Specific inhibition of phorbol ester-stimulated phospholipase D by Clostridium sordellii lethal toxin and Clostridium difficile toxin B-1470 in HEK-293 cells. Restoration by ral GTpases

Journal of Biological Chemistry

Volumn 273, Issue 13, 1998, Pages 7413-7422

  Schmidt, Martina ^a   Voß, Matthias ^a   Thiel, Markus ^a   Bauer, Bettina ^b   Grannaß, Andreas ^a   Tapp, Eva ^a   Cool, Robbert H ^b   De Gunzburg, Jean ^c   Von Eichel Streiber, Christoph ^d   Jakobs, Karl H ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^c INSERM   (France)

^d JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CLOSTRIDIUM TOXIN; GUANOSINE TRIPHOSPHATASE; MUSCARINIC M3 RECEPTOR; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE D;

ARTICLE; CLOSTRIDIUM DIFFICILE; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME SPECIFICITY; GLYCOSYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; STRAIN DIFFERENCE; TOXIN ANALYSIS;

3T3 CELLS; ANIMALS; BACTERIAL PROTEINS; BACTERIAL TOXINS; CELL LINE; CLOSTRIDIUM; CLOSTRIDIUM DIFFICILE; ENZYME ACTIVATION; GLUCOSYLTRANSFERASES; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEINS; HUMANS; MICE; PHOSPHOLIPASE D; PROTEIN KINASE C; RAL GTP-BINDING PROTEINS; RECEPTOR, MUSCARINIC M3; RECEPTORS, MUSCARINIC; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE;

EID: 2642685577     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.13.7413     Document Type: Article

References (65)

