Targeted treatment: Insights from studies of osteopontin and hypoxia

Lancet Oncology

Volumn 6, Issue 10, 2005, Pages 733-734

  Hill, Richard P ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOGEN; NICOTINAMIDE; NIMORAZOLE; OSTEOPONTIN; PIMONIDAZOLE;

CANCER RADIOTHERAPY; CANCER SURVIVAL; CLINICAL TRIAL; COMORBIDITY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DRUG TARGETING; HEAD AND NECK CANCER; HUMAN; HYPOXIA; IMMUNOHISTOCHEMISTRY; METASTASIS; NOTE; OXYGEN ELECTRODE; OXYGEN TENSION; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; RADIOSENSITIVITY; SOFT TISSUE SARCOMA; SURVIVAL RATE; TREATMENT OUTCOME; TUMOR BIOPSY; TUMOR CELL; UTERINE CERVIX CANCER;

EID: 26444454957     PISSN: 14702045     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1470-2045(05)70363-6     Document Type: Letter

References (10)

1. RH Thomlinson LH Gray The histological structure of some human lung cancers and the possible implications for radiotherapy Br J Cancer 9 1955 539-549
2. M Milosevic A Fyles D Hedley R Hill The human tumor microenvironment: invasive (needle) measurement of oxygen and interstitial fluid pressure (IFP) Semin Radiat Oncol 14 2004 249-258
3. J Overgaard JG Eriksen M Nordsmark et al. Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimorazole in radiotherapy of head and neck cancer: Results from the DAHANCA 5 randomised double-blind placebo-controlled trial Lancet Oncol 6 2005 757-764
4. J Overgaard MR Horsman Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers Semin Radiat Oncol 6 1996 10-21
5. J Bussink JH Kaanders AJ Van der Kogel Tumor hypoxia at the micro-regional level: Clinical relevance and predictive value of exogenous and endogenous hypoxic cell markers Radiother Oncol 67 2003 3-15
6. QT Le PD Sutphin S Raychaudhuri et al. Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas Clin Cancer Res 9 2003 59-67
7. JH Kaanders KI Wijffels HA Marres et al. Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer Cancer Res 62 2002 7066-7074
8. SR Rittling AF Chambers Role of osteopontin in tumour progression Br J Cancer 90 2004 1877-1881
9. P Subarsky RP Hill The hypoxic tumour microenvironment and metastatic progression Clin Exp Metastasis 20 2003 237-250
10. BB Ma RG Bristow J Kim Combined-modality treatment of solid tumors using radiotherapy and molecular targeted agents J Clin Oncol 21 2003 2760-2776