escalation study Int J Radiat Oncol Biol Phys 48 843 56
30. W Graf B Glimelius R Bergstrom L Pahlman 1991 Complications after double and single stapling in rectal surgery Eur J Surg 157 543 7
31. R Sauer R Fietkau C Wittekind 2003 Adjuvant vs. neoadjuvant radiochemotherapy for locally advanced rectal cancer: the German trial CAO/ARO/AIO-94 Colorectal Dis 5 406 15
32. LP Fielding S Stewart-Brown R Hittinger L Blesovsky 1984 Covering stoma for elective anterior resection of the rectum: an outmoded operation? Am J Surg 147 524 30
33. ND Karanjia AP Corder PJ Holdsworth RJ Heald 1991 Risk of peritonitis and fatal septicaemia and the need to defunction the low anastomosis Br J Surg 78 196 8
34. R Golub RW Golub R Cantu Jr HD Stein 1997 A multivariate analysis of factors contributing to leakage of intestinal anastomoses J Am Coll Surg 184 364 72
35. A Fawcett M Shembekar JS Church R Vashisht RG Springall DM Nott 1996 Smoking, hypertension, and colonic anastomotic healing; a combined clinical and histopathological study Gut 38 714 8