1. Exton, J. H. (1997) J. Biol. Chem. 272, 15579-15582
2. Singer, W. D., Brown, H. A., and Sternweis, P. C. (1997) Annu. Rev. Biochem. 66, 475-509
3. Liscovitch, M., and Cantley, L. C. (1995) Cell 81, 659-662
4. Ktistakis, N. T., Brown, H. A., Waters, M. G., Sternweis, P. C., and Roth, M. G. (1996) J. Cell Biol. 134, 295-306
5. English, D. (1996) Cell. Signalling 8, 341-347
6. Lacal, J. C. (1997) FEBS Lett. 410, 73-77
7. Hammond, S. M., Altschuller, Y. M., Sung, T.-C., Rudge, S. A., Rose, K., Engebrecht, J., Morris, A. J., and Frohman, M. A. (1995) J. Biol. Chem. 270, 29640-29643
8. Hammond, S. M., Jenco, J. M., Nakashima, S., Cadwallader, K., Gu, Q., Cook, S., Nozawa, Y., Prestwich, G. D., Frohman, M. A., and Morris, A. J. (1997) J. Biol. Chem. 272, 3860-3868
9. Sung, T.-C., Roper, R. L., Zhang, Y., Rudge, S. A., Temel, H., Hammond, S. M., Morris, A. J., Moss, B., Engebrecht, J., and Frohman, M. A. (1997) EMBO J. 16, 4519-4530
10. Colley, W. C., Sung, T.-C., Roll, R., Jenco, J., Hammond, S. M., Altschuller, Y., Bar-Sagi, D., Morris, A. J., and Frohman, M. A. (1997) Curr. Biol. 7, 191-201
11. Kodaki, T., and Yamashita, S. (1997) J. Biol. Chem. 272, 11408-11413
12. Brown, H. A., Gutowski, S., Moomaw, C. R., Slaughter, C., and Sternweis, P. C. (1993) Cell 75, 1137-1144
13. Cockcroft, S., Thomas, G. M. H., Fensome, A., Geny, B., Cunningham, E., Gout, I., Hiles, I., Totty, N. F., Truong, O., and Hsuan, J. J. (1994) Science 263, 523-526
14. Massenburg, D., Han, J.-S., Liyanage, M., Patton, W. A., Rhee, S. G., Moss, J., and Vaughan, M. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 11718-11722
15. Ktistakis, N. T., Brown, H. A., Sternweis, P. C., and Roth, M. G. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 4952-4956
16. Brown, H. A., Gutowski, S., Kahn, R. A., and Sternweis, P. C. (1995) J. Biol. Chem. 270, 14935-14943
17. Rümenapp, U., Geizt, M., Wahn, F., Schmidt, M., and Jakobs, K. H. (1995) Eur. J. Biochem. 234, 240-244
18. Houle, M. G., Kahn, R. A., Naccache, P. H., and Bourgoin, S. (1995) J. Biol. Chem. 270, 22795-22800
19. Shome, K., Vasudevan, C., and Romero, G. (1997) Curr. Biol. 7, 387-396
20. Bowman, E. P., Uhlinger, D. J., and Lambeth, J. D. (1993) J. Biol. Chem. 268, 21509-21512
21. Malcolm, K. C., Ross, A. H., Qiu, R. G., Symons, M., and Exton, J. H. (1994) J. Biol. Chem. 269, 25951-25954
22. Siddiqi, A. R., Smith, J. L., Ross, A. H., Qui, R.-G., Symons, M., and Exton, J. H. (1995) J. Biol. Chem. 270, 8466-8473
23. Singer, W. D., Brown, A.-H., Bokoch, G. M., and Sternweis, P. C. (1995) J. Biol. Chem. 270, 14944-14950
24. Kuribara, H., Tago, K., Yokozeki, T., Sasaki, T., Takai, Y., Morii, N., Narumiya, S., Katada, T., and Kanaho, Y. (1995) J. Biol. Chem. 270, 25667-25671
25. Kwak, J.-Y., Lopez, I., Uhlinger, D. J., Ryu, S. H., and Lambeth, J. D. (1995) J. Biol. Chem. 270, 27093-27098
26. Balboa, M. A., and Insel, P. A. (1995) J. Biol. Chem. 270, 29843-29847
27. Schmidt, M., Rümenapp, U., Bienek, C., Keller, J., von Eichel-Streiber, C., and Jakobs, K. H. (1996) J. Biol. Chem. 271, 2422-2426
28. Malcolm, K. C., Elliott, C. M., and Exton, J. H. (1996) J. Biol. Chem. 271, 13135-13139
29. Hess, J. A., Ross, A. H., Qiu, R.-G., Symons, M., and Exton, J. H. (1997) J. Biol. Chem. 272, 1615-1620
30. Jiang, H., Luo, J.-Q., Urano, T., Frankel, P., Zhimin, L., Foster, D. A., and Feig, L. A. (1995) Nature 378, 409-412
31. Carnero, A., Dolfi, F., and Lacal, J. C. (1994) J. Cell Biochem. 54, 478-486
32. Del Peso, L., Hernández, R., Esteve, P., and Lacal, J. C. (1996) J. Cell. Biochem. 61, 599-608
33. Del Peso, L., Lucas, L., Esteve, P., and Lacal, J. C. (1997) Biochem J. 322, 519-528
