Changes in the specificity of antibodies against steroid antigens by introduction of mutations into complementarity-determining regions of the V(H) domain

Protein Engineering

Volumn 11, Issue 5, 1998, Pages

  Iba, Yoshitaka ^a   Hayashi, Nobuhiro ^a   Sawada, Jun Ichi ^b   Titani, Koiti ^a   Kurosawa, Yoshikazu ^a  

^a FUJITA HEALTH UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Antibodies; Complementarity determining regions; Phage display antibody; Steroid; Structural models

Indexed keywords

17 HYDROXYPREGNENOLONE; BOVINE SERUM ALBUMIN; HYDROCORTISONE; MONOCLONAL ANTIBODY; STEROID;

ANTIBODY PRODUCTION; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ARTICLE; COMPLEMENTARITY DETERMINING REGION; COMPUTER MODEL; CONTROLLED STUDY; IMMUNOGLOBULIN VARIABLE REGION; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN DOMAIN;

BOVINAE;

EID: 2642702546     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/11.5.361     Document Type: Article

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