Accumulated background variation among H2 mutant congenic strains: Elimination through PCR-based genotyping of F2 segregants

Journal of Immunological Methods

Volumn 257, Issue 1-2, 2001, Pages 137-143

  Carroll, Lara S ^a   Potts, Wayne K ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

H2 mutant; Heteroduplex; SSP PCR

Indexed keywords

PRIMER DNA;

ANIMAL TISSUE; ARTICLE; CONGENIC STRAIN; CONTROLLED STUDY; GENE LOCUS; GENE SEGREGATION; GENOTYPE; HAPLOTYPE; HETERODUPLEX ANALYSIS; HETEROZYGOSITY; HOMOZYGOSITY; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; MUTANT; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGENY; STRAIN DIFFERENCE;

ALLELES; ANIMALS; BASE SEQUENCE; CROSSES, GENETIC; DNA PRIMERS; FEMALE; H-2 ANTIGENS; HAPLOTYPES; HETEROZYGOTE; HOMOZYGOTE; MALE; MICE; MICE, CONGENIC; MICE, INBRED C57BL; MICE, MUTANT STRAINS; POLYMERASE CHAIN REACTION; VARIATION (GENETICS);

ANIMALIA;

EID: 0035500439     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(01)00456-2     Document Type: Article

References (24)

1. Sources of subline divergence and their relative importance for subines of six major inbred stains of mice
2. How pure are inbred strains of mice?
3. Serological analysis of H-2 mutations using monoclonal antibodies
4. Behavioural studies of MHC-congenic mice
5. Discrimination of H2 derived odors by untrained mice is consistent with divergence in antigen binding site residues
6. Polymorphisms in the dehydroepiandrosterone (DHEA) sulfotransferase (Std) gene on chromosome 7 distinguish the C57BL/6J and C57BL/6ByJ substrains
7. Behavioural and neuroanatomical divergence between two sublines of C57BL/6J inbred mice
8. Rates of spontaneous mutation
9. Substrain divergence in C3H inbred mice
10. Characterization of the spontaneous mutant H-2Kbm29 indicates that gene conversion in H-2 occurs at a higher frequency than detected by skin grafting
11. Some aspects of the H-2 system, the major histocompatibility system in the mouse
12. H-2 mutations: Their genetics and effect on immune function
13. Serological distinction of mutants B6.CH(zl) and B6.M505 from strain C57BL-6
14. Measuring spontaneous deleterious mutation process
15. A microsatellite-based MHC genotyping system for house mice (Mus musculus)
16. Histocompatibility gene mutation rates in the mouse: A 25-year review
17. bm14
18. Spontaneous H-2 mutants provide evidence that a copy mechanism analogous to gene conversion generates polymorphism in the major histocompatibility complex
19. The BALB/c mouse
20. Spontaneous mutations recovered as mosaics in the mouse specific-locus test
21. Typing of murine major histocompatibility complex with a microsatellite in the class II Eb gene
22. bm1 variant gene with the H-2Kb gene shows a cluster of seven nucleotide differences
23. Variations in LPS responsiveness among different mouse substrains of C3H lineage and their congenic derivative sublines
24. Experimental allergic orchitis in mice: III. Differential susceptibility and resistance among BALB/c sublines