34. Chant, J., and Stowers, L. (1995) Cell 81, 1-4
35. Lopez, I., Burns, D. J., and Lambeth, J. D. (1995) J. Biol. Chem. 270, 19465-19472
36. Singer, W. D., Brown, H. A., Jiang, X., and Sternweis, P. C. (1996) J. Biol. Chem. 271, 4504-4510
37. Ojio, K., Banno, Y., Nakashima, S., Kato, N., Watanabe, K., Lyerly, D. M., Miyata, H., and Nozawa, Y. (1996) Biochem. Biophys. Res. Commun. 224, 591-596
38. Ohguchi, K., Banno, Y., Nakashima, S., Kato, N., Watanabe, K., Lyerly, D. M., and Nozawa, Y. (1996) Infect. Immun. 64, 4433-4437
39. Ohguchi, K., Banno, Y., Nakashima, S., and Nozawa, Y. (1996) J. Biol. Chem. 271, 4366-4372
40. Schmidt, M., Rümenapp, U., Nehls, C., Ott, S., Keller, J., von Eichel-Streiber, C., and Jakobs, K. H. (1996) Eur. J. Biochem. 240, 707-712
41. Schmidt, M., Bienek, C., Rümenapp, U., Zhang, C., Lümmen, G., Jakobs, K. H., Just, I., Aktories, K., Moos, M., and von Eichel-Streiber (1996) Naunyn-Schmiedeberg's Arch. Pharmacol. 354, 87-94
42. Schmidt, M., Hüwe, S. M., Fasselt, B., Homann, D., Rümenapp, U., Sandmann, J., and Jakobs, K. H. (1994) Eur. J. Biochem. 225, 667-675
43. Rümenapp, U., Schmidt, M., Wahn, F., Tapp, E., Grannass, A., and Jakobs, K. H. (1997) Eur. J. Biochem. 248, 407-414
44. von Eichel-Streiber, C., Meyer zu Heringdorf, D., Habermann, E., and Sartingen, S. (1995) Mol. Microbiol. 17, 313-321
45. von Eichel-Streiber, C., Boquet, P., Sauerborn, M., and Thelestam, M. (1996) Trends Microbiol. 4, 375-382
46. Just, I., Selzer, J., Hofmann, F., Green, G. A., and Aktories, K. (1996) J. Biol. Chem. 271, 10149-10153
47. Popoff, M. R., Chaves-Orlate, E., Lemichez, E., von Eichel-Streiber, C., Thelestam, M., Chardin, P., Cussac, D., Antonny, B., Chavrier, P., Flatau, G., Giry, M., de Gunzburg, J., and Boquet, P. (1996) J. Biol. Chem. 271, 10217-10224
48. Hofmann, F., Rex, G., Aktories, K., and Just, I. (1996) Biochem. Biophys. Res. Commun. 227, 77-81
49. von Eichel-Streiber, C., Harperath, U., Bosse, U., and Hadding, U. (1997) Microb. Pathog. 2, 307-318
50. Popoff, M. R. (1987) Infect. Immun. 55, 35-43
51. Liscoviteh, M., Chalifa, V., Pertile, P., Chen, C.-S., and Cantley, L. C. (1994) J. Biol. Chem. 269, 21403-21406
52. Lerosey, I., Chardin, P., de Gunzburg, J., and Tavitian, A. (1991) J. Biol. Chem. 266, 4315-4321
53. Nakano, H., Yamazaki, T., Ikeda, M., Masai, H., Mayatake, S.-I., and Saito, T. (1994) Nucleic Acids Res. 22, 543-544
54. Mardi, J., Harbour, D., Naccache, P. H., and Bourgoin, S. (1997) J. Biol. Chem. 272, 20660-20664
55. Cooper, J. A. (1987) J. Cell Biol. 105, 1473-1478
56. Aktories, K., Bärmann, M., Ohishi, I., Tsuyama, S., Jakobs, K. H., and Habermann, E. (1986) Nature 322, 390-392
57. Just, I., Selzer, J., Wilm, M., von Eichel-Streiber, C., Mann, M., and Aktories, K. (1995) Nature 375, 500-503
58. Urano, T., Emkey, R., and Feig, L. A. (1996) BMBO J. 15, 810-816
59. Feig, L. A., Urano, T., and Cantor, S. (1996) Trends Biochem. Sci. 21, 438-441
60. Yokozeki, T., Kuribara, H., Katada, T., Touhara, K., and Kanaho, Y. (1996) J. Neurochem. 66, 1234-1239
61. Yoshimura, S.-I., Nakashima, S., Ohguchi, K., Sakai, H., Shinoda, J., Sakai, N., and Nozawa, Y. (1996) Biochem. Biophys. Res. Commun. 225, 494-499
62. Yoshimura, S.-I., Ohguchi, K., Nakashima, S., Banno, Y., Nishimura, Y., Sakai, N., and Nozawa, Y. (1997) J. Neurochem. 69, 713-720
63. Béranger, F., Tavitian, A., and de Gunzburg, J. (1991) Oncogene 6, 1835-1842
64. Hinoi, T., Kishida, S., Koyama, S., Ikeda, M., Matsuura, Y., and Kikuchi, A. (1996) J. Biol. Chem. 271, 19710-19716
65. Luo, J.-Q., Liu, X., Hammond, S. M., Colley, W. C., Feig, L. A., Frohman, M. A., Morris, A. J., and Foster, D. A. (1997) Biochem. Biophys. Res. Commun. 235, 854